Designed for everyday life IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary

Biorespira is a non-invasive pulmonary ventilatord developed to provide an innovative and versatile approach to assisted lung ventilation, both in a clinical and daily context. Biorespira provides the ultimate technology: • High flow generator for non-invasive lung ventilation of adult patients with respiratory insufficiency, who breathe independently. • Isolated system that prevents the risk of infection for other people in the room due to the aerosol effect of the gas exhaled by the patient. • Easy-to-use and flexible clinical solution for a wide range of applications in sub-intensive care,...

Application Areas When there is no need for intubation In case of low oxygen in the blood • Non-invasive, portable solution • Improves patient’s oxygenation • Usable in hospitals, nursing homes and homes • Isolated system prevents virus spread To alleviate hospitals’ overload IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary • Pre-hospitalization, to prevent the need for ICU treatment • Post-ICU treatment or hospitalization, to reduce the need for new intubation • User-friendly touch screen interface • Cost-effective and in

What Compact & Portable • Handle • Weight 3 Kg (6.6 lb) • Size 291(W) x 259(H) x 203(D) mm User Friendly Interface • 10’’ Display • Touchscreen • Direct reading of the PEEP, SpO2 parameters and respiratory rate Use in hospitals, facilities and at home • 24V - switching power adapter AC/DC (100-240V 50-60Hz) • Built-in patient bed coupling • Oxygen hook-up through a cylinder or directly from the wall IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary Improvement of oxygenation and drainage of bronchial secretions Increase of CO2 clearance with reduction of functional...

Hospitals Biorespira avoids ICU congestion. Patients can recover in General Medicine Units IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary Nursing Homes Biorespira helps treat the elderly without transferring to hospitals Homes Biorespira helps fight oxygen deficiency while at home

Who Many types of lung ventilators already exist on the market, but o Patients with acute hypoxemic demand is higher than supply, with long lead times, at extremely high prices and mostly designed for intensive care and intubated patients. Doctors around the world agree that assisted lung ventilation is the most effective therapy for: IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary respiratory failure o Patients needing pre-oxygenation before intubation o Chronic obstructive pulmonary disease patients o Post intensive care patients o Post-surgery

o High flux generator with a turbine capable of generating high flows starting from the ambient air, mixed with medical oxygen that can be supplied via an oxygen tank or medical gas plant o Turbine operation optimizes oxygen consumption allowing the hospital’s oxygen system to support more patients connected at the same time (one patient per Biorespira) o Use with helmets and non-vented mask with antibacterial/antiviral filter creates an isolated system that prevents the risk of infection caused by the aerosol effect of the gas exhaled by the patient o Direct measurement of PEEP pressure and...

Accessories and Disposables supplied with Biorespira DISPOSABLE KIT to be chosen between: HELMET KIT 1x Hood for CPAP therapy* 2x Inter-Guard™ breathing filter with luer port 1x Inter-Guard™ breathing filter with luer port 1x Multi-channel Oxygen Tube, non-PVC, 2.1m 1x Multi-channel Oxygen Tube, non-PVC, 2.1m 1x 22mm Smoothbore Tube with soft end connectors, 22F-22F, length 1.8m 1x 22mm Smoothbore Tube with soft end connectors, 22F-22F, length 1.8m *Multiple versions available, to be selected when ordering IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and propri

About IBD Research and development of Medical Devices Conceived in London & founded in Italy in 2014 IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary Over 1 million € from investors & announcements Developed and certified an innovative device for hemodialysis

THANK YOU CONTACTS [email protected] IBD ITALIAN BIOMEDICAL DEVICES SRL. All rights reserved. Confidential and proprietary