ibi smartbone® THE NEXT FRONTIER OF BONE REGENERATION

TECHNOLOGY SmartBone® is a new hybrid bioactive bone substitute specifically developed for bone regeneration in reconstructive surgery. SmartBone® is produced by combining a bovine mineral bone matrix with bioactive resorbable polymers and collagen fragments. This new concept of composite biomaterial promotes a quick growth of the patient’s cells into SmartBone® while its biopolymers degrade, providing perfect integration and osteogenesis. BOVINE BONE MATRIX BIODEGRADABLE POLYMERS BIODEGRADABLE POLYMERS COLLAGEN FRAGMENTS OSTEOCONDUCTIVE ANGIOCONDUCTIVE COLLAGEN FRAGMENTS after 15 min in a liquid...

KEY FEATURES OPEN AND INTERCONNECTED POROSITY The microstructure of SmartBone®’s composite matrix strongly resembles the human bone in terms of open and mid-sized porosity. 100µm SmartBone® is completely resorbed and replaced by the patient’s own bone within 1-2 years: this excellent outcome grants a vital, functional bone-implant integration. SmartBone® is extremely biocompatible and is fully compliant with ISO 10993-1 requirements. FROM CHIPS TO CUSTOM-MADE GRAFTS 3 ADVANTAGES OF SMARTBONE® • Easy dust free shaping with any type of surgical tool (for example: bone cutter, drill) • Bigger defects...

ibi smQrtbone®on demand™ CUSTOM MADE GRAFTS FOR RECONSTRUCTIVE SURGERY ARE ONLY FOUR STEPS AWAY The doctor sends the patient's CT Scan in .dicom format with a brief clinical description IBI designs the graft in accordance with the doctor's clinical prescriptions IBI produces the custom made graft based on the .stl file 3 weeks later you will receive your graft ready for the surgical operation. No sterilization or extra shaping required The graft has been completely replaced and a mature lamellar bone has formed. • helps you to resolve complex situations • reduces surgery time • reduces patient's...

smartbone® CATALOGUE Our product is available in the following sizes: smartbone® Wedge SmartBone® is a C€ marked Class III Medical Device 2797

• Prepare the receiving site well - properly expand soft tissues - properly microdrill native bone • Ensure a tight contact to host bone - appropriate graft shaping - firmly tight screws • Smooth edges and corners • Use membrane to cover SmartBone® (suggested collagene or pericardium membrane) • Avoid the use of saline solution, mix it with patient blood • Do not overfill (avoid extra material, it does not shrink) • Do not mix it with other biomaterials • Do not reuse the product • Do not re-sterilise AVOID THE USE OF SALINE SOLUTION PREFER THE USE OF PATIENT BLOOD marked Class III Medical Device...

Which biopolymers are used? We use biodegradable polymers, the same used in resorbable sutures. What’s the biological mechanism of osteointegration of a bone graft? Bone generally has the ability to regenerate completely, but it requires a very small fracture space or some sort of scaffold to do so. Indeed, bone grafting is possible because bone tissue has the ability to regenerate completely if provided the space into which to grow. As native bone grows, it will generally replace the graft material completely, resulting in a fully integrated region of new bone. The biologic mechanisms that provide...

Industrie Biomediche Insubri SA Via Cantonale 67 Mezzovico-Vira CH-6805 Switzerland Ph. +41 91 93 06 640 www.ibi-sa.com [email protected] THE NEXT FRONTIER OF BONE REGENERATION IBI is an innovative hi-tech Swiss biomedical company focused on research, development and production of medical devices for tissue engineering and regenerative medicine: substitutes, grafts, 3D matrixes and 2D scaffolds. IBI believes that regenerative medicine and tissue engineering represent the future in healthcare. IBI has advanced competencies and core skills in processing materials for biomedical applications, which...