MonoTotal - 4 Pages

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For high sensitivity in NSCLC Accurate tumor status in moments that matter.

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For high sensitivity in NSCLC MonoTotal is a sensitive tumor activity marker for detection and identification of Non-Small Cell Lung Cancer (NSCLC). By using MonoTotal , the physician can get an early indication of the course of the disease, measured in terms of tumor cell activity instead of more conventional tumor burden measurements. MonoTotal provides the physician with a helpful aid in diagnosis, prognosis and monitoring of the disease. ® Background lung cancer Lung cancer is the most frequently diagnosed cancer and the leading cause of death by cancer worldwide. It kills more people...

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MonoTotal for efficient management in lung cancer ® MonoTotal correlates well with tumor cell activity and the extent of the disease. Studies published during the last years shows that MonoTotal has a strong association with clinical response in patients. MonoTotal demonstrates high sensitivity in patients with NSCLC, independent of histotype. The overall sensitivity is about 70-75%, at 95% specificity and correlates well with tumor cell activity and the extent of the disease. ® MonoTotal sensitivity in non-small cell lung cancer (NSCLC) patients (stages Ia-IIIb) ® ROC-analysis – AUC (Area...

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At a glance MonoTotal - For high sensitivity in NSCLC ® MonoTotal is a tumor marker measuring the cytokeratins 19, 8 and 18 in serum ® MonoTotal is an indicator of tumor cell activity which provides the clinician with early signals about disease course ® MonoTotal demonstrates high diagnostic sensitivity for non-small cell lung cancer (NSCLC) ® MonoTotal is an aid in monitoring disease progression during the course of disease and treatment outcome ® MonoTotal levels decrease in response to successful treatment Increased MonoTotal levels during follow up may indicate relapse References: 1....

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