UBC® Rapid

UBC® Rapid

UBC® Rapid

Product catalog summary
Introduction
UBC® Rapid is a diagnostic tool designed for the detection and monitoring of bladder cancer. It is particularly effective for papillary non-invasive high-grade tumors and carcinoma in situ (CIS). The test measures soluble fragments of cytokeratin 8 and 18 in urine samples, providing results quickly during patient visits.
Background
Bladder cancer is a prevalent cancer worldwide, with transitional cell carcinoma (TCC) being the most common type. Men are at a higher risk than women, and factors such as smoking and exposure to industrial chemicals increase the risk. Traditional detection methods include cystoscopy and urine cytology, but these have limitations in sensitivity and invasiveness.
Diagnostic Advantages
UBC® Rapid offers improved sensitivity over urine cytology and can detect additional tumors when used in combination with cytology. It is a point-of-care (POC) test that provides quantitative results, enhancing reproducibility and risk stratification. The test is not affected by blood contamination in urine, a common symptom of bladder cancer.
Performance and Sensitivity
Studies have shown that UBC® Rapid has a high diagnostic sensitivity for CIS (87%) and non-invasive high-grade tumors (71%). It is effective in detecting bladder cancer missed by initial cytology or cystoscopy and is suitable for use in laboratory-independent settings.
Clinical Evaluation
The UBC® Rapid test platform has been evaluated in multicenter studies, demonstrating its effectiveness in detecting bladder cancer with a sensitivity of 88% when combined with cytology. It is considered equivalent to ELISA in accuracy for bladder cancer patients.
Conclusion
UBC® Rapid is a valuable tool for early detection and monitoring of bladder cancer, offering quick results and high sensitivity. It is recommended as an adjunct to standard diagnostic methods, providing physicians with early signs of tumor recurrence during treatment monitoring.
References
The document cites several studies and evaluations supporting the effectiveness of UBC® Rapid in bladder cancer detection.
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Catalog excerpts

UBC® Rapid-1

UBC® TPS® TPAcyk™ TUBEX® IDL MonoTotal®

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UBC® Rapid-2

For Bladder Cancer detection UBC® Rapid is a powerful diagnostic parameter in primary diagnosis and follow-up of bladder cancer, especially for papillary non-invasive high-grade tumors and carcinoma in situ (CIS). UBC® Rapid performs better than urine cytology in many patients due to improved sensitivity and the combination of UBC® Rapid and cytology enables detection of additional tumors as opposed to cytology alone. One clear advantage is that UBC® Rapid can be performed immediately and the result will be available during the patient visit. Background Bladder cancer is a common cancer in men...

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UBC® Rapid-3

“UBC® Rapid provides the physician with early signs of tumor recurrence during treatment monitoring”. Marie Torstensson Product Manager, IDL Biotech AB UBC® Rapid UBC® Rapid is a point-of-care (POC) test that specifically measures soluble fragments of cytokeratin 8 and 18 in urine samples. UBC® Rapid shall be used for quantitative determination in combination with the POC-reader concile® Q100. The outcome of bladder cancer depends on how advanced it is when it is diagnosed; aggessive non-muscle invasive bladder cancer, muscle invasive or confined to the bladder. Studies have demonstrated that...

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UBC® Rapid-4

UBC® Rapid– For Bladder Cancer detection TIME COUNTS • Easy and rapid to perform • Result within 10 minutes – during the patient visit. FAST FACTS UBC® Rapid • The only quantitative POC test platform for urine based detection of bladder cancer. • Works in haematuria • UBC® also available as ELISA/IRMA References: 1. Giannopoulus A., et al. Comparative evaluation of the diagnostic performance of the BTA Stat test,NMP22 and Urinary Bladder Cancer antigen for primary and recurrent bladder tumors. J Urol 2001; 166:470-475. 2. Lüdecke G., et al. Comparative analysis of sensitivity to blood in the...

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