Focused Ultrasound Transcranial Neurosurgery MR guided Focused Ultrasound for Treatment of Essential Tremor, Tremor Dominant Parkinson’s Disease, Neuropathic Pain •• •• •• •• •• Immediate feedback of treatment Treatment through the intact skull Highly accurate thermal lesioning Single session procedure No ionizing radiation Excellence backed by Experience

ExAblate Neuro - Next Generation Neurosurgery ExAblate Neuro integrates magnetic resonance imaging (MRI) and high intensity focused ultrasound to provide a non-invasive, imageguided personalized treatment of brain disorders through an intact skull using no ionizing radiation. ExAblate Neuro uses intra-operative MRI for therapy planning, and continuous real-time MR thermal imaging feedback for monitoring safety and efficacy. The targeted tissue within the brain is ablated using high intensity ultrasound waves using a helmet-like, multi-channel high powered phased array transducer with over 1000...

Clinical Results Essential Tremor Medication-refractory patients suffering with Essential Tremor for tens of years underwent a unilateral VIM thalamotomy with ExAblate Neuro. After 3 months over 60% had an improvement in overall body score, 75% improvement in the treated side and over 92% improvement in disability. 80% reported an improvement between baseline and followup(3). Immediately post-treatment Parkinson’s Disease Patients suffering from Parkinson’s Disease underwent a thalamotomy with ExAblate Neuro. After 3 months they showed a 57.1% mean UPDRS improvement and a mean global symptom...

Excellence backed by Experience MRgFUS is a developing subspecialty of neurosurgery ExAblate Neuro patient table docked to the MR scanner 84.8% of the targeted coordinates lie within 1 mm, providing a mean targeting accuracy of the focused ultrasound treatment of 0.72 mm maximum. Such an accuracy requirement obeys clinical efficiency and safety criteria, and is globally compatible with the limitations of the target reconstruction procedure, primarily manual measurements on MR images, thickness of the MR slices (2 mm), lesion size (4x4x6 mm), and determination of the lesion center(2). “Magnetic...