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RODENT INFUSION and SAMPLING

RODENT INFUSION and SAMPLING
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RODENT INFUSION and SAMPLING

Product catalog summary
Sales Policies
Instech products are designed for laboratory research only and are not approved for human use. The company provides a limited warranty for defects, offering repair or replacement as remedies. Payment terms are net 30 days, with shipping charges added. Returns are accepted for standard items within 60 days, subject to a restocking fee, but not for custom products.
Product Overview
The catalog includes products for rodent infusion and sampling, such as infusion systems, blood sampling equipment, and microdialysis tools. Key products include infusion systems with reusable or disposable components, IV self-administration equipment, manual and automated blood sampling systems, microdialysis systems, and glucose clamp systems for hyperinsulinemic-euglycemic clamp studies.
New Products and Innovations
Recent releases include updated Vascular Access Buttons with magnetic connections and enhancements to the OrchesTA software for infusion studies, emphasizing collaboration with researchers to improve animal welfare.
Technical Specifications and Components
Specifications are detailed for each product category, including compatible components like pumps, swivels, tethers, and catheters. A tubing size reference chart and distributor information are also provided.
Conclusion
Instech Laboratories offers a comprehensive range of equipment for rodent infusion and sampling, focusing on innovation and collaboration to enhance research capabilities and animal welfare.
PinPorts™ and Vascular Access Buttons
PinPorts allow quick, aseptic access to externalized catheters in laboratory animals, available in various sizes and colors. They replace stainless steel plugs and are EtO sterilized. Vascular Access Buttons and Harnesses provide a clean way to connect implanted catheters, offering long-term patency and aseptic technique.
Specifications and Applications
PinPorts include a 3mm diameter port with a silicone septum and stainless steel connector, compatible with specific catheter sizes. They are used for direct blood sampling and infusion toxicology studies. Vascular Access Buttons are available in single and dual-channel configurations, designed for easy connection and disconnection using magnets.
Ordering Information
Part numbers and descriptions for ordering different configurations of PinPorts, injectors, buttons, and harnesses are provided, along with packaging options.
Swivels and Tubing
Swivels are available in plastic and stainless steel, designed to allow rotation of the infusion line. Tubing materials include stainless steel, Teflon, quartz, and polyimide, with specifications for compatibility and autoclavability.
Infusion Kits and Animal Enclosures
Infusion kits streamline study preparation, providing sterile equipment. Animal enclosures prevent tether tangling and meet regulatory guidelines for housing rodents.
OrchesTA™ Infusion Automation
Developed for automating preclinical infusion toxicology studies, featuring validated control and monitoring software, and clinical-grade pumps. Syringe pumps offer automated programming and error reduction features.
Syringe Pumps and Automated Blood Samplers
Pump 11 Elite and PHD Ultra series offer advanced mechanisms for smooth flow and high accuracy. The ABS2 automated blood sampler reduces stress and increases throughput, featuring precision peristaltic pumps and in-line sensors.
Fraction Collector Specifications
Includes rotary type, sample storage temperature, collection modes, and sample volume specifications. The system supports multiple samplers per computer and features electrical impedance technology for blood sensors.
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Catalog excerpts

RODENT INFUSION and SAMPLING-1

The equipment behind the science.

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RODENT INFUSION and SAMPLING-2

Sales Policies Use of Products. All Instech products are sold for laboratory research use only. Instech products have not been approved by any government agency for use on human subjects. Limited Warranty. Instech Laboratories, Inc. (“Instech”) warrants its products sold to Purchasers against defects in material or workmanship as follows: Instech will repair or replace any defective product at no charge up to 90 days (mechanical parts) or one year (electronic components) after date of purchase. Purchaser must comply with Instech’s policy regarding returns. Repair or replacement as provided under...

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RODENT INFUSION and SAMPLING-3

Infusion IV Self Administration Blood Sampling Microdialysis Glucose Clamp Whole Body Plethysmography Bile Collection Rodent Feeding Tubes Catheters PinPorts™ Buttons, Harnesses & Tethers Fluid Swivels Infusion Kits Swivel Mounts Animal Enclosures Bulk Tubing Tubing Connectors OrchesTA™ Pumps & Software Harvard Apparatus Pumps Automated Blood Sampler Tubing Size Reference Chart © Follow the links throughout this catalog for prices on specific items or download a complete price list from www.instechlabs.com/prices.

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e were there at the beginning. In the late 1960s Michael Loughnane developed a fluid swivel for a researcher at the University of Pennsylvania. He founded Instech Laboratories in 1971 and since then he and his team have designed hundreds of devices for laboratory animal research, including most of the products featured in this catalog. OrchesTA™ Software Rat Vascular Access Buttons™ The OrchesTA software and pump network can reduce infusion toxicology study labor costs by 50%. Recent enhancements cover studies with loading doses and variable flow rates. Mouse Buttons 33 Vascular Access Buttons™...

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RAT INFUSION infusion pump ontinuous intravenous infusion of rats is the most common application of Instech’s equipment. A basic system includes a catheter, exteriorization device, tether, swivel, swivel-to-cage mount and infusion pump. You have several options with a rat system: reusable or disposable components, tethers that attach to a harness worn by the rat or to a button that is surgically implanted, and a range of catheters depending on the vessel or organ you need to access. Use a Harvard Apparatus 11 Elite syringe pump for most basic experiments; for GLP studies use the advanced OrchesTA™...

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RAT INFUSION SYSTEM COMPONENTS AS SHOWN OR-100-0001 (p54) OrchesTA syringe pump HA1100 (p56) Harvard Apparatus pump CM375KRP (p45) Spring balanced mount VABR1T/22 (p28) Vascular Access Button tether VABR1B/22 Vascular Access Button, 1ch, 22ga VAH95T (p31) Vascular Access Harness tether VAH95AB Vascular Access Harness, 1ch SWIVEL MOUNT CATHETER (many other options available) US toll free 800-443-4227 • phone 610-941-0132 • www.instechlabs.com

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MOUSE INFUSION swivel swivel mount tether tubing syringe pump Vascular Access Button™ catheter infusion pump Choose your equipment carefully when setting up continuous mouse infusion studies. A typical mouse can turn a swivel with no more than 0.025oz-in of frictional torque. Instech has three models that meet this specification: a 25ga stainless steel model, a 25ga plastic model, and the 375/D/22LT dual channel model. Always use a spring counter-balanced lever arm to remove the weight of the tether from the mouse. Instech’s mouse catheters are designed for mouse anatomy on one end and, on the...

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COMPONENTS PUMP HA1100 (p56) Harvard Apparatus pump SWIVEL MOUNT SMCLA (p46) Counter-balanced lever arm Vascular Access Button tether Vascular Access Button tether Vascular Access Button, 1ch, 25ga Vascular Access Button, 1ch, 22ga CATHETER (many other options available) inSTECH US toll free 800-443-4227 • phone 610-941-0132 • www.instechlabs.com

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IV SELF ADMINISTRATION Rat infusion pump controlled by operant conditioning system jugular vein Operant chambers shown are courtesy of Med Associates, Inc. Connection Options for IV Self Administration Instech swivels, tethers and balance arms are used with operant behavior systems for IV self administration studies. A lever press or nose poke will trigger an IV dose from a syringe pump. Instech’s Vascular Access Buttons were originally developed for self-administration studies because of long-term patency and the simplicity of moving animals into and out of the operant chamber. www.instechlabs.com/Infusion/systems/selfadministration-rat.php...

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IV SELF ADMINISTRATION Mouse infusion pump controlled by operant conditioning system jugular vein I V S E L F - A D M I N I S T R AT I O N S Y S T E M S COMPATIBLE INSTECH EQUIPMENT MANUFACTURER OPERANT CHAMBER* Med Associates, Inc. St. Albans VT, USA www.med-associates.com MED-008-CT-B1 Basic rat self administration test package MED-307A-CT-B1 Basic mouse self administration test package TSE Systems GmbH Bad Homburg, Germany www.tse-systems.com PhenoMaster Behavior Operant behavior home cage monitoring system - for rats - for mice Coulbourn Instruments Whitehall PA, USA www.coulbourn.com Habitest...

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BLOOD SAMPLING Instech offers a range of equipment for laboratory animal blood sampling, from manual sampling from a catheter using the revolutionary PinPort™ to hands-free automated sampling through a tether with the ABS2™. Catheters will lose patency for blood sampling more quickly than they will for infusion. For best results use round-tip polyurethane catheters, be sure the catheter tip is in the correct location in the vessel, use a good lock solution, flush as needed but not too often (typically weekly is ideal), always use positive pressure technique, and use a closed-system such a PinPort...

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BLOOD SAMPLING Rat, Sampling + Infusion Mouse, Automated Sampling blood sample infusion pump ABS2 (p61) Automated blood sampler KVABM1T/ABS VABR2B/22 (p29) Vascular Access Button (2ch) artery carotid artery VABM1B/22 (p33) Vascular Access Button, 22ga Mouse, Manual Sampling PNP3F22 3Fr catheter VABR1B/22 (p28) Vascular Access Button, 1ch carotid artery VABM1B/22 (p33) Vascular Access Button, 22ga C15SS-RTV1438P (p22) Rat tail vein cannula, 25ga C10SS-MTV1429P (p23) Mouse tail vein cannula, 29ga US toll free 800-443-4227 • phone 610-941-0132 • www.instechlabs.com

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.