RODENT INFUSION and SAMPLING
68Pages

The equipment behind the science.

Sales Policies Use of Products. All Instech products are sold for laboratory research use only. Instech products have not been approved by any government agency for use on human subjects. Limited Warranty. Instech Laboratories, Inc. (“Instech”) warrants its products sold to Purchasers against defects in material or workmanship as follows: Instech will repair or replace any defective product at no charge up to 90 days (mechanical parts) or one year (electronic components) after date of purchase. Purchaser must comply with Instech’s policy regarding returns. Repair or replacement as provided...

Infusion IV Self Administration Blood Sampling Microdialysis Glucose Clamp Whole Body Plethysmography Bile Collection Rodent Feeding Tubes Catheters PinPorts™ Buttons, Harnesses & Tethers Fluid Swivels Infusion Kits Swivel Mounts Animal Enclosures Bulk Tubing Tubing Connectors OrchesTA™ Pumps & Software Harvard Apparatus Pumps Automated Blood Sampler Tubing Size Reference Chart © Follow the links throughout this catalog for prices on specific items or download a complete price list from www.instechlabs.com/prices.

e were there at the beginning. In the late 1960s Michael Loughnane developed a fluid swivel for a researcher at the University of Pennsylvania. He founded Instech Laboratories in 1971 and since then he and his team have designed hundreds of devices for laboratory animal research, including most of the products featured in this catalog. OrchesTA™ Software Rat Vascular Access Buttons™ The OrchesTA software and pump network can reduce infusion toxicology study labor costs by 50%. Recent enhancements cover studies with loading doses and variable flow rates. Mouse Buttons 33 Vascular Access...

RAT INFUSION infusion pump ontinuous intravenous infusion of rats is the most common application of Instech’s equipment. A basic system includes a catheter, exteriorization device, tether, swivel, swivel-to-cage mount and infusion pump. You have several options with a rat system: reusable or disposable components, tethers that attach to a harness worn by the rat or to a button that is surgically implanted, and a range of catheters depending on the vessel or organ you need to access. Use a Harvard Apparatus 11 Elite syringe pump for most basic experiments; for GLP studies use the advanced...

RAT INFUSION SYSTEM COMPONENTS AS SHOWN OR-100-0001 (p54) OrchesTA syringe pump HA1100 (p56) Harvard Apparatus pump CM375KRP (p45) Spring balanced mount VABR1T/22 (p28) Vascular Access Button tether VABR1B/22 Vascular Access Button, 1ch, 22ga VAH95T (p31) Vascular Access Harness tether VAH95AB Vascular Access Harness, 1ch SWIVEL MOUNT CATHETER (many other options available) US toll free 800-443-4227 • phone 610-941-0132 • www.instechlabs.com

MOUSE INFUSION swivel swivel mount tether tubing syringe pump Vascular Access Button™ catheter infusion pump Choose your equipment carefully when setting up continuous mouse infusion studies. A typical mouse can turn a swivel with no more than 0.025oz-in of frictional torque. Instech has three models that meet this specification: a 25ga stainless steel model, a 25ga plastic model, and the 375/D/22LT dual channel model. Always use a spring counter-balanced lever arm to remove the weight of the tether from the mouse. Instech’s mouse catheters are designed for mouse anatomy on one end and, on...

COMPONENTS PUMP HA1100 (p56) Harvard Apparatus pump SWIVEL MOUNT SMCLA (p46) Counter-balanced lever arm Vascular Access Button tether Vascular Access Button tether Vascular Access Button, 1ch, 25ga Vascular Access Button, 1ch, 22ga CATHETER (many other options available) inSTECH US toll free 800-443-4227 • phone 610-941-0132 • www.instechlabs.com

IV SELF ADMINISTRATION Rat infusion pump controlled by operant conditioning system jugular vein Operant chambers shown are courtesy of Med Associates, Inc. Connection Options for IV Self Administration Instech swivels, tethers and balance arms are used with operant behavior systems for IV self administration studies. A lever press or nose poke will trigger an IV dose from a syringe pump. Instech’s Vascular Access Buttons were originally developed for self-administration studies because of long-term patency and the simplicity of moving animals into and out of the operant chamber....

IV SELF ADMINISTRATION Mouse infusion pump controlled by operant conditioning system jugular vein I V S E L F - A D M I N I S T R AT I O N S Y S T E M S COMPATIBLE INSTECH EQUIPMENT MANUFACTURER OPERANT CHAMBER* Med Associates, Inc. St. Albans VT, USA www.med-associates.com MED-008-CT-B1 Basic rat self administration test package MED-307A-CT-B1 Basic mouse self administration test package TSE Systems GmbH Bad Homburg, Germany www.tse-systems.com PhenoMaster Behavior Operant behavior home cage monitoring system - for rats - for mice Coulbourn Instruments Whitehall PA, USA www.coulbourn.com...

BLOOD SAMPLING Instech offers a range of equipment for laboratory animal blood sampling, from manual sampling from a catheter using the revolutionary PinPort™ to hands-free automated sampling through a tether with the ABS2™. Catheters will lose patency for blood sampling more quickly than they will for infusion. For best results use round-tip polyurethane catheters, be sure the catheter tip is in the correct location in the vessel, use a good lock solution, flush as needed but not too often (typically weekly is ideal), always use positive pressure technique, and use a closed-system such a...

BLOOD SAMPLING Rat, Sampling + Infusion Mouse, Automated Sampling blood sample infusion pump ABS2 (p61) Automated blood sampler KVABM1T/ABS VABR2B/22 (p29) Vascular Access Button (2ch) artery carotid artery VABM1B/22 (p33) Vascular Access Button, 22ga Mouse, Manual Sampling PNP3F22 3Fr catheter VABR1B/22 (p28) Vascular Access Button, 1ch carotid artery VABM1B/22 (p33) Vascular Access Button, 22ga C15SS-RTV1438P (p22) Rat tail vein cannula, 25ga C10SS-MTV1429P (p23) Mouse tail vein cannula, 29ga US toll free 800-443-4227 • phone 610-941-0132 • www.instechlabs.com