Spine solutions from the leader in regenerative technology Dura protection for spine surgery

DuraGen Plus Dural Regeneration Matrix, the most advanced Dural Regeneration Matrix for spine THE DURAL REGENERATION MATRIX RESORPTION RATE MATCHES THE GROWTH RATE OF NEW TISSUE DuraGen Plus' porous architecture is specifically tailored for application in spinal duraplasty. DuraGen Plus meets the requirements of an onlay, delivers superior results Requirements Ultra Pure Collagen™ No reported foreign body reaction, fibrin clot formation for biological seal Excellent Conformability Ensures graft approximation at the dural margin Optimized Resorption Matrix resorbs at the same rate as new tissue...

Superior safety profile* • Over 300,000 implants for dural repair.1 • Minimal adhesion formation only following significant disruption of pia-arachnoid.1,2 • Effective protection against cerebrospinal fluid (CSF) leakage with sutureless closure.1,2 • Immunologically well tolerated—no foreign body reactions reported in all clinical trials.1,2 DuraGen Plus, the onlay graft of choice for spinal dural repair • Provides a simple technique for precise placement of the matrix between the dura and overlying tissues in spinal procedures3,4,5 • Handles like normal soft tissue, easily conforming to the...

DuraGen Plus™ Ordering Information Catalog Number Spine solutions from the leader in regenerative technology Integra LifeSciences Corporation 311 Enterprise Drive Plainsboro, NJ 08536 www.Integra-LS.com Customer Service: 800-997-4868 (USA and Canada) 800-654-2873 (USA and Canada) 609-275-0500 (Outside USA) 609-275-5363 (Fax) Sizes shown in inches at actual size. Adverse Events Possible complications can occur with any neurosurgical procedure and include cerebrospinal fluid leaks, infection, delayed hemorrhage and adhesion formation. In clinical evaluations involving 1,096 patients, postoperative...