DuraGen® is the simple choice. DuraGen® Secure Dural Regeneration Matrix Keep Closure Simple.

DuraGen® Secure Dural Regeneration Matrix Limit the uncertainties of dural repair with secure contact for patients with compromised margins

Enhanced Contact Assurance with DuraGen Secure Dural Regeneration Matrix In these challenging cases, keeping the graft in place and ensuring secure contact are critical steps to achieving CSF leak prevention. DuraGen® Secure helps alleviate concerns about closure by ensuring enhanced contact between the matrix and compromised dural margins. Preventing CSF Leaks with DuraGen® Secure Dural Regeneration Matrix In Patients with Compromised Dural Margins ENHANCED CONTACT ASSURANCE Compared to traditional collagen matrices, DuraGen Secure has six times more slip resistance1, maintaining contact even...

DuraGen® Secure Dural Regeneration Matrix CSF Leak Prevention in Challenging Patients For the Neurosurgeon, patients with compromised dural margins present a unique challenge. Less than ideal margins create uncertainty about achieving a watertight seal, since good graft-to-margin contact is essential to the fibrin clot formation that closes off pathways where CSF leaks might occur. Lacerated Dura Dehydrated Dura Friable Dura Dura mater may become “compromised” for a variety of reasons, including age, trauma, or intra-operative circumstance. In these patient types, it may be difficult for the...

The Science of Secure The unique, fluid activated cellulose microlayer of DuraGen Secure helps to alleviate the concern about insecure contact. Secure’s hydrostatic attraction enables the graft to stay put at the dural margins even under repeated irrigation or prolonged immersion1, offering six times more slip resistance than traditional collagen onlays2. How it Works Traditional Onlay - Contact with Surface Tension Alone • Due to its porous nature, a traditional collagen onlay matrix has a structure and volume that is mostly air. When applied, only relatively weak surface tension is available...

DuraGen® Secure Dural Regeneration Matrix All the Benefits of DuraGen® ... As with all products in the DuraGen family, the DuraGen Secure was engineered with the ideal balance of strength and flexibility to ensure optimal handling, sealing, and resorption — leaving the patient with a natural dural repair. It Starts with Ultra Pure Collagen™ Precisely Engineered Porosity Excellent Conformability and Handling ... with Enhanced Contact Assurance for Compromised Dural Margins Six Times the Slip Resistance of a Traditional Collagen Onlay Matrix Erythrocytes “Red Blood Cells” Erythrocytes “Red Blood...

Integra® DuraGen® Secure Matrix DuraGen® Secure Dural Regeneration Matrix Dural Regeneration Matrix Two Million Implants and Counting Only Integra DuraGen grafts provide the confidence of utilizing a dural matrix which has been implanted over two million times. Over 1,400 patients in 10 published clinical studies • 0% Foreign body response • 1.9% Infection rate • 2.1% Leakage rate Integra’s DuraGen products have more published human clinical data than any other collagen-based dural graft. Clinical studies have shown effective protection against CSF leakage with sutureless closure and no reports...