Integra* DuraGen* Dural Regeneration Matrix Limit uncertainty with the most studied and proven collagen-based dural grafts LIMIT UNCERTAINTY

Unsurpassed Clinical Data What is DuraGen® Matrix DuraGen matrix is one of the safest and most effective onlay grafts for the restoration and repair of dura mater. It is conformable and contours instantly and effectively to the complex, moist surfaces of the brain and spinal cord, rapidly supporting the formation of a biological seal to protect against CSF leakage. The DuraGen Matrix Difference "The Fibroblasts Use the Pores on the Matrix to Lay Down Endogenous Collagen. By 6-8 Weeks, the Collagen Matrix (DuraGen Matrix) is Resorbed and is Integrated to the Endogenous Dura Mater. The Compact...

Over 1,400 Patients • 0% Foreign body response in 10 Published • 1.9% Infection rate Clinical Studies • 2.1% Leakage rate These studies represent the use of DuraGen matrix without the use of dural sealants.

Integra® DuraGen® Matrix Unsurpassed Clinical Data 1 Million Dural Grafts and Counting Only Integra DuraGen graft provides the confidence of utilizing a dural matrix which has been implanted over one million times. 10 Million Collagen Implants and Counting Our leading technology collagen products have been implanted over 10 million times in a variety of procedures throughout the world. DuraGen Dural Regenerative Matrix • Made from Ultra Pure Collagen™ • Precisely engineered porosity for complete and natural repair • Superior conformability Summary outcome statistics derived from the following...