Integra® Tissue Technologies Limit uncertainty with a leader in collagen technology

Integra® Tissue Technologies Integra® Dermal Regeneration Template PriMatrix® Dermal Repair Scaffold A Pioneer in Regenerative Medicine Integra LifeSciences, a wordwide leader in medical technology, has offered innovative solutions to clinicians and patients for over 25 years. In 1996, the FDA approved the Company's first product, Integra® Dermal Regeneration Template, a collagen matrix designed as a skin replacement system for the treatment of third-degree burns. Integra® Dermal Regeneration Template was the first product approved with a claim of regeneration of dermal tissue. Advances in material...

What is Integra template? Integra template is an advanced bilayer matrix for dermal regeneration. The dermal replacement layer consists of a porous, three-dimensional matrix, comprised of collagen and chondroitin-6-sulfate. The temporary epidermal layer is made of a thin silicone layer to provide immediate wound coverage. Step 1 Integra template is applied to a debrided wound bed. Step 2 Cells migrate from the adjacent dermis into the collagen matrix where they synthesize and deposit collagen to Step 3 Simultaneously, endothelial cells from nearby vascular supply migrate into the matrix to support...

Integra® Tissue Technologies What is PriMatrix? PriMatrix is a unique dermal repair scaffold for the management of a broad range of wound types, including diabetic and venous ulcers. Made of pure, all-natural collagen, this novel dermal matrix provides an ideal environment to support the cellular repopulation and revascularization processes critical in wound healing. How PriMatrix Works PriMatrix is cell-friendly dermal collagen and acts as a scaffold for cells and bloods vessels as the body repairs the wound. PriMatrix Collagen Scaffold PriMatrix is a dermal repair scaffold that is consistent...

Integra® Product Portfolio Integra® Dermal Regeneration Template The first FDA approved bilayer matrix for dermal regeneration in 3rd degree burns and scar contractures Integra® Meshed Dermal Regeneration Template The only FDA approved pre-meshed bilayer matrix for dermal regeneration in 3rd degree burn and scar contractures Integra® Bilayer Wound Matrix A bilayer matrix for a variety of wounds that provides a scaffold for cellular invasion and capillary growth Integra® Meshed Bilayer Wound Matrix A pre-meshed bilayer matrix for wound management that can be used in conjunction with negative pressure...

Integra® Tissue Technologies Brief Summary Consult Package Insert for Full Prescribing Information Integra® Dermal Regeneration Template Integra® Meshed Dermal Regeneration Template Description Integra Dermal Regeneration Template, available in Meshed and Non-Meshed configurations (Integra template) is a bilayer membrane system for skin replacement. The dermal replacement layer is made of a porous matrix of fibers of cross-linked bovine tendon collagen and glycosaminoglycan (chondroitin-6-sulfate) that is manufactured with a controlled porosity and defined degradation rate. The epidermal substitute...

Brief Summary Consult Package Insert for Full Prescribing Information Integra® Wound Matrix Indications Integra® Matrix Wound Dressing is indicated for the management of wounds including: partial and full-thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites/grafts, post-Moh's surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, second-degree burns, skin tears) and draining wounds. The device is intended for one-time use. Contraindicatons • This device should...

Ordering Information Integra Dermal Regeneration Template For more information or to place an order, please contact: United States, Canada, Asia, Pacific, Latin America USA 800-654-2873 ■ 888-980-7742 fax International +1 609-936-5400 ■ +1 609-750-4259 fax integralife.com/contact Integra LifeSciences Corporation 109 Morgan Lane Plainsboro, NJ 08536 ■ USA TEI Biosciences, a subsidiary of Integra LifeSciences Corporation 7 Elkins Street Boston, MA 02127 ■ USA PriMatrix, Integra and the Integra logo are registered trademarks of Integra LifeSciences Corporation or its subsidiaries in the United States...