Introduction
DuraGen® is a dural graft matrix designed to simplify the process of dural closure in neurosurgery. It is manufactured by Integra LifeSciences Corporation and is known for its simplicity and effectiveness in dural repair.

Specifications
The DuraGen® Dural Graft Matrix is engineered with Ultra Pure Collagen™, which provides natural dural repair through its conformability and optimized porosity. It is clinically proven and supported by extensive published clinical evidence.

Clinical Evidence
DuraGen® has been demonstrated in over one million patients, with more clinical evidence supporting its use than any other dural grafts. Key studies and references include works by Narotam PK, Danish SF, and others, highlighting its efficacy in various neurosurgical procedures.

Indications and Usage
DuraGen® is indicated as a dura substitute for the repair of dura mater. It is used in cranial and spinal surgeries to aid in dural reconstruction.

Adverse Events
Potential complications associated with its use include cerebrospinal fluid (CSF) leaks, infection, delayed hemorrhage, and adhesion barrier formation. Users are advised to read the package insert for complete instructions, contraindications, and precautions.

Contact Information
For more information or to place an order, contact Integra LifeSciences Corporation at 1-800-654-2873 or visit their website at www.integralife.com.

Trademark Information
DuraGen, Integra, and the Integra logo are registered trademarks of Integra LifeSciences Corporation. Ultra Pure Collagen is a trademark of the same corporation.