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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction

SurgiMend® Collagen Matrix for Soft Tissue Reconstruction
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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction - 1

Product Summary SurgiMend® Collagen Matrix for Soft Tissue Reconstruction Because we are committed to limiting uncertainty, Integra offers SurgiMend in 1, 2, 3 or 4 mm thicknesses and in over sixty configurations, providing the most appropriate device thickness, strength, and size for each procedure, technique, and patient. LIMIT UNCERTAINTY

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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction - 2

Collagen Matrix for Soft Tissue Reconstruction Product Overview SurgiMend® is a unique acellular collagen matrix derived from fetal and neonatal bovine dermis. SurgiMend offers clear advantages over synthetic and other biologic products for soft tissue repair and reconstruction. SurgiMend is the Strongest, Thickest Biologic Matrix 9 • The biological make-up of bovine dermis, including its inherent collagen fiber architecture, leaves SurgiMend unmatched in available thicknesses and mechanical strength • 1.0, 2.0, 3.0 and 4.0 mm thicknesses and sizes up to 25 cm x 40 cm SurgiMend Offers an...

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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction - 3

SurgiMend® I00000000-Collagen Matrix for Soft Tissue Reconstruction Indications SurgiMend is intended for implantation to reinforce soft tissue where weakness exists and for surgical repair of damaged or ruptured soft tissue membranes. SurgiMend is specifically indicated for: • Plastic and reconstructive surgery. • Muscle flap reinforcement. • Hernia repair including abdominal, inguinal, femoral, diaphragmatic, scrotal, umbilical, and incisional hernias. Contraindications • SurgiMend is not designed, sold, or intended for use except as indicated. • SurgiMend should not be used for patients...

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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction - 4

Strongest, Thickest Biologic Matrices 9 SurgiMend is offered in 1.0 mm, 2.0 mm, 3.0 mm, and 4.0 mm thicknesses, providing surgeons with the widest flexibility to choose the most appropriate device thickness, strength, and size for each procedure, technique, and patient. The biological make-up of bovine dermis, including its inherent collagen fiber architecture, leaves SurgiMend unmatched in available thicknesses and mechanical strength, making it the best choice to strengthen and reinforce the repairs required in the most challenging cases. High Levels of Type III Healing Collagen During...

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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction - 5

Non-Inflammatory for Better Reinforcement Not all “biologics” are the same. Other acellular matrix products are known to elicit an acute or chronic foreign body inflammatory response that leads to the implant’s degeneration. The inflammatory response to a biologic matrix varies widely depending on source tissue composition, structure, method of processing, and the resulting uniformity and purity of the matrix to be implanted.5,6,7 Acellular Human Cadaveric Dermis Inflammatory Cells Integra’s proprietary manufacturing process preserves the beneficial properties of the natural collagen matrix...

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SurgiMend® Collagen Matrix for Soft Tissue Reconstruction - 6

SurgiMend® I00000000-Collagen Matrix for Soft Tissue Reconstruction 1 Larson et al. Scarless fetal wound healing: a basic science review” Plastic and Reconstructive Surgery 2010; 126:1172-1180. 2 Volk et al. Dimished Type III collagen promotes myofibroblast differentiation and increases scar deposition in cutaneous wound healing. Cells Tissues Organs. 2011; 194:25-37. 3 Smith LT, Holbrook KA, Madri J. Collagen types I, III and V in human embryonic and fetal skin. The American Journal of Anatomy 1986; 175:507-521. 4 Ramshaw J. Distribution of type III collagen in bovine skin of various ages....

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