angiolite Sirolimus eluting coronary stent sytem Coating durability & optimal kinetics CA

mechanical integrity Fast deflation Trilayer balloon Advanced crimping technology 1 Proprietary hydrophilic coating with long lasting durability PEBAX: anti-dislodgement Soft layer for cushion effect NYLON: anti-puncture Reinforced inner layers Open cell design Outstanding radial force Alternate spiral links * Statistically significant difference 28-day histological analysis restenosis is equivalent to Xience Assess safety & efficacy of new generation DES (angiolite) vs 2nd gen DES (Xience) and BMS Over-expansion swine model 33 stents randomized over the 3 major coronary arteries 28-day angiographic...

homogeneous drug delivery BMS - CoCr Acrylate Proprietary nanodrop coating technology Artery Coating integrity clinical trial The ANCHOR study results confirm the safety and efficacy of the Angiolite for the treatment of patients with de novo lesions. OCT 3-month follow-up Covered struts rate 86,3% High Efficacy High Safety At 6-month proven and mainly supported by binary restenosis 0% in-stent LLL 0,07mm. Supported by a very low target lesion failure rate 1%, caused by 1% of target lesion revascularization at 6-month. ANCHOR Study angiolite - Sirolimus eluting coronary stent sytem

> Rapid Exchange catheter (RX) > Compatible with 0.014” guidewire > Compatible with 5F guiding catheter > Tip profile: 0.016” > Crossing profile from 0.043” to 0.051” > 2 radiopaque markers (Pt-Ir) > Balloon material: Nylon and Pebax > Semi-compliant balloon > Mean deflation time: 3s > NP: 9-12 atm | RBP = 16 atm | ABP = 22 atm > Stent material: CoCr L605 > Strut thickness 75 pm - 85 pm > Recoil < 5% > Shortening at expansion < 3% > Drug: 1.4 pg/mm2 Sirolimus > Polymer: Fluorinated acrylate Product with CE mark, certified by Notified Body 0318 MVManufactured by:LVD Biotech, S.L. www.ivascular.global [email protected]...