M011T024A0C2

M011T024A0C2

M011T024A0C2

Product catalog summary
Overview: The document discusses the HLA-B27 PCR Test Kit, a diagnostic tool used to detect the presence of the HLA-B27 antigen, which is strongly associated with ankylosing spondylitis (AS) and other inflammatory diseases. The test kit is designed for use with EDTA anticoagulated whole blood and employs a fluorescent probe-based real-time assay.
Product Specifications:
  • Package: 24 tests per kit
  • Specimen: EDTA anticoagulated whole blood
  • Detection Time: Nucleic acid extraction takes 20 minutes, and amplification takes 60 minutes
  • Contamination Control: Utilizes dUTP/UNG systems to prevent carry-over contamination
  • Specificity: Non cross-reactivity with other HLA gene subtypes
  • Sensitivity: High sensitivity with 1ng/μL genomic DNA
Advantages:
  • Rapid Detection: Faster than flow cytometry as it does not require viable lymphoid cells
  • Easy Operation: Simplified testing process
  • High Specificity and Sensitivity: Ensures accurate results
  • Internal Control System: Prevents false negative results
Recommended PCR Instruments: The test is compatible with several PCR instruments, including ABI 7500, Stratagene MX3005P, Bio Rad CFX96, Bioer LineGene9600Plus/9660/9680, and HongShi SLAN-96P.
Clinical Significance: Testing for HLA-B27 can aid in the early diagnosis and treatment of AS, helping to prevent disease progression and reduce disability rates. It is particularly useful for screening high-risk populations with a family history of genetic markers.
Contact Information: Jiangsu Mole BioScience Co., Ltd. provides contact details for their offices in Taizhou and Hangzhou, China, for further inquiries.
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Catalog excerpts

M011T024A0C2-1

Human Leukocyte An�gen B27 PCR Test Kit (Fluorescent Probe Based Real-Time Assay) ——Indicator of ankylosing spondyli�s preven�ve (DNA) HLA-B27 is strongly associated with ankylosing spondyli�s (AS) and other related inflammatory diseases, such as psoriasis, inflammatory bowel disease and reac�ve arthri�s. HLA-B27 is present in about 90% of people with AS, but the gene can also be seen in people w

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M011T024A0C2-2

Products Advantages High Specificity Rapid Detec�on Easy Opera�on Compared to flow cytometry, PCR test not required viable lymphoid. non cross-reac�vity with other subtypes of HLA gene Nucleic Acid extrac�on 20 min + amplifica�on 60 min. Contamina�on Control High Sensi�vity dUTP/UNG systems to avoid carryover contamina�on of PCR products in subsequent amplifica�on reac�ons. Control System Prevent false nega�ve results. Through HLA-B27 tes�ng, back pain, arthralgia and other diseases similar like AS can be excluded clinically. HLA-B27 is a gene�c marker, the prompt high-risk popula�ons with family...

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Archived catalogs

  1. B052T050B0C2

    2  Pages

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