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KNIK CO.,LTD.
KNIK BIO 35L cell bioreactor for recommendation 210517

KNIK BIO 35L cell bioreactor for recommendation 210517

Product catalog summary

Overview: This document outlines the specifications and operational guidelines for KNIK Co., Ltd.'s bioreactor systems, including the KNIKBIO-100SCUC, KNIK-50-500SCUC, and KNIKBIO-35L Stainless Steel Bioreactor System. It covers equipment design, application, installation, control systems, and key components.

Equipment Design: The KNIKBIO-35L bioreactor features a 35L total volume with a 40-70% working volume. It includes heat-resistant silica glass bottles and enclosed process piping, eliminating the need for air or vapor pretreatment devices.

Application and Installation: Suitable for cultivating bacteria, plant, and mammalian cells using various methods. Delivery is within 90-120 working days, with installation by the customer.

Reactor Specifications: Constructed from 316L and 304 stainless steel, the reactor has a 70% working volume and includes sterilization and sampling options, conforming to GMP standards.

Mixing System: Features a mechanical seal with a bottom double mechanical seal and top magnetic drive, operating at 20-200 rpm.

Ventilation System: Offers bottom and top ventilation modes with automatic or manual sterilization, supporting air, oxygen, nitrogen, and carbon dioxide.

Feeding System: Utilizes peristaltic pumps for acid, base, antifoam, and nutrient solutions, allowing intermittent or continuous feeding.

Control Functions: Includes PID automatic control for sterilization, temperature, pH, DO, mixing speed, and pressure, with real-time and historical data tracking.

Key Components: Uses Siemens PLC and touch screen, with components from Hamilton, METTLER, and Bürkert.

Documentation and Client Site Conditions: Provides layout designs, piping diagrams, and control system schematics, specifying power supply and steam pressure requirements.

KNIKBIO-b Control System: Based on Siemens S7-1200 PLC, it offers a user-friendly interface and advanced PID control for precise fermentation management.

Specifications and Control Functions:

Cascade Control: Integrates control of dissolved oxygen and speed to enhance oxygen concentration, with feed control linked to pH and dissolved oxygen.
Sterilization: Automatically controls sterilization parameters and transitions to fermentation preparation post-sterilization.
Pressure Protection Test: Includes automatic detection for tank air tightness.
Setting and Calibration: Allows calibration of sensors and manual pump flow calibration.
Data Display, Record, and Storage: Offers real-time data display, recording, analysis, and storage, requiring an upper computer for full functionality.
PID Control: Provides PID control for each parameter with real-time monitoring.
Over Limit Alarm Function: Sets upper and lower limits with alarm functions for breaches.
Control Switch: Allows automatic, manual, or shutdown modes for various parameters.
Diagnosis and Protection: Features self-diagnostic capabilities with automatic alarms and protection operations.
Password Protection Function: Secures operations with password protection across different user levels.

Catalog excerpts

KNIK BIO 35L cell bioreactor for recommendation 210517-1

KNIK CO.,LTD. No. 48, Liuxiang Rd.Huating Town, JiadingDistrict,Shanghai City 1 Attn：Grace Email: [email protected]

Open the catalog to page 1

KNIK BIO 35L cell bioreactor for recommendation 210517-2

KNIK CO.,LTD. No. 48, Liuxiang Rd.Huating Town, JiadingDistrict,Shanghai City 2 50L500L Animal cell bioreactor KNIK-50-500SCUC 500L Animal cell bioreactor KNIK-500SCUC Attn：Grace Email: [email protected]

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KNIK BIO 35L cell bioreactor for recommendation 210517-3

KNIK CO.,LTD. No. 48, Liuxianq Rd.Huatinq Town, JiadinqDistrict,Shanghai City I .Confirmation of Equipment Design : Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

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KNIK BIO 35L cell bioreactor for recommendation 210517-4

Reactor/fermentation tank Attn: Grace Email: [email protected]

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KNIK BIO 35L cell bioreactor for recommendation 210517-5

KNIK CO.,LTD. No. 48, Liuxiang Rd.Huating Town, JiadingDistrict,Shanghai City 4.1 Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

Open the catalog to page 5

KNIK BIO 35L cell bioreactor for recommendation 210517-6

Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

Open the catalog to page 6

KNIK BIO 35L cell bioreactor for recommendation 210517-7

Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

Open the catalog to page 7

KNIK BIO 35L cell bioreactor for recommendation 210517-8

KNIK CO.,LTD. No. 48, Liuxian Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

Open the catalog to page 8

KNIK BIO 35L cell bioreactor for recommendation 210517-9

KNIK bio C€ ASME KNIK co.,ltd.No. 48, Liuxiang Rd.Huating Town, JiadingDistrict,Shanghai City 11.5 Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

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KNIK BIO 35L cell bioreactor for recommendation 210517-10

KNIK CO.,LTD. KNIK bio C€ ASME No. 48, Liuxian Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

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KNIK BIO 35L cell bioreactor for recommendation 210517-11

No. 48, Liuxiang Rd.Huating Town, JiadingDistrict,Shanghai City 14.1 Attn: Grace Email: [email protected] www.knikbio.com Cell/whatsapp: 0086-13968006641

Open the catalog to page 11

KNIK BIO 35L cell bioreactor for recommendation 210517-12

KNIK bio C€ ASME KNIK co.,ltd.No. 48, Liuxiang Rd.Huating Town, JiadingDistrict,Shanghai City 14.9 Attn: Grace Email: [email protected]

Open the catalog to page 12

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