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STYL‘One Nano The Benchtop Compaction Simulator

Research and Development in Focus With over 125 years of combined experience with small-scale, fully instrumented machines, KORSCH and MEDELPHARM have entered into a strategic partnership agreement focused on offering the most advanced line of R&D tablet compression technology in the world. The combined R&D product line meets and exceeds every requirement, from early-stage powder characterization and formulation development, to scale-up and production support. The new R&D line covers the full spectrum of tableting technology from single-layer to five-layer, as well as core coating....

Flexibility of Use The STYL’One Nano is a compact tabletop unit that can be installed on an existing bench, on its optional mobile base or even inside a downflow booth. It permits very small material quantities to be utilized and characterized very quickly with a minimum of setup. The machine is easy to clean due to a GMP working area featuring smooth surfaces and full accessibility. With a range of options and accessories the STYL’One Nano is a flexible research tool. Depending on future needs the machine can be retrofitted easily. Formulation development Formulation development Work with...

Advanced Instrumentation The STYL’One Nano is designed with the most advanced instrumentation to measure the upper and lower compression force and punch position. Mechanical deformation is automatically measured and compensated for by the software Standard Instrumentation Lower punch force (kN) Mimicking the Dwell Time (flat portion of punch head) Precompression Force Main Compression Force Upper punch force (kN) Ejection Force Upper Punch Displacement Lower punch position (mm) Lower Punch Displacement Material: Lubricated lactose – Main Pressure : 291 MPa (29 kN) – Punches: EU-B, round...

STYL’One Nano Benchtop Compaction Simulator Tableting has never been so easy to investigate, from pure API characterization to formulation assessment. The STYL’One Nano features not only all advantages of single-punch presses at formulation stage like an easy operation for small amounts of API but it also includes in a small footprint the unique and powerful drive technology, normally reserved for an Elite of premium compaction simulators. Scientists can use the flexibility to drive the punches at high velocity to replicate the pre- and main compression of an R&D rotary tablet press. The...

Powerful Software Platform Alix, installed on a laptop, guides the user step by step on a user-friendly interface. The software controls the STYL’One Nano, collects the data generated and analyzes the data by Control System Like the flagship STYL’One Evo, STYL’One Nano is entirely controlled by software. Each process parameter is precisely entered through a Human Machine Interface (HMI): Filling and dosing height orce, Pressure or Punch distance for precompression F and main compression Feeder parameters Number of tablets Data Acquisition and Analysis The HMI interface simplifies the design...

Efficient Analysis ALIX™ acquires all data in real time. Pre-defined USP <1062> plots for tablet characterization are natively integrated into STYL’One Nano software. Manufacturability profiles (tablet breaking force vs compression force) or tabletability profiles (tensile strength vs pressure) are readily available. Profiles Specific R&D Profiles: aw tooth = constant compression speed to characterize S API & Excipient or evaluate formulation. Largely used to analyze and standardize strain rate sensitivity tests (speed sensitivity). quare compression = extended dwell time for S...

Advanced Training he STYL’one Nano is a sophisticated compression data acquisition tool, and to ensure that the full capability of the T system can be realized, our teams of experts can provide advanced training to convey best practices for experimental design, data acquisition, data analysis and interpretation of the results. Characterize APIs & Excipients Formulation Development and Optimization Join the Community Enhance your tableting skills by joining MySTYL’One.com resource center and user community to share information and access a comprehensive library of STYL’One scientific...

STYL’One Nano Machine Specifications Description Punch Stations Punch Type Die Type Max. Production Output Compression Mode Force or displacement driven Upper Punch Penetration Depth Max. Main Compression Force Load Application Lower Punch Velocity Lower Punch Acceleration Dwell Time Tablet Format Single-layer only Power Supply Voltage Peak Power Electric Protection Fault Current Protection Compressed Air Weight Load distribution Technical modifications reserved. The technical specifications included in this document represent optimal parameters and are dependent on product quality and...

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