Pharmaceutical Rotary Tablet Press

Innovations Made in Berlin Since 1919 Focus Drives Perfection Specialization is the key. Since 1919, KORSCH has focused on its core competency of tablet compression technology. This focus and resulting experience base is the foundation for the broadest and most innovative product line for tablet compression technology. KORSCH offers an optimal solution for virtually every tablet compression application – through initial feasibility, research, scale-up, clinical production, and full scale 24/7 production. KORSCH presses are used successfully all over the world and are supported by a global network...

Two Machine Models … The XL 400 design offers a single-layer only, and a flexible single and multi-layer capability in two machine models that share a common platform, and fully interchangeable compo- nents. Depending on your product portfolio, you can select the SFP or MFP or combine both models and benefit from their common advantages and maximized compatibility. Dedicated High-Speed Single-Layer Production Discharge Chute MFP Flexible Single & Multi-Layer Production

… One Common XL 400 Platform The XL 400 platform permits complete turret and spare parts compatibility between the SFP and the MFP models. The SFP and MFP share an identical control system and HMI environment, and a process equivalent design to permit the transfer of single-layer products between machines. The SFP and MFP share common procedures for setup, changeover, and turret exchange. XL 400 SFP, Maximum Efficiency for Single-Layer Production Offering a 100 kN pre and main compression capability, 120 RPM press speed capability, and an extended feeder length, the SFP is geared for high-speed...

Common Platform for Enhanced Compatibility Functional Design Maximizes Productivity Optimal Control, User Friendly HMI, Fully 21 CFR Part 11 Compliant

Functional Design Maximizes Productivity The KORSCH design makes optimal use of the pitch circle – from die filling to tablet ejection. The strategic placement of all major components in the rear cabinet, and the open compression zone design, offers superior access for operation, cleaning, changeover, and maintenance. The isolation of the carrier plate virtually eliminates vibration and noise generation, and minimal parts are required for dis­ assembly and setup. The result is a streamlined design and an extremely efficient changeover process. Superior Accessibility to Compression Zone The...

Minimal Noise and Vibration The unique and patented design of the carrier plate, with ■ Very low noise emission <75 dB(A) pneumatic dampers, fully isolates vibration from the head piece and machine base. ■ No vibration transmission to the floor of the compression room The result is an extreme reduction in operating noise level, even with high compression forces and high press speeds. ■ No segregation of powder in the feeding system which can occur with machine vibration

Optimal Control, User Friendly HMI, Fully 21 CFR Part 11 Compliant KORSCH controls are based on a standard Siemens or Allen- standards, including WinCC and WonderWare, which are Bradley PLC. The touch screen HMI also uses industry operating on an industrial PC platform. User friendly touch screen control The main screen presents all important press parameters in a graphical format. The language may be changed at the push of a button. ■ Press force control KORSCH controls permit full compliance with 21 CFR Part 11. ■ Password login with four access levels ■ Electronic audit trails (event log,...

Special Features The XL 400 offers a range of special features, including: igh containment and wash-in-place execution H (WipCon®) including peripheral equipment for OEB 5 containment applications (< 0.1 µg/m³) edium containment (OEB 3) execution for hormone M production eep fill (28 mm) for lollipop execution, tablet thickness D to 14.5 mm Micro-chip-in-tablet capability

KORSCH 24/7 Service Helpline: Phone: +49 (0)30 43576-300 E-Mail: [email protected] KORSCH America Inc. 18 Bristol Drive South Easton, MA 02375 USA Phone: +1 (508) 238-9080 Fax: +1 (508) 238-9487 E-Mail: [email protected] KORSCH AG – Berlin Breitenbachstraße 1 13509 Berlin Germany Phone: +49 (0)30 43576-0 Fax: +49 (0)30 43576-350 E-Mail: berlin@korsch.

Pharmaceutical Rotary Tablet Press

Technical Data KORSCH XL 400 1-/2-/3-Layer Number of punch stations Main Compression Force Precompression Force Tamping Force Filling Depth, Second and Third Layer max. Turret Speed, Single-Layer Turret Speed, Bi-Layer Turret Speed, Tri-Layer Tablet Output, Single-Layer max. Tablet Output, Bi-Layer max. Tablet Output, Tri-Layer max. Pitch Circle Diameter Tablet Thickness Press Tools Machine Dimensions Net Weight of the Machine Electrical Load 1,605 x 950 x 2,200 – Dimensions are identical for all Versions Technichal modifications reserved. The maximum compression force varies as a function of...