SB200-X (OrbShake) Orbital shaken bioreactor for disposable bags

2 ᕡ Disposable bag with pH & DO sensors and various ports The SB200-X is an orbital shaken bioreactor for the cultivation of human, mammalian and plant cells in a disposable bag. A working volume from 50 litres up to 200 litres for the SB200-X ensures easy scale-up from microtiter plates to shaking flasks and all the way up to 200 litres. This user friendly system can be easily deployed in research, process development or production. Performance characteristics + Large capacity (200L working volume) + + + + single use bioreactor system Cultivation of human, mammalian and plant cells Fast, simple...

ᕢ Reader Box-X: Online measurement of pH and DO SB200-X (OrbShake) | 3 ᕣ Filter heater Trouble free scale-up Another advantage of the SB200-X is easy scale-up from microtiter plates all the way up to 200 litres. The consistent hydro-dynamics of shaken bioreactors provide reproducible cultivation conditions throughout the volume range. Control unit and online measurement The bespoke control unit, designed by Kuhner, uses the latest touch-screen technology and ISIS-X 8.0 software for data recording, calibration, programming and controlling. Technical controls for 21 CFR Part 11 compliance are built...

Shaken bioreactor • Order number Shaker speed Shaker diameter Weight approx. 400 kg without liquid Active brake adjustable Cooling cooling coils are incorporated cooling system (pressure <0.2bar) • Mains connection Capacity 2 exhaust filters Temperature range Ambient temperature up to 70°C, Oxygen Sensor Opt'ca' measuring method pH Sensor Opt'ca' measuring method Accuracy ± 0.05 pH at pH 7 with one point calibration

Control unit with touchscreen monitor, ISIS-Software, pumps & gas mixing device • Order number Weight 15’’ touchscreen monitor for monitoring, calibration, controlling O2, pH, shaking speed, temperature one point recalibration is possible 21 CFR Part 11 compliance (audit trail) Maximum Speed Maximum Speed Delivery Pressure Delivery Pressure Flow rates (ml/min at 100rpm) Flow rates (ml/min at 100rpm)

Mixing up to four gases Gas mixtures can also be connected Number of mass flow controllers 4 Input up to 4 gases, push in connector [6 mm] (air, oxygen, nitrogen, carbon dioxide) (gas mixtures can also be connected) Output 1, (tube fitting for tube ID 13 [mm]) Flow rate 0 - 20 [sL/min] Accuracy ±1.5% from the end value Pressure sensor integrated, 0-400 [mbar], programmable prevents over pressure in the connected vessel prevents blocking the mass flow controllers Back pressure valve integrated, prevents reflux into the mass flow controllers Controlled filter heating box for the outlet filters,...

SB200-X (OrbShake) | 7 ᕧ Tubing support bar Options Cooling The SB200-X has a cooling ring embedded in the base plate. Cooling is achieved by connecting an external cooling device. An integrated valve, controlled by the ISIS-Software, regulates the set point temperature. IQ-OQ Documentation IQ-OQ (Installation Qualification and Operation Qualification) is an equipment qualification required for GMPprocedures. Documentation is available from Kuhner and Qualification services can also be provided at the customer`s premises. Tubing support bar ᕧ Order number: SMX714001 A tubing support bar is available...

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