THE ESSENTIALS IN BONE GRAFTING BRIDGING MEDICAL GAPS

FAST FACTS • Clean and sterile, free of human, animal and chemical material. • Products can be custom ordered, ranging from pastes and cements to granulations and wedges. • No harvesting, so less risk of infections or complications. BONE GRAFTING AND BEYOND Kyeron believes in the future of bone grafting. We develop our products from a mineral basis. This will give you equal to superior results, comparable with the [human and synthetic] alternatives. Human when necessary, Kyeron when possible. This brochure will show you w

FAST FACTS • Worldwide distribution network. • Materials with superior handling. • Products can be custom ordered per unit. KYERON THE NEW GOLD STANDARD Kyeron performs in line with your expectations of a Our products do not take over functions. On the young independent player in the world of biomaterials. contrary, we want to activate the body and stimulate it We develop products with added value for surgery, to create bone cells itself. This places resorption at the with ample scope for our ideas and initiatives. centre of our broad spectrum. We develop granules, For science has not reached...

FAST FACTS • The University of Twente employs 3,000 academic researchers, a number of which are working fulltime on Kyeron projects. • We are established in the most entrepreneurial high-tech region of the Netherlands, close to one of the world’s leading nanotechnology laboratories. • Kyeron has an excellent quality assurance system in place and is ISO 13485 certifi ed by BSI. We consider the development of our resorbable innovations from the surgeon’s perspective. Kyeron operates a network of distributors, who are present at surgeries in hospitals all over the globe. Any obstacles a physician...

THE FUTURE OF BONE GRAFTING. What sets Kyeron apart, is the way we approach the composition of a granulate, paste or cement. FAST FACTS • Since 2007, hundreds of thousands of procedures have been carried out with our products on mineral basis. • The number of recalls of our products is zero. • Kyeron contributes worldwide to affordable and improved healthcare. We have for example introduced synergy between minerals, such as hydroxyapetite [HA], collagens, biopolymers and tricalcium phosphate [TCP]. And even with these high standards, our products are three to four times more cost-effective than...

HA/TCP GRANULES With HA/TCP GRANULES , Kyeron offers a substantiated alternative for autograft and • An HA with a Ca/P ratio of 1.76, identical to human bone apatite. allograft. It provides you with a biocompatible and osteoconductive material, without the need of We cannot fully inform you in this concise brochure. harvesting or the use expensive donor material - We merely want to draw your attention to the products with all related risks of rejection. HA/TCP with which we shape the future of bone grafting. GRANULES is composed of (40%) b-tricalcium phosphate and of (60%) hydroxyapetite. This...

“THE STERILE ALTERNATIVE T FOR AUTOGRAFT OR ALLOGRAFT” AUTOG Biomaterials have become a very active area of research and development worldwide. According to the surgical uses, biomaterials with a variety of properties have become available, each with their advantages and disadvantages. The importance of ceramics is evident due to their biocompatibility and because an important part of bones themselves are mineral phases. The mineral phase of the bone is mainly made up of calcium phosphate micro-crystals, among them hydroxyapatite (HA) is the most important. Specialists realized that the porous...

“BIOTISSUE SUBSTITUTE FROM PURE NANOHYDROXYAPETITE” BIOCOMPATIBILITY In the past decades, the elements of NANO HA PASTE nanohydroxyapatite (water and hydroxyapetite) have been generally recognised for their excellent biocompatibility and bioactivity. NANO HA PASTE possesses strongly-improved characteristics such as stability, natural resorption speed, good biocompatibility, improved osteogenesis and it is pH-neutral. NANO HA PASTE is known for its excellent response to biological elements. Bone ingrowth and bone formation around the hydroxyapatite crystals are excellent and the hydroxyapatite...

NANO HA PASTE NANO HA PASTE is the ready-to-use nano bone NANO HA PASTE is standard available in a broad graft substitute by Kyeron. It is an injectable paste for fi lling and repairing small to mediumsized bone defects. We cannot fully inform you in this concise brochure. We merely want to draw your attention to the products What makes NANO HA PASTE stand out, is the with which we shape the future of bone grafting. resorbable nanocrystalline structure. Moreover, the paste is non-load-bearing and will not harden once injected. We have succeeded in adding a unique NANO HA PASTE and our other products....

AXOZ QS CAP CEMENT The three essential characteristics for an injectable bone substitute coincide in AXOZ QS®: a cement with resistance under compression close to cancellous bone, a composition similar to the natural bone crystals and with unique “INJECTABLE CALCIUM PHOSPHATE THAT HARDENS QUICKLY AND FULLY RESORBS” macroporous injectable patented technology. AXOZ QS ® consists of resorbable phosphocalcic compounds and a polymer. A convenient product to work with, developed for the optimal recovery of bone defects. A number of important fi gures: • Preparations at the operating table take only...

FAST FACTS • Full range of micro, meso and macro pore sizes to promote bone cells colonization and biological fluid penetration. Decisive for the resorption of the cement thanks to the high porosity up to 70% porous. • Optimal processing thanks to the simple mixing process. • Kyeron products are worldwide certifi ed by among others the European CE, Australian TGA and Argentinian ANMAT. THE NEW STANDARD FOR BONE GRAFTING Since both allograft and autograft have drawbacks, a quest is out for materials that could be used in place of the transplanted bone. One day a substitute will simultaneously be...