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Bone regeneration material

Bone regeneration material

Bone regeneration material

Product catalog summary
Indications: OssaBase-HA is used in orthopedics and periodontology for procedures such as alveolar ridge remodeling, treatment of periodontal and bone defects, sinus lifts, and filling bone defects post-surgery to prevent atrophy.
Material Characteristics: OssaBase-HA is a synthetic, macro- and nanoporous bone regeneration material based on hydroxyapatite. It features up to 83% interconnected porosity, supporting vascularized bone formation and long-term graft stability. It mimics the structure of biological bone apatite and offers a synthetic alternative to bovine-derived substitutes.
Specifications: The material has a Ca/P molar ratio of 1.65, with granule sizes ranging from 0.3 to 2.0 mm and macropores greater than 100 μm. It has a specific surface area of 78.3 m²/g.
Advantages: OssaBase-HA's interconnected macro- and nanopores mimic human bone structure, providing excellent osteoconductive properties. It is fully synthetic, eliminating risks of immunological reactions or pathogen transmission. The material's high surface area and non-irritating shape facilitate easy preparation for implant insertion.
Osteoconductive Properties: The material demonstrates excellent osteoconductivity, with new bone formation observed at 3 and 6 months post-implantation. High magnification images show new bone forming around and within the material's macropores.
Comparison with Bio-Oss®: OssaBase-HA offers a similar structure and chemical composition to biological bone apatite and can substitute for non-sintered bovine apatite like Bio-Oss®, without the risk of antigenic proteins.
Experimental Data: Graphs show the correlation between total bone volume and healing time, comparing OssaBase-HA with Bio-Oss® and other materials, highlighting its effectiveness in bone regeneration.
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Catalog excerpts

Bone regeneration material-1

Bone regeneration material

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Bone regeneration material-2

OssaBase-HA  Macro and nano bone-like structure  Excellent volume maintenance  Low substitution rate OssaBase-HA is a synthetic, macro- and nanoporous bone regeneration material based on hydroxyapatite with a low substitution rate. It is used for the bone regeneration of missing or lost bone tissue independently, or in combination with autologous bone tissue, blood or PRP . OssaBase-HA features up to 83% interconnected porosity to support vascularized bone formation. Its low substitution rate helps to provide long-term graft stability and the maintenance of volume when a longer healing time...

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Bone regeneration material-3

OssaBase-HA ADVANTAGES OF OssaBase-HA • Structure system of interconnected macro- and nanopores which mimic the structure of human bone. • Excellent osteoconductive properties of OssaBase-HA enable predictable bone regeneration. • Optimal non-irritating shape of polygonal macro- and nanoporous granules. • High surface area typical for natural bone due to the network of nanopores. This nanostructure allows easy preparation by cutting instruments during later implant insertion. • No organic porogen compounds used during manufacturing – ensures particularly high chemical and phase purity. • Fully...

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Bone regeneration material-4

COMPARISON OF EXPERIMENTAL RESULTS OF OssaBase-HA AND PUBLISHED DATA OF Bio-Oss® The synthetic, porous B-type carbonated apatite prepared by low-temperature synthesis OssaBase-HA resembles the structure and chemical composition of the biological bone apatite and can substitute successfully for non-sintered bovine apatite prepared by the deproteinization of bovine bone (Bio-Oss®) with the advantage of the absolute elimination of risk associated with residual antigenic proteins of xenogeneic bone. 90 Specific surface areas (m2/g) TBV – Total Bone Volume % OssaBase-HA, experimental data Bio-Oss®,...

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