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Aperio LIS Connectivity Overview

Aperio LIS Connectivity Overview

Product catalog summary

Introduction
This document provides an overview of the Aperio LIS Connectivity, detailing its features, system design, and product capabilities. It serves as a guide for users to understand the integration and operation of Aperio systems with Laboratory Information Systems (LIS).

Product Overview
The Aperio LIS Connectivity facilitates the integration of Aperio eSlide Manager with LIS, enabling efficient data exchange and workflow management. Key features include support for HL7 messaging, various workflow configurations, and detailed system design specifications.

System Design
The system supports multiple workflows, including 'Order First Scan Next' and 'Scan First Order Next'. It allows for manual deletion of slides within the Aperio eSlide Manager. The design includes detailed message types and configurations to ensure seamless integration.

Product Capabilities
The integration engine supports various HL7 versions and is designed to operate in diverse environments. Licensing and key configurations are outlined to ensure compliance and optimal performance.

Technical Specifications
The document includes a comprehensive technical specification section, detailing HL7 message structures, clinical, research, and educational hierarchies, and specific scenarios for order management and cancellation.

Contact Information
For technical support and customer service, contact details for various countries are provided, ensuring users can access assistance as needed.

Workflows
Order First Scan Next Workflow: Initiates scan order from LIS, saving data in Aperio eSlide Manager. The workflow involves barcode scanning and image storage, with viewing links provided for user access.
Scan First Order Next Workflow: Begins with slide scanning, followed by order sharing from LIS. Images are associated with incoming cases, and viewing links are provided.
Manual Deletion Workflow: Describes the process when slides are manually deleted in Aperio eSlide Manager, triggering a delete message to LIS.

Additional Features
Security is ensured through user authentication and encrypted information exchange. The installation process is automated, requiring minimal configuration.

Protocol Definition
HL7 and SOAP/XML are the primary protocols used for data transfer between healthcare software applications.

Message Types
The system uses various HL7 message types, such as OML^021 for incoming orders and OUL^R21 for slide registration responses.

Integration Engine
Aperio LIS Connectivity employs NextGen Connect for message transformations, supporting HL7 2.x versions. It requires configuration of IP addresses and ports.

Environment Description
The system is installed alongside Aperio eSlide Manager, allowing remote access via VPN or DMZ. It maintains logs for traceability.

Licensing
A perpetual license is used, dependent on the availability of the Aperio eSlide Manager license.

Data Group
The DataGroup field in HL7 messages authorizes user access, with configurable behavior based on its presence or absence.

HL7 Overview
HL7 messages consist of segments and fields, separated by specific characters. The document provides examples of message formats for different order types, including new, update, and cancel orders at various hierarchy levels.

Technical Specification
Sample HL7 messages are provided for clinical and research hierarchies, illustrating the structure and content of messages exchanged between systems.

Specifications
The document specifies the HL7 message types used for communication between LIS and Aperio eSlide Manager, including New Order, Update Order, and Cancel Order. It details the expected behavior for each message type, such as creating, updating, or deleting records at various hierarchy levels (Case, Project, Course, Lesson, Specimen, Block, or Slide).

Procedures
The document describes the workflow for processing orders and specimens, including the creation and management of slide records. It highlights the importance of unique identification for cases and specimens to ensure accurate processing and tracking.

Standards and Recommendations
The document emphasizes adherence to HL7 standards for message formatting and communication. It recommends best practices for managing slide and specimen data, including the use of unique identifiers and maintaining accurate records.

Data Interpretation
The document includes references to various data types and formats, such as URLs for accessing slide images, Base64 encoded data for labels and macros, and specific staining techniques like Periodic Acid Stain (PAS).

Critical Information
The document highlights the importance of maintaining accurate and up-to-date records for specimens and slides. It stresses the need for seamless integration between LIS and Aperio eSlide Manager to ensure efficient laboratory operations.

Mapping Details
Detailed mapping information is provided for each hierarchy, specifying required and optional HL7 fields, their corresponding Aperio eSlide Manager fields, and expected values or constraints. This includes field separators, encoding characters, message types, and control IDs, among others.

Key Data from Tables
The tables in the document provide a detailed breakdown of HL7 fields, their necessity, corresponding Aperio eSlide Manager fields, and constraints for Clinical, Research, and Educational hierarchies. These tables serve as a reference for ensuring correct message formatting and data integration.

Technical Specifications Overview
The document provides a comprehensive overview of the Aperio LIS Connectivity, focusing on the technical specifications required for integration with the eSlide Manager. It includes details on image data formats, HL7 message structures, and custom field configurations.

Image Data Specifications
Various image data types are specified, including macro, report, and thumbnail images, all encoded in base64. The document outlines the expected formats for dates and scan scope IDs, emphasizing the importance of correct data types and constraints.

Custom Fields
Custom fields must be pre-configured in the Data Server database. The document outlines the syntax for custom fields and provides examples for different hierarchy levels, such as Slide, Block, Specimen, Lesson, Course, Project, and Case.

URL Encoding for Viewer Links
The document describes the format for URL links used to display eSlide images in WebViewer or ImageScope. It includes a table of special characters and their encoded values to ensure proper URL formatting.

Symbols and Safety Instructions
The document includes a section on symbols that may appear on product labels, providing explanations for each symbol related to safety and operational instructions.

Catalog excerpts

Aperio LIS Connectivity Overview

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Aperio LIS Connectivity Overview Copyright Notice Ì Copyright © 2020-2022 Leica Biosystems Imaging, Inc. All Rights Reserved. LEICA and the Leica logo are registered trademarks of Leica Microsystems IR GmbH. Aperio is a trademark of the Leica Biosystems group of companies in the USA and optionally in other countries. Other logos, product and/or company names might be trademarks of their respective owners. Ì product is protected by registered patents. For a list of patents, contact Leica Biosystems. This Customer Resources Ì the latest information on Leica Biosystems Aperio products and services,...

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Customer Service Contacts Please contact the office for your country for technical assistance. 96 Ricketts Road Mount Waverly, VIC 3149 AUSTRALIA Tel: 1800 625 286 (toll free) Between 8:30 AM-5 PM, Monday-Friday, AEST Email: [email protected] Leica Biosystems Nussloch GmbH Technical Assistance Center Heidelberger Strasse 17 Nussloch 69226 GERMANY Tel: 0080052700527 (toll free) In-country Tel: +43 1 486 80 50 50 Email: [email protected] Tel: 0080052700527 (toll free) In-country Tel: +32 2 790 98 50 Email: [email protected] Tel: +1 844 534 2262 (toll...

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96 Ricketts Road Mount Waverly, VIC 3149 AUSTRALIA Tel: 0800 400 589 (toll free) Between 8:30 AM-5 PM, Monday-Friday, AEST Email: [email protected] Tel: 0080052700527 (toll free) In-country Tel: +35 1 21 388 9112 Email: [email protected] BioLine LLC Pinsky lane 3 letter A Saint Petersburg 197101 THE RUSSIAN FEDERATION Tel: 8-800-555-49-40 (toll free) In-country Tel: +7 812 320 49 49 Email: [email protected] Tel: 0080052700527 (toll free) In-country Tel: +46 8 625 45 45 Email: [email protected] Tel: 0080052700527 (toll free) In-country Tel: +41 71 726...

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Aperio LIS Connectivity Overview, Revision C © Leica Biosystems Imaging, Inc. 2022

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Aperio LIS Connectivity Overview, Revision C © Leica Biosystems Imaging, Inc. 2022

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Aperio LIS Connectivity Overview, Revision C © Leica Biosystems Imaging, Inc. 2022

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This document provides an overview of the Aperio LIS Connectivity solution, showing how it helps to integrate your Laboratory Information System (LIS) with Aperio eSlide Manager, a digital slide management system. We discuss the features of Aperio LIS Connectivity, the benefits it provides, and how it optimizes the efficiency of your user workflow. IT Managers may find this document helpful in explaining how Aperio LIS Connectivity fits into their network environment, and how it connects the LIS and Aperio eSlide Manager to provide an integrated solution. About This Guide ` This chapter contains...

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Figure 1: Overview of the Integration System Above is a simple representation of what the integration looks like. Aperio LIS Connectivity offers bi-directional messaging between the LIS and Aperio eSlide Manager. Aperio LIS Connectivity is responsible for handling message transformations between the systems. In other words, Aperio LIS Connectivity accepts information from the LIS through HL7 2.x messages, internally transforms that using Leica-Aperio eSlide Manager specifications, and transmits the data to Aperio eSlide Manager to save in its database. Conversely, when physical slides are scanned...

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Figure 3: Aperio LIS Connectivity Solution Benefit Additional Features Other benefits of Aperio LIS Connectivity include: ` To avoid unauthorized access, users accessing the system are authenticated and authorized through Aperio eSlide Manager credentials while accessing the digital slide viewer. ` Information exchange between systems is encrypted so that there is no misuse of patient information while information is being transfered between Aperio eSlide Manager and the LIS. ` Aperio LIS Connectivity installations are automated with minimal configuration, which saves time and enables a quicker...

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System Design Figure 4: Overall System Design The illustration above shows how Aperio LIS Connectivity fits into your system. Aperio LIS Connectivity Overview, Revision C © Leica Biosystems Imaging, Inc. 2022

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Workflows This section shows different workflows supported by Aperio LIS Connectivity. Order First Scan Next Workflow Figure 5: Order First Scan Next Workflow The Order First Scan Next Workflow initiates the scan order request from the LIS. The data from the order gets saved in Aperio eSlide Manager as Case, Specimen, Cassette/Block, and/or Slide in the Clinical hierarchy; as Project, Specimen, Cassette/Block and/or Slide in the Research hierarchy; and as Course, Lesson, Specimen, Cassette/Block and/or Slide in the Educational hierarchy for orders. The scan response only triggers if the slide...

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project, course, lesson, specimen, cassette/block or slide record is married up to scanned image by way of the decoded slide barcode. 4. Viewing (URL) links are now available for case, project, course, lesson, specimen, cassette/block or slide level and are sent from the Aperio eSlide Manager interface to the LIS. 5. If the Viewing link is available in the LIS the user selects the link which will open in the web browser (Chrome or Internet Explorer) the Aperio eSlide Manager login screen and subsequently the Slide image(s). With the slide images now viewable the Pathologist/User reviews the slide...

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1. LIS user enters slide order into the LIS. Using the LIS or equivalent system the user prints labeling information to the slide including the slide identifier barcode. 2. Aperio Scanner decodes barcode and captures image. (All Aperio scanners can be represented in this workflow) Slide image is stored in the Aperio eSlide Manager image location. 3. A parent Slide record is created from the barcode ID for the captured slide image. A slide level response message with optional slide level URL can be sent to the LIS. 4. The LIS processes the slide level response message and subsequently sends a...

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Detailed Design Figure 8: Detailed System Design The detailed design diagram above illustrates the components of Aperio LIS Connectivity, the mode of communication between the components, and the standard ports they use for transporting information. NextGen Connect is a cross-platform interface engine that validates, accepts and relays portable messages between Sync Hub and the LIS. All communications marked with green arrows are secure using TLS v1.2. All communications marked with orange arrows are configurable for cybersecurity. If the LIS vendor’s LIS is not SSL compatible, we recommend the...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.

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