THUNDER Imager Live Cell

Product catalog summary

Overview
The THUNDER Imager is a cutting-edge imaging system designed for advanced 3D cell culture assays, including live cell imaging, stem cells, spheroids, and organoids. It utilizes Computational Clearing technology to eliminate out-of-focus blur, enhancing imaging speed, sensitivity, and ease-of-use typical of widefield microscopes.

Key Features

High throughput for improved statistics and efficiency.
High imaging performance with user-friendly operation.
Optimal physiological conditions for meaningful results.
High-speed positioning with Quantum stage and Synapse real-time control.
High-speed illumination with optional multi-line LED light source.
High sensitivity due to sCMOS technology and Leica optics.
Efficient removal of out-of-focus blur, even in single plane acquisitions.
Compatibility with multi-well carriers for automated water immersion, enhancing sensitivity and resolution.

Applications
The THUNDER Imager is suitable for modern sample carrier formats like 8-chamber slides or 96-well plates, allowing for more data generation in less time. It is designed to meet the needs of future 3D cell culture applications by minimizing light exposure and providing brilliant images.

Contact Information
Leica Microsystems CMS GmbH, Ernst-Leitz-Strasse 17–37, D-35578 Wetzlar, Germany. Tel: +49 (0) 6441 29-0, Fax: +49 (0) 6441 29-2599, Website: www.leica-microsystems.com/thunder

Catalog excerpts

THUNDER Imager 3D Live Cell, 3D Cell Culture & 3D Assay Decode 3D Biology in Real Time* Cultured Cortical Neurons. Green: beta-III-tubulin; blue: Nuclei. Image stack of 59 planes of a volume of 21µm was acquired using a THUNDER Imager 3D Cell Culture. Sample courtesy FAN GmbH, Magdeburg(Germany). THUNDER Imagers offer you a solution for advanced 3D cell culture assays, whether you work with stem cells, spheroids, or organoids. THUNDER Imagers remove the out-of-focus blur that comes with three-dimensional samples through Computational Clearing, an exclusive new breakthrough technology. You still benefit from the imaging speed, sensitivity, and ease-of-use common to widefield microscopes. With a THUNDER Imager for 3D Live Cell & 3D Cell Culture, you have these advantages: >> High throughput for better statistics and efficiency >> High imaging performance from an easy-to-use instrument >> Optimal physiological conditions for meaningful results The THUNDER Imager 3D Live Cell, 3D Cell Culture & 3D Assay are part of the THUNDER family of imaging systems. Cultured cortical neurons. Red: anti-GFAP-Alexa568 (astrocytes); cyan: DAPI (nuclei); purple: anti-betaIII-tubulin-Alexa488 (mature cortical neurons). Z-stack of 59 planes (thickness: 21µm). Sample courtesy FAN GmbH. * in accordance with ISO/IEC 2382:2015

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Copyright © by Leica Microsystems CMS GmbH, Wetzlar, Germany, 2019· Subject to modifications LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH. Advance your live cell imaging to a whole new level optimized for specimens of physiological relevance THUNDER Imager is designed to meet the needs of tomorrow’s 3D cell culture applications. Work effortlessly with modern sample carrier formats, such as 8-chamber slides or 96-well plates. Generate more data in less time to boost the statistical power of your assay. Get closer to observing the real physiology of your 3D specimens...

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