Nano+™ Polymer-Free Sirolimus-Eluting Coronary Stent System Product Information Nothing Beats Free New Delivery System 0.017" soft tapered tip Short and round shoulder Hydrosurf ™ hydrophilic coating • olymer-free DES P • anoporous drug carrier on N abluminal surface • Balanced strut thickness • igh radial force H • ine wave + 3-3-3 link S • ouble helix structure D • arge open cell L • recise positioning markers P • Effective drug of Sirolimus • acuum drug coating technology V • 0-day drug releasing period 9 • ew delivery system N Vacuum Drug Coating Technology Ensure complete drug dosage and coating stability Nanoporous Drug Carrier on Abluminal Surface Nanoporous After Drug Loaded Ave. Pore Diameter: 400nm Ave. Pore Depth: 150nm • Significantly shorten DAPT time • Earlier & better endothelialization • Highly reduced risk of thrombosis • Great deliverability • Easy positioning and placement • Optimal tissue scaffolding • Excellent side branch access • Scientific drug releasing period Smaller cavity has stronger adhesion of drug Ranges Normal Drug Coating Technology • Ø 2.5 - 4.0 mm • 12 - 36 mm multi stent lengths Lumen Loss of Nano+ TM Lumen Loss of Durable Polymer SES Inflammation of Durable Polymer SES 1 Month Animal Experiment Result: HE Staining of Nano+ TM Sten

Nano+™ OCT Study [3] An OCT Study in Europe Shows Nano+™ A Great Combination of DES Efficacy and BMS Safety No binary restenosis in-stent and in-segment at 6 months No malapposed struts at 6 months Covered struts at 6 months No definite, probable or possible stent thrombosis at 24 months Technical Parameters Stent Material Strut Design Strut Thickness Metal-artery Ratio Recoil Ratio Shorting Ratio Lowest Crossing Profile Balloon Tip Profile Delivery System 316L Stainless Steel Nanoporous drug carrier on abluminal surface 91 15% < 2% < 1% 0.035" (0.90mm) 0.017" RX [3] Suwannasom, P., et al. "Evaluation...