INSPIRE® OXYGENATOR FAMILY Optimised, powerful perfusion Minimized impact on hemodilution thanks to the low dynamic operating volume (DOV) Effective gaseous microemboli (GME) handling Enhanced biocompatibility - The unique design of the Dual Reservoir ensures activated suction blood sequestration. This, in combination with an uniform biocompatible surface treatment that feature phosphorylcholine (PC)1,2 1) Albes JM, et al. Physiological coagulation can be maintained in extracorporeal circulation by means of shed blood separation and coating. J Thorac Cardiovasc Surg 2003;126:1504–12 2) Shann KG, et al. An evidence-based review of the practice of cardiopulmonary bypass in adults: a focus on neurologic injury, glycemic control, hemodilution, and the inflammatory response. J Thorac Cardiovasc Surg 2006;132:283

INSPIRE®: offering the most complete range of flow sizes to meet adult oxygenation needs Leveraging a worldwide leadership LivaNova products for cardiopulmonary bypass have helped clinicians provide safe and effective perfusion for more than 40 years. INSPIRE® is a complete family of adult oxygenators designed from years of research and laboratory experience, input from clinical experts from around the world and the application of advanced manufacturing technologies that adhere to the highest quality standards. When designing INSPIRE®, our vision was to raise performance expectations and ease...

Designed to Meet All Adult Patient Perfusion Needs and Practices 1 Effective gaseous microemboli (GME) handling Minimized impact on hemodilution thanks to the low dynamic operating volume (DOV) Designed for effective air management The combination of the geometry of the Inspire HVR/HVR Dual and the two-step venous filters contributes to a further reduction in hemodilution and an efficient air handling. INSPIRE® is designed to minimize hemodilution, which can in turn lead to a reduction in blood transfusions and post-op Acute Kidney Injury (AKI)1 INSPIRE® devices are characterized by the lowest...

Enhanced Biocompatibility 0 LivaNova has designed an uniform biocompatible surface treatment that feature phosphorylcholine (PC). 0 INSPIRE® Dual is the only hard-shell venous reservoir that allows activated suction blood separation. LivaNova products for cardiopulmonary bypass have helped clinicians provide safe and effective perfusion for more than 40 years. Adult patient population and oxygenator of choice 0 The unique design of the Dual Reservoir ensures activated suction blood sequestration. This, in combination with an uniform biocompatible surface treatment that feature phosphorylcholine...

INSPIRE® Oxygenators Flexibility and easy handling Compact oxygenator system requiring minimal storage space. 4.5 litre max. reservoir capacity volume. - 4 litre maximum operating volume. Maximal system rotational freedom. Port orientation, and system priming have been optimized to offer easy set-up and operational flexibility. The simple bracket design allows easy and fast mounting of the oxygenator system. Bracket is available with a regular screw clamp and fast lock mechanism. Inspire HVR and HVR Dual Hard shell venous reservoirs The Inspire hard-shell venous reservoirs are extracorporeal...

INSPIRE C - Gentle Perfusion Inspire C closed system helps reduce inflammatory response and improve biocompatibility.1 Unique integrated closed system oxygenator Designed to minimize impact on hemodilution Precise volume control Designed for effective air management, reducing gaseous micro-emboli (GME) Inspire C has the lowest minimum operating level among adult closed system reservoirs As a closed oxygenator system, Inspire C has reduced foreign surface area, no defoaming agents and no permanent air-to-blood interface. The integrated and versatile system offers wide choice of set-up options....

The top-purge efficiently handles air in most working conditions The deep-purge efficiently removes air when the squeezer is not in place or the reservoir is partly empty Inspire C has a unique fine adjustment parallel plate squeezer with continuous volume scale measurement. Set-up available with and without squeezer. When used without a squeezer, Inspire C allows simple free blood volume handling. Used with the squeezer, Inspire C : # enables full blood volume control # maximizes prime recovery prior to CPB # helps precisely manage the CPB weaning process The squeezer makes it possible to regulate...

Performance charts INSPIRE® 6 Dual PH.I.S.I.O. INSPIRE® 6F Dual PH.I.S.I.O. INSPIRE® 8 Dual PH.I.S.I.O. INSPIRE® 8F Dual PH.I.S.I.O. Test Conditions (Bovine blood - Hb 12±0.2 gr/dl - B.E. 0±2mEq/) – Venous pCO2 45±5 mmHg - 02 Venous Sat. 65±5% CONDITIONS – TEST Blood Temp. 37±1 °C - QG/QB=1 - Fi02 100% Bovine blood - Hb 12±0.2 gr/dl - B.E. 0±2mEq/l Qw=10±0,5 l/min) - Venous pCO 45±5 mmHg - O Venous Sat. 65±5% Test Conditions (Bovine blood - Hb 12±0.2 gr/dl - B.E. 0±2mEq/) – Venous pCO2 45±5 mmHg - 02 Venous Sat. 65±5% CONDITIONS – TEST Blood Temp. 37±1 °C - QG/QB=1 - Fi02 100% Bovine blood -...

Technical specifications INSPIRE® 6 Dual PH.I.S.I.O. Oxygenator System Oxygenator System INSPIRE® 8 Dual PH.I.S.I.O. Oxygenator System Oxygenator System - Oxygenator system DOV @ max flow - Biocompatible coating - Oxygenator system DOV @ max flow - Biocompatible coating - Oxygenator system DOV @ max flow 445 ml - Biocompatible coating Phosphorylcholine (PHISIO) - Oxygenator system DOV @ max flow 445 ml - Biocompatible coating Phosphorylcholine (PHISIO) Max. Volume Capacity (approx.) 4500 ml Max. Operating Level (approx.) 4000 ml

INSPIRE® order guide Integrated HVR INSPIRE® 6 LPM PHISIO OXY module with integrated arterial filter and PHISIO hard shell venous reservoir Accessories 050704 INSPIRE® HVR INSPIRE® PHISIO hard shell venous reservoir 050705 INSPIRE® HVR Dual INSPIRE® PHISIO dual hard shell venous reservoir 050706 INSPIRE® SVR 1200 INSPIRE® PHISIO 1200 soft shell venous reservoir Available only into PTS INSPIRE® 6 LPM PHISIO OXY module with integrated PHISIO 1200 soft shell venous reservoir Bracket for INSPIRE® OXY modules and integrated oxygenator systems with fast clamp INSPIRE® BKTH Bracket for INSPIRE® HVR...