NextGen Microfluidic Microtiter Plate Flexible BioProcess Control Continuous Feeding & pH Control High-Throughput Fermentation Flower-Shape or Round Well Geometry Real-Time Monitoring Scalability

Enhanced Bioprocess Control On-the-Plate Individually Fed and pH regulated Wells The NextGen Microfluidic Microtiter Plates facilitate high-throughput screening in up to 32 individually controllable cultivation wells. The proven technology of microscale feeding combined with non-invasive measurement of the most relevant fermentation parameters, e.g. biomass, as well as pH, DO and fluorescence, enables an industrially-tailored bioprocess development and its optimization. All 32 cultivation wells can be controlled individually through microvalves and microfluidic channels allowing for high-precision...

Microfluidic Microtiter Plates | m2p-labs Features Online Control • pH value • Feeding • Shaking speed • Temperature • Humidity • O2 in head space atmosphere • CO2 in head space atmosphere System performance • Proprietary flower shape or round well geometry • Working volume of 800 – 2400 µL • 32 parallel microreactors • 16 reservoir wells • Individual pH control (down to pH 4) • ontinuous individual feeding C • Broad range of kLa values (30 – 650 h-1) • calability to lab fermenters S • eeding modes: constant, linear, exponential F or signal-triggered Microbioreactors | NextGen Microfluidic Microtiter...

Feeding or pH control - 16 individual solutions The microfluidic microtiter plates provide the first two well rows as reservoirs for the desired feeding solutions, the remaining 32 wells work as distinct bioreactors. The task for each reservoir row can be chosen independently, either enabling the system to deliver two different feeding solutions, or one feed and one pH value up-/down-regulation, or two-sided, acid and base pH control for each well column. Constant, linear or exponential feeding can be chosen while a closed loop controller ensures proper pH control. Pressurized air actuates membrane...