Readers
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Readers Spot analysis reinvented Game-changing readers for FluoroSpot, ELISpot, and FociSpot Minimized variability Automated settings ensure unbiased analysis Load your plate and press “Read” – it’s that s

How do our readers work? To make plate reading and spot analysis effortless and reliable, we developed the Mabtech IRIS™ 2 and Mabtech ASTOR™ 2. Mabtech IRIS 2 supports FluoroSpot, ELISpot, and FociSpot analysis, while Mabtech ASTOR 2 is our ELISpot-only reader. Our readers offer a revolutionary approach to spot analysis. Simply select the assay, load the plate, and press read. Our patented RAWspot™ algorithm ensures highly accurate spot center detection and counting. The software Mabtech Apex™ provides a plug-andplay system that is incredibly user-friendly. With IRIS 2 and ASTOR 2, users...

What are the benefits? IRIS 2 is our premier reader for FluoroSpot, ELISpot, and FociSpot analysis. The reader can detect up to four analytes simultaneously with unparalleled accuracy and speed. ASTOR 2 is our workhorse, an ELISpot-only reader built to be fast and easy to use. Fixed focus, optimized default reader settings, and selfcalibrating XY table: We developed our readers to be as intuitive as possible, allowing you to get right to your data. Minimize subjective analysis Automated reader configurations and default analysis settings minimize subjective input, reducing operator bias....

Secretory profile of every cell Our RAWspot technology depicts the secretory profile of every cell to determine the exact spot center. This ensures reliable spot counts as well as accurate identification of multi-analyte secreting cells in FluoroSpot. RAWspot technology’s 3D model allows for a new type of data be generated in FluoroSpot and ELISpot: relative spot volume. Now you can measure the relative amount of secreted analyte per cell. Quick data acquisition An overlooked and time-consuming aspect of spot assays has been data analysis. With reliable data, a plug-and-play experience, and...

A new era of almost-too-easy Ready for automation Both readers are designed to make the analysis of larger projects as painless as possible. In addition to self-calibration, responsive software, and easy data handling, IRIS 2 and ASTOR 2 allow for robotic plate loading. Our readers can be part of an automated workflow with a robotic arm or be fully integrated into a larger automated setup. Each automation solution is unique, but we’ll be here for you every step of the way. Regulatory compliance The EU and the US (FDA) have established guidelines for the life sciences industry, known as...

Performance qualification Our readers are reliable tools that can be trusted to deliver accurate results over an extended period of use. However, it's essential to demonstrate that the readers maintain acceptable performance over time, especially when facing internal or external review for regulatory compliance. Mabtech's Performance Qualification (PQ) plates provide a solution for verifying that our instruments fulfill quality specifications and to ensure reproducibility. The PQ plates allow users to conduct a series of quantitative and qualitative tests making it easy to identify any...

Why spot analysis? Sensitive detection with ELISpot and FluoroSpot In ELISpot and FluoroSpot, the analytes of interest are captured directly upon secretion and throughout the stimulation process. This enables the analysis of physiologically relevant secretion. It’s also why these assays are considered extremely sensitive cellular assays. And high sensitivity means that ELISpot and FluoroSpot are particularly useful for studying rare cell populations that arise during specific immune responses. Analysis of physiologically relevant secretion Study up to four analytes with FluoroSpot...

Support you can rely on That’s the Mabtech way From product choice to data analysis – using our readers should be easy and self-explanatory. Nevertheless, if you do have questions, our team is here to provide technical support. Get in touch with us and we will find a solution for you. Service packages In addition to the included warranty, our instruments can be complemented with additional service packages to suit your specific needs. Get in touch with us or your local distributor for more details. Demo (onsite/online

Mabtech IRIS 2 and Mabtech ASTOR 2 are based on the same intuitive software and plug-and-play hardware. Each reader is built, calibrated, and validated at Mabtech's headquarters in Sweden.

Check out our readers For more information on our readers and other products, visit our website! Reader-related documents, publications, and highlighted research summaries are continuously updated. Get the full picture by visiting www.mabtech.com or scanning the QR-code. Selected references Our readers appear in numerous publications ranging from vaccine development to cancer research and autoimmunity. Scan the QR code for a full list of references. Bronge et al., Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis, Science Advances 2022...

About Mabtech Mabtech is a Swedish biotech company founded in 1986. Our mission is to aid scientists to reach new frontiers through optimal immunoassays and instruments.