Medi-Test urine analysis Easy urine analysis n Urine analysis with test strips n URYXXON® Relax Automated urine analysis at the point of care n URYXXON® 500 High performance urine analysis www.mn-net.com www.mn-net.com

The company Welcome to MACHEREY-NAGEL We are pleased that you are interested in our high-quality medical test strips. This brochure gives you an overview over our different products and applications in the field of urine analysis. Since its foundation in 1911, the roots of MACHEREY-NAGEL are the production of high-quality filter papers. Since the fifties, we have developed filter papers into top quality test papers for laboratory use. Today, we offer the world’s largest selection of different test papers. Additionally, we offer a versatile program of special products for analytical chemistry...

Urine analysis Urine analysis with test strips The use of urine test strips is acknowledged as a modern screening method in medical practice. With these non-invasive tests important information on the health status of patients is rapidly obtained. The urine sample is easily drawn and can be investigated immediately with a test strip. Thus one obtains results within minutes, which facilitates the decision on further diagnostic and therapeutic action. U rine test strips offer a rapid survey of a patient’s health status Urine chemistry – rapid and reliable F lexible strip design for small volume...

URYXXON® Relax Automated urine analysis at the point of care The URYXXON® Relax device provides dependable urine status results to detect early stages of many diseases such as diabetes, kidney disease and urinary tract infections. Instrument-read results have long proven to be advantageous for both busy health care professionals and patients. URYXXON® Relax readings eliminate the subjectivity of visual color interpretation. The comprehensive interface options and the optimized printouts minimize risks associated with manual transcriptions. Reliable results can be obtained immediately at the point...

URYXXON® 500 High performance urine analysis P erfect workflow usability The URYXXON® 500 is an automatic reader for URYXXON® Stick 10 urine test strips. With a capacity of 400 strips per hour, it is ideal for use in hospitals and practices. The “easy-to-use-features” allow hygienic operation with hardly any training. Compact design The URYXXON 500 provides dependable urine status results to detect early stages of many diseases such as urinary tract infection, kidney diseases or diabetes. The device eliminates the subjectivity of visual strip evaluation and minimizes risks associated with manual...

Significance of the parameters The medical context of urine parameters Urine test strips are indispensable tools in medical diagnostics to gain a rapid survey of the state of health of a patient. Blood: Serious infections of the kidneys and urinary tract, urolithiasis, suspected renal or bladder neoplasms Urobilinogen: Acute and chronic liver parenchyma damage, hemolytic jaundice, pathological state of the intestinal tract Bilirubin: Liver parenchyma damage, obstructive jaundice also for indicating biliary obstructions) Creatinine: To supplement the albumin factor and to create the albumin/creatinine...

Medical parameters – Principle, evaluation, sources of error, diagnosis Mikroalbumin: Principle: The test is based on the principle of the “protein error” of indicators, i. e. at a constantly buffered pH, albumin reacts with a tetrabromophenol sulphonephthalein derivative resulting in a color change from yellow-green to green-blue. Evaluation: The color fields correspond to the following concentrations of Albumin: 10, 30, 80 and 150 mg/L albumin Diagnosis: In combination with the test for creatinine, this test allows the calculation of the albumin / creatinine ratio using the interpretation table...

Medical parameters – Principle, evaluation, sources of error, diagnosis Urobilinogen Principle: The test paper contains a stable diazonium salt producing a reddish azo compound with urobilinogen. Evaluation: Depending on the urine color concentrations from 1 mg urobilinogen/dL urine are indicated. 1 mg/dL is considered to be the normal excretion rate. Higher values are pathological. A complete absence of urobilinogen in the urine, which is likewise pathological, cannot be detected with the strips. The color fields correspond to the following urobilinogen concentrations: Detection of liver diseases...

Medical parameters – Principle, evaluation, sources of error, diagnosis 3) enal proteinuria is caused by increased permeability of the glomerular filter and may R indicate pyelonephritis, glomerulonephritis, tuberculosis of the kidneys, kidneys participation at infections and poisonings, cystic kidneys, gouty kidney. Every positive test reaction requires further diagnostic examinations. Nitrite Principle: Microorganisms, which are able to reduce nitrate to nitrite, are indicated indirectly with this test, which is based on the principle of Griess reagent. The test paper contains an amine and...

Medical parameters – Principle, evaluation, sources of error, diagnosis An inhibitory effect is produced by gentisic acid. Falsely positive reactions can also be produced by a residue of peroxide-containing cleansing agents. The test is not influenced by vitamin C. Diagnosis: Because of the clear distinction between physiological and pathological glucosuria, the test is especially suitable for the detection of diabetes mellitus and for supervising (and self-supervising) of diabetes. Apart from diabetes mellitus, renal glucosuria with increased glucose concentrations may be noted during pregnancy,...

Medical parameters – Principle, evaluation, sources of error, diagnosis Leukocytes Principle: The test is based on the esterase activity of granulocytes. This enzyme splits a carboxylic acid ester. The alcohol component formed during this step reacts with a diazonium salt to form a violet dye. n S ymptomatic of renal and urinary tract diseases Evaluation: The test detects values from about 10 leukocytes/μL urine. Discolorations, which can no longer be correlated to the negative test field, and weakly violet discolorations after 120 seconds are to be considered positive. The color fields correspond...