MagSi-DNA mf MagSi-DNA mf COOH

Product catalog summary

Overview: The document describes MagSi-DNA mf and MagSi-DNA mf COOH, specialized magnetic beads designed for nucleic acid purification in microfluidic systems. These beads feature a unique magnetic core with a silica shell, offering a small bead diameter and a large active silica surface, which results in high yields and quality of nucleic acids.

Features:

Instant collection even in weak magnetic fields and easy resuspension.
Suitable for typical nucleic acid applications such as multiplex qPCR and LAMP.
Compatible with drying/reconstitution cycles for stable storage.
Applicable in MTP-based extraction processes and easily automated on liquid handlers.
Suitable for both DNA and RNA extraction.
Can be integrated into microfluidic platforms for point-of-care applications, with performance equal to or exceeding competitors.

DNA Extraction Process: The extraction process in microfluidic conditions mirrors traditional methods, relying on the reversible adsorption of nucleic acids to magnetic beads under specific buffer conditions. The process involves binding DNA to the beads, washing to remove contaminants, and eluting purified DNA for downstream applications. This method allows for significant cost reduction and faster protocols, facilitating the development of portable diagnostic devices.

Performance Comparison: The document includes a comparison of extraction kits using MagSi-DNA mf beads and competitor's beads on bacterial DNA, demonstrating no PCR inhibition with MagSi-DNA mf beads.

Product Information: The document lists product numbers and quantities for MagSi-DNA mf and MagSi-DNA mf COOH, available in 2 mL, 10 mL, and 100 mL volumes.

Catalog excerpts

MagSi-DNA mf MagSi-DNA mf COOH Nucleic Acid Purification in Micro fluidic Systems

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Microfluidics Microfluidics deals with the precise control and manipulation of fluids which are geometrically constrained to a small, typically sub-millimeter, scale. In the field of molecular biology the whole DNA extraction, amplification and detection process can be integrated on a chip. This not only simplifies the process for end-users, but also implies a significant cost reduction per preparation. Miniaturized setups even allow for the development of multiplexed assays (e.g. qPCR). Faster protocols are possible due to the shorter reaction steps and/or quicker separation times. This trend...

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