Product Catalog 2023 Magnetic Sample Preparation Solutions

Introduction magtivio BV was founded in 2018, as successor of MagnaMedics and is privatelyowned and financed. Production, quality control, logistics, R&D, sales and customer service are located in Nuth, The Netherlands. We are an independent producer of silica-enclosed iron-oxide nano-particles. Our magnetic beads are used as sample preparation solutions in research and diagnostic laboratories. Application areas are genomics (nucleic acid) purification, sequencing clean-up, immunoassays and proteomics investigations from human (swabs, saliva, plasma, serum, urine, tissue, cells, stool), animal...

Our core technology magtivio designs, develops, and manufactures superparamagnetic and ferrimagnetic silica-enclosed iron-oxide magnetic beads. Their main, desired properties... • Low magnetic remanence; the remaining magnetization of the beads themselves, after a magnetic field has been applied on them Ease of resuspension and low sedimentation rates Terminal functionalized groups can be connected to the silica coating of our beads. Modes of selection Our magnetic beads and complete kits, available under the brand names MagSi and MagSiMUS can be used for different selection modes • Positive...

MagSi-DNA Stool MagSi-DNA Beads

Viral RNA extraction for subsequent in-vitro diagnostic assays MagSi-DX Pathogen is intended to be used for the isolation and purification of viral RNA for subsequent in-vitro diagnostic purposes. The kit can be used with human respiratory swabs and saliva. The kit is designed to be used with any downstream application with amplification and detection of viral RNA (RT-qPCR, sequencing). The kit has been specifically validated for SARS-CoV-2 diagnostic workflows. Features  CE-IVD marked  Validated for SARS-CoV-2 diagnostics workflows  Short protocols, complete processing at room temperature...

MagSi-NA Pathogens Total nucleic acid extraction for pathogen detection (suited for Covid-19) The MagSi-NA Pathogens kit allows cost-effective extraction of DNA and RNA from a variety of sample materials like serum, plasma, oropharyngeal swab, nasopharyngeal swab, or any other respiratory samples. Purified total nucleic acids can be used for qPCR based or any other enzymatic pathogen detection method. The ready-to-use reagents and simple protocol are convenient in use and easy to automate. The included MagSi-PA7 magnetic beads are optimized for fast separation even from viscous sample lysates....

MagSi-NA Pathogens MSP Magnetic Sample Pooling: saving costs while maintaining sensitivity In case screening programs for e.g., Covid-19 are set up in low prevalence populations, sample screening becomes less cost-effective. A solution to overcome this issue is by pooling; adding multiple samples together in one well and analyse them as one, after which only the positive wells’ samples need to be reanalysed. While saving money on extractions and PCR reactions, classic sample pooling will result in a less sensitive assay with risk of false negative results. Our solution, Magnetic Sample Pooling...

MagSi-DNA Body Fluid Fast and cost-effective purification of genomic DNA from body fluids MagSi-DNA Body Fluid allows fast and cost-effective extraction of genomic DNA from blood, saliva, or swab samples. The magnetic bead-based kit can be used on fresh or frozen whole blood, buffy coat, fresh or preserved saliva samples or swab wash solutions. The ready-to-use reagents and simple protocol are convenient in use and easy to automate. As a linear volume to volume ratio is used between sample and reagents, it is possible to use the kit in any situation where high-quality genomic DNA is needed. Simple...

MagSi-DNA Tissue & Cells Purification of genomic DNA from mammalian tissue and eukaryotic cells The MagSi-DNA Tissue & Cells kit is intended for manual and automated purification of genomic DNA from mammalian tissue samples and eukaryotic cells. Processing time for the preparation of 96 samples is about 40 minutes plus an additional pre-lysis incubation of 15 min (for cells), 1-3 hours or overnight for tissue samples. The kit does not require phenol/chloroform extraction or alcohol precipitation and eliminates the need for repeated centrifugation, vacuum filtration, or column separation. It allows...

MagSi-cfDNA Purification of cell-free circulating DNA from liquid biopsy samples The MagSi-cfDNA kit is intended for purification of cell-free circulating DNA from serum and (frozen) plasma samples. Processing time for DNA purification of 24 samples is about 45 minutes. The kit requires no phenol/chloroform extraction or alcohol precipitation and eliminates the need for repeated centrifugation, vacuum filtration, or column separation. It allows safe handling of potentially infectious samples and is designed to avoid sample-to-sample cross-contaminations. The obtained DNA can be used directly...

MagSi-DNA Animal Purification of genomic DNA from Animal tissues and body fluids For aquaculture, fisheries and livestock management MagSi-DNA Animal allows fast and cost-effective purification of genomic DNA from various samples like blood, semen, hairs, saliva/swabs, or lysed tissue. This universal DNA purification kit is optimized to extract DNA from sample materials with the highest purity and delivers DNA which is suitable for genotyping assays or other PCR based analyses. The extraction chemistry has been validated on different species, e.g., horse, swine, dog, cattle (veterinary, livestock)...

MagSi-DNA Vegetal and MagSi-DNA Plant CLS kits allow for the purification of genomic DNA from various plant tissue types, like cotyl, seeds, leaves and roots, and from many different plant species. They have a very flexible setup, as the volume of each of the components can be adjusted to facilitate your specific requirements. The lysis buffers of our MagSi-DNA Vegetal and MagSi-DNA Plant CLS kits are specially designed for the effective breakdown of tough components in plant materials, allowing for the optimal release of the DNA to be isolated. The extraction itself is based on the binding of...