OMNISEC Unlock the power of advanced separations

Bioscience and biopharmaceuticals • Quantify key metrics in stability profiling and biosimilarity Multi-detection Size Exclusion Chromatography (SEC) or Gel Permeation Chromatography (GPC) is an essential analytical technique for the characterization of macromolecules. It provides deep insights into your sample’s absolute molecular weight, composition, size and structure. A series of three different detectors delivers critical information about your sample: Light scattering measures absolute molecular weight, independent of column retention volume or standards Differential viscometry measures...

OMNISEC multi-detector system A modern research environment demands a complete understanding of a sample’s molecular properties, including accurate and reliable measurements of molecular weight. Like other HPLC-based techniques, this involves the use of a pump, a column and at least one detector to measure the sample as it elutes. The ultimate in advanced detection is the combination of all these detectors to get a complete understanding of the molecule being investigated SEC is a well-established technique which separates the molecules in a sample according to their hydrodynamic volume as they...

OMNISEC software Powerful by design, yet easy and intuitive to use Workflow-focused software OMNISEC software has been designed with your priorities in mind to make GPC/SEC analysis easy and intuitive. The software guides you smoothly through setup, data acquisition and analysis in an intuitive workflow. Our complete and integrated gel permeation / size exclusion chromatography solution comprises: OMNISEC RESOLVE an integrated pump, degasser, autosampler and column oven for managing the separation within a single advanced unit OMNISEC REVEAL an integrated multi-detector module OMNISEC software...

OMNISEC REVEAL overview OMNISEC REVEAL detectors Integrated multi-detector module Detector modules Light scattering RALS Detector OMNISEC REVEAL is an integrated multi-detector module for advanced GPC/SEC measurements, incorporating refractive index, UV/Vis absorbance, light scattering and intrinsic viscosity detectors. The high sensitivity and measurement quality provided by OMNISEC REVEAL ensures maximum return on your investment. LALS Detector OMNISEC REVEAL can act as a standalone detector connected to your existing GPC/SEC system, or can work in combination with the OMNISEC RESOLVE module...

OMNISEC RESOLVE overview Degasser • Low volume degasser enables rapid solvent and buffer changeover OMNISEC RESOLVE is a combined pump, degasser, autosampler and column oven for mobile phase delivery and sample injection. • Improved degassing efficiency means more stable detector baselines What benefits does the complete OMNISEC GPC/SEC system provide? • One solution from a single manufacturer with an intuitive software package that handles everything from instrument control to data acquisition and data analysis • Unattended operation using the autosampler, even with sensitive samples such as...

SEC-MALS 20 detector Molecular size and absolute molecular weight The SEC -MALS 20 is a modular multiangle light scattering (MALS) detector for the OMNISEC system. It serves as a powerful additional detector which complements RALS/LALS or can be used as the sole light scattering detector. SEC-MALS 20 detector specifications SEC-MALS Detector system Parameter Laser type Laser power Analog signals accepted Data acquisition rate Molecular weight range <1000 up to more than 107 g/mol* Molecular weight accuracy Radius of gyration range Analysis models Zimm, Berry, Debye Detector range Linear range...

Product specifications at a glance OMNISEC REVEAL Parameter Dimensions (w, d, h) Parameters measured Recommended Windows ® 10 64bit OS, 4th generation i7 processor, 8GB computer specification physical memory and 1TB hard drive & DVD drive Data collection rate Dynamic range Baseline noise Molecular weight (Mn, Mw, Mz), dispersity (Mw/Mn), Hydrodynamic radius (viscosity), Radius of gyration, Intrinsic viscosity, Mark-Houwink a & K, Weight fraction, Concentration (per peak, total and composition), dn/dc, dA/dc, Sample composition, Titer, % full AAV, DAR Detector temperature control range Power requirements...

Service & Support When you make the invisible visible, the impossible is possible. Malvern Panalytical provides the global training, service and support you need to continuously drive your analytical processes at the highest level. We help you increase the return on your investment with us, and ensure that as your laboratory and analytical needs grow, we are there to support you. Our analytical systems and services help our customers to create a better world. Through chemical, physical and structural analysis of materials, they improve everything from the energies that power us and the materials...