Epsilon 1-4 LSCplus/Epsilon 2-4 LSCplus

Product catalog summary

Overview
The Epsilon 1-4 LSCplus and Epsilon 2-4 LSCplus are advanced benchtop freeze dryers designed for laboratory and pilot-scale lyophilization of solid or liquid products. These systems are suitable for use with ampoules, vials, glass flasks, plasma bottles, or dishes, offering high performance and quality.

Key Features

Temperature-controlled shelves for prefreezing and freeze drying.
Internal ice condenser temperatures of -55°C (Epsilon 1-4) and -85°C (Epsilon 2-4).
Compact chamber with shelf temperatures of -45°C or -70°C for sensitive products.
LSCplus Lyo-Screen-Control and LyoLogplus interface for process documentation.
Optional LPCplus software for PC-based process control, compliant with GAMP and cGMP guidelines.

Design and Technology

Vial stoppering and flask drying capabilities.
Liquid-cooled and heated shelves with a control range from -45°C to +60°C.
Efficient defrosting without water using radiation from shelf defrost ice condenser coils.
Intuitive LSCplus interface with a color touchscreen for process control.
Data storage and process documentation via USB or Ethernet.

Process Monitoring and Optimization

LyoLogplus software for process data collection and analysis.
LPCplus for online process data visualization.
Automatic determination of freezing point and product resistance using LyoRx sensor.
Comparative pressure measurement for end of main drying phase detection.
LyoBalance microbalance for direct measurement of weight loss during the process.

Technical Specifications

Epsilon 1-4 LSCplus: Ice condenser capacity of 4 kg, temperature range -45 to +60°C, nominal power 1.5 kW.
Epsilon 2-4 LSCplus: Ice condenser capacity of 4 kg, temperature range -70 to +60°C, nominal power 2.0 kW.
Both models feature CFC-free refrigeration and a noise level of 54 dB(A).

Customization and Compliance

Custom configurations available for clean-room integration, isolator/glove-box integration, and more.
Systems comply with cGMP/GLP guidelines and offer validation packages for GMP/FDA compliance.

Conclusion
The Epsilon 1-4 LSCplus and Epsilon 2-4 LSCplus freeze dryers provide robust solutions for lyophilization processes in pharmaceutical and biotech applications, offering advanced technology, comprehensive process control, and customization options to meet diverse needs.

Catalog excerpts

Epsilon 1-4 LSCplus/Epsilon 2-4 LSCplus-1

Epsilon 1-4 LSCplus Epsilon 2-4 LSCplus Pilot Freeze Dryers

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Epsilon 1-4 LSCplus/Epsilon 2-4 LSCplus-2

Advanced System Technology for Best Drying Results The benchtop freeze dryers Epsilon 1-4 LSCplus and Epsilon 2-4 LSCplus are high performance, universal laboratory and pilot systems for lyophilisation of solid or liquid products in ampoules, vials, glass flasks, plasma bottles or dishes. Epsilon 1-4 LSCplus and Epsilon 2-4 LSCplus set the standard for pilot systems of the highest quality and performance. They share a geometrical likeness with large production machines and use similar temperature-controlling systems. All operations are possible inside the unit: • Prefreezing of products on temperature-controlled...

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Epsilon 1-4 LSCplus/Epsilon 2-4 LSCplus-3

Process Optimisation in Detail LSCplus – colour touchscreen and intuitive operation To aid in designing your process run we have integrated our highly regarded production optimised interface – the LSCplus control system into every model. All of our accessories are plug and play and the integrated automatic process sequences ensure reproducible results. Process monitoring We understand process monitoring and documentation is crucial to the validation of many applications regardless of the run and the run size. Epsilon 1-4 LSCplus and Epsilon 2-4 LSCplus offer a variety of options to optimise your...

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Epsilon 1-4 LSCplus/Epsilon 2-4 LSCplus-4

Comprehensive Range of Customized Solutions Technical Specification With the Epsilon 1-4 LSCplus and Epsilon 2-4 LSCplus Martin Christ has set a standard for high-quality and flexible entry pilot-models. Units provide the highest level of functions for successful research and process development. Systems with customized configurations have been supplied to global acting pharmaceutical companies and Biotech start-ups. Modifications include: • Clean-Room Integration • Isolator / Glove-Box integration • Automatic vial stoppering • H2O2-decontamination • Special systems for solvents, including GN2-inerstisation...

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Epsilon 1-4 LSCplus/Epsilon 2-4 LSCplus-5

Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode • Germany Tel. +49 (0) 55 22 50 07-0 Fax +49 (0) 55 22 50 07-12 [email protected] www.martinchrist.de

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