Best Freeze Drying Solutions The ultimate plus Pilot Freeze Dryers Epsilon 2-6D LSCplus Epsilon 2-10D LSCplus

Best Drying Results

Advanced System Technology for Best Drying Results The freeze dryer EPSILON 2-6D/2-10D LSCplus is a high performance universal laboratory and pilot unit for freeze drying of solid or liquid products in ampoules, vials, glass flasks, plasma bottles or dishes. All operations are possible inside the unit: • Pre-freezing of products on liquid-controlled shelves down to a shelf temperature of approx. –50°C to +60°C according to preselected desired time and temperature limits • Freeze drying (sublimation) of products according to preselected desired time, temperature and pressure limits. Shelf temperature...

Design Features • Vial stoppering Easy and safe • Powerful shelf temperature control Liquid cooled and heated shelves, control range -50 to +60 °C (freezing and main drying), shelf temperature accuracy +/-1K. Defrosting without water Via reverse operation of compressor system the ice condenser coils can be defrosted very efficient („hot gas defrosting“). No production of additional waste. Optimal vapour transport 120 mm diameter valve, ice condenser directly behind drying chamber (no pipe connection which results in a pressure drop). Uncompromising Process Control Via intuitive, simple to control...

Most Comprehensive Range of Customized Solutions With the Epsilon-Pilot-Range Martin Christ have set the standard for high quality and productive pilot systems. These freeze dryers look and function in a very similar way to the large production freeze dryers. They provide the highest level of functions for successful research and process development. Pilot systems with customized configurations have been supplied to global acting pharmaceutical companies and Biotech start-ups. Modifications include: • Clean Room Integration • Isolator / Glove Box Integration • Process Optimization Tools (PAT...

[LSCplus - colour touchscreen and intuitive operation To aid in designing your process run we have integrated our highly regarded production optimised interface-the LSCplus control system into every model. All of the accessories are also integrated. Automatic process sequences ensure reproducible • Picture driven touchscreen control • Automatic or manual sequence of freezedrying processes • Intuitive input of programs based on different freezedrying • Graphical diagram of the freezedrying process • Selection of different switching conditions, depending • Storage memory for up to 32 user-defined...

Process monitoring and documentation We understand process monitoring and documentation is crucial to the validation of many applications regardless of the run and the run size. Therefore process data collected during a run on our system can be documented and archived with the aid of the LyoLogplus software available for installation on an external PC. Complete run data and settings can be transferred from the freeze dryer via USB or Ethernet. LyoLogplus enables the subsequent analysis of the processes by way of an intuitive user interface. For further versatility it is also possible to use LPCplus...

Process optimisation With the aid of pre-defined FD-programs/recipes and intelligent interactions of product relevant parameters such as • Product temperature • LyoRx (electrical resistance) • Pressure data (pressure increase test, comparison between Pirani- and capacitive sensor) and in combination with the FD-control System LSCplus, a self-optimizing cycle mode can be defined. As a result, time and costs for cycle development and transfer to production can be reduced by at least factor 3 compared to conventional freeze dryers. WTMplus in Pilot units Optional is a wireless temperature measurement...

Process optimisation in detail The LSCplus series offers a variety of options to optimise your freeze drying processes. In addition to documentation and key parameter analysis, the automatic determination of critical product data is also available. Our intelligent systems even offer the option of automatic tuning for set values based on current process conditions. As a result, these laboratory freeze dryers offer numerous options for supporting process development and optimisation, which can provide important findings designed to enable confidence in scale-up conditions. Freezing point Our LyoRx...

Technical Specification Epsilon 2-6D Shelf system – dimensions (W x D) – temperature range – temperature accuracy Number of shelves and capacities see table on next page Refigeration system Power supply (other voltages on request) Nominal power of the basic unit Communication interface Defrosting function Vial stoppering – manual – hydraulic – automatic function ”aeration-stoppering-storage“ LyoControl (freezing point determination, measurement of product ressistance) End point determination – product temperature measurement – WTMplus ”Wireless Temperature Measurement“ – pressure increase test...

Shelf temperature: Shelf temperature accuracy: max. ±1 °C on shelf and from shelf to shelf Drying chamber dimensions: Shelf dimensions: Overall dimensions: Shelf Capacities Shelf Capacities (vials) Shelf width : Shelf length: Technical Specification: Qty of shelves Area Spacing Air-cooled system with 21independent0,07 refrigerator systems + 1 250 280 (optional water-cooled system available): 2 Numbers are max loading, subtract 10 % when using frames! Ice condenser: 280 Ice condenser performance: Qty of shelves Area Spacing Ice condenser temperature: Tray only Tray only Shelf temperature accuracy:...

Freeze Dryers Rotational Vacuum Concentrators Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Sose 50 • D-37520 Osterode am Harz www.martinchrist.de • [email protected]