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Laboratory Freeze Dryers Advanced Applications

Laboratory Freeze Dryers Advanced Applications
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Laboratory Freeze Dryers Advanced Applications

Product catalog summary
Overview: The document provides a comprehensive overview of the LSCplus series of laboratory freeze dryers by Martin Christ, emphasizing their advanced applications, intuitive control systems, and wireless technology. It also includes detailed technical specifications and configurations for freeze drying systems and vacuum concentrators.
Specifications: The LSCplus series offers freeze dryers with ice condenser temperatures of -55°C and -85°C, and capacities ranging from 4 kg to 24 kg. These systems are suitable for aqueous products and those with solvents or low freezing points. Specifications for models such as Alpha, Beta, Gamma, and Delta series include ice condenser capacity, performance, temperature, chamber volume, shelf temperature, refrigeration system, dimensions, weight, power supply, communication interface, refrigerant type, noise level, and defrosting function.
Control System: The LSCplus control unit features a color touchscreen for intuitive operation, supporting both manual and automatic processes. It integrates various PAT tools for enhanced process management and control, ensuring compliance with GMP/GAMP standards.
Wireless Shelf Technology (WST): This innovative technology eliminates the need for cables, allowing for easy shelf handling and improved process control. Each shelf is equipped with a removable LyoBus module, facilitating uniform drying and precise temperature regulation.
Drying Methods: The systems support single-chamber and double-chamber methods, catering to different product requirements. The single-chamber method is suitable for low freezing point substances, while the double-chamber method allows for pre-freezing and a variety of accessories.
Process Monitoring and Documentation: The LyoLogplus and LPCplus software enable comprehensive process documentation and monitoring. These tools support data acquisition, real-time process control, and seamless documentation, adhering to cGMP and GLP guidelines.
Process Optimization: The LSCplus series offers features for process optimization, including freezing point determination, product resistance monitoring, and pressure increase tests. These capabilities support process development and scale-up analyses.
Example Configurations: Detailed configurations for different models (Alpha, Beta, Gamma) are provided, highlighting their suitability for various applications. Example configurations for Delta 1-24 LSCplus and Delta 2-24 LSCplus include the number of vessels, shelf spacing, and special features like heated shelves and stoppering devices.
Technical Features: The document emphasizes features such as vacuum measurement and control, temperature measurement for ice condensers and shelves, end-point determination through product temperature measurement, pressure increase tests, and capacitive pressure measurement. Optional software for process documentation and control is also mentioned.
Product Range: Martin Christ offers a wide range of freeze drying systems for industrial production, pilot systems for process development, and systems for routine applications or R&D. Rotational vacuum concentrators are available for various applications, including high-end pharmaceutical research.
Contact Information: The document concludes with contact details for Martin Christ Gefriertrocknungsanlagen GmbH, including their address, phone number, fax, email, and website.
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Catalog excerpts

Laboratory Freeze Dryers Advanced Applications-1

Laboratory Freeze Dryers Advanced Applications LSCplus: intuitive and wireless

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Optimal process control and reproducibility for fastest possible and reliable freeze drying We are the leading manufacturer of freeze drying systems, with over 65 years of experience in all aspects of freeze drying, including devices for special applications. We offer you a closely graduated series of systems for product-specific freeze drying with a wide range of optimisation options. The highly diverse, modularly structured range of accessories allows the laboratory freeze drying systems to be used for a wide variety of tasks. Outstanding products thanks to superior technology and comprehensive...

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Selection criteria Graduated ice condenser temperatures and drying capacities The laboratory freeze dryers in the LSCplus series are available in several sizes with a wide range of accessories to match individual applications. Alpha 1-4 LSCplus Alpha 2-4 LSCplus Product designation format 4 kg Product series Controller type Ice capacity One-stage refrigeration system Laboratory freeze dryer systems are also available with two different ice condenser temperatures: Temperature Typical application area –55 °C (one-stage refrigeration system) Aqueous products –85 °C (two-stage refrigeration system)...

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Beta 1-8 LSCplus Beta 2-8 LSCplus 8 kg Delta 1-24 LSCplus Delta 2-24 LSCplus 24 kg

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Convenience and time savings thanks to wireless technology.

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Wireless Shelf Technology (WST) Unique wireless technology with easy shelf handling Unique and innovative (patent pending) Wireless Shelf Technology (WST) eliminates the need for cables between the freeze drying system and the heated shelves. Each shelf is equipped with an easily removable LyoBus module. This system also gives you significantly better process control and process monitoring options. • Heated shelves without a separate controller, for a fast and regulated drying process • Uniform drying thanks to a temperature distribution of ±1 K over the shelves with individual energy input for...

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Drying Methods for Laboratory Systems The new freeze drying systems with the LSCplus controller set standards for application diversity and process control. The modular range of accessories enables application-specific configurations that fulfil all requirements. Two different drying methods are available to handle virtually every task. Single-chamber method (inside) With this unique configuration, the product is frozen inside the ice condenser chamber and then dried. This method is particularly suitable for substances with a low freezing point or thermally unstable substances. In this method,...

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LSCplus System Controller Colour touchscreen and intuitive operation The LSCplus system controller incorporates pioneering technologies to provide a simple, intuitive user interface. All of the accessories are also integrated. Reproducible results are assured by automatic process sequences. • Colour touchscreen with clear presentation • Automatic or manual sequencing of freeze drying processes • Intuitive program entry using various freeze drying sequences or recipes • Memory for 32 user-defined programs • Graphical display of freeze drying sequence • Choice of several continuation conditions...

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Process Monitoring and Documentation Laboratories in particular are increasingly subject to stringent requirements such as validation or process monitoring. Documentation and archiving of all process data is possible with the LyoLogplus software, which can be installed on a separate PC. The data can be transferred from the freeze drying system to the PC on a USB stick or directly over Ethernet. LyoLogplus enables seamless documentation and post-process analysis with an intuitive user interface. LPCplus can also be used. With LPCplus you can develop programs for freeze drying and view process...

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Process Optimisation The freeze drying systems in the LSCplus series provide various options for the optimisation of freeze drying processes. Along with the documentation and analysis of many types of essential data, critical product data can be acquired and used for monitoring and process control in fully automatic programs. In this way, theses laboratory freeze drying systems offer many features to support process development and optimisation, which can provide important information for scale-up analyses. Comparative pressure measurement The end of the main drying phase can also be deduced...

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20 Drying manifold for round-bottom flasks, wide-neck filter bottles or ampoule distributors; specifically suitable for drying with solvents. a) For round-bottom flasks, wide-neck filter bottles or ampoule distributors b) Distance for stoppering device Alternative configurations available upon request.

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Drying manifold for round-bottom flasks, wide-neck filter bottles or ampoule distributors; specifically suitable for drying with solvents. Alternative configurations available upon request.

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Example configurations Gamma 1-16 LSCplus Gamma 2-16 LSCplus Special features Freezing and drying inside the ice condenser (one-chamber method) on heated shelves, spacing variable by removing individual shelves, optionally with a fan. Freezing and drying inside the ice condenser (one-chamber method) on heated shelves with stoppering device, spacing can be increased to 110 mm by removing a shelf, optionally with a fan. For round-bottom flasks, wide-neck filter bottles or ampoule distributors; specifically suitable for aqueous products. For round-bottom flasks, wide-neck filter bottles or ampoule...

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Freezing and drying inside the ice condenser (one-cham-10 200 mm 0.31 m2 25 mm ber method) on heated shelves, spacing variable by removing individual shelves, optionally with a fan. Freezing and drying inside the ice condenser (one-cham-45 b ber method) on heated shelves with stoppering device, mm spacing can be increased to 110 mm by removing a shelf, optionally with a fan. For round-bottom flasks, wide-neck filter bottles or ampoule distributors; specifically suitable for aqueous products. Heatable shelves, variable spacing by removing individual shelves, additional optional connectors...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.