Taking Noninvasive Monitoring to New Sites and Applications ™

A Letter from the Chairman & CEO DELIVERING ON OUR MISSION AND GUIDING PRINCIPLES Over 23 years ago, Masimo started with a bold mission to improve patient outcomes and reduce the cost of care by taking noninvasive monitoring to new sites and applications. We also set forth guiding principles that stay with us today: > emain faithful to your promises and responsibilities R > Thrive on fascination and accomplishment and not on greed and power > Strive to make each year better than the year before both personally and for the team > Make each day as fun as possible > Do what is best for patient care...

infringement lawsuit against Nellcor, we received enough of early investors. While this would have resulted in great personal gain to some insiders, we instead let stockholders keep their preferred shares and fully benefit from a large dividend while we geared up to take our company public. When other companies refused to provide their pulse oximeters for use in home care because of the potential liabilities vis-à-vis high-risk patients, we decided to make our patients on the general floor. Approximately 10 years after products available because we knew they provided the best the introduction...

The Masimo product offering Monitors masimo patient Safetynet™* A complete line of bedside and handheld monitors for clinicians in acute and alternate care settings. Wireless remote monitoring and clinician notification system designed to keep patients safe on general care floors. * The use of the trademarks PATIENT SAFETYNET and PSN is under license from University Health System Consortium Circuit Boards The leading pulse oximetry solution, available in more than 100 OEM monitors from 50 leading brands. Our rainbow measurements have also allowed us to increasingly extend Masimo’s reach beyond...

® Signal Extraction Technology: Solving the “Unsolvable” Twenty-three years ago, two young engineers asked themselves why pulse oximetry wouldn’t work during patient motion and low perfusion – and by doing so, set a new course that created a revolution in patient monitoring. OVERCOMING THE LIMITATIONS OF CONVENTIONAL PULSE OXIMETRY Performance During Motion and Low Perfusion1 Since its inception, pulse oximetry was plagued by unreliability when it was needed most – during patient motion and low perfusion. The industry had given up and considered the problem “unsolvable” Clinicians . FALSE ALARM...

True & False SpO2 Alarm RateS of Masimo SET vs. 19 Competing Pulse Oximetry Technologies1 Industry-leading Pulse Oximetry Solution 100 90 Philips 24C Philips CMS-B Datex-Ohmeda 3740 Nellcor N-395 Datex-Ohmeda AS-3 Datex-Ohmeda 3800 Datex-Ohmeda 3900 Nellcor N-200 Philips CMS Nellcor N-295 GE 8000 Novametrix MARS Nellcor NPB-190 Nellcor NPB-180 Novametrix 520A Spacelabs 90308 Nonin 8600 BCI 3304 Criticare 5040 70 Sensitivity (%) Masimo SET is the world’s leading pulse oximetry technology, proven by both independent and objective research and the real-world success of our customers and partners....

Freeing Hospitals to Choose the Best Technology for Patient Care Masimo has also helped change and improve healthcare by being a champion for free choice in the market and the protection of new technology development. Group Purchasing Reform Masimo has fought hard to prevent this type of behavior, A short decade ago, many hospitals wanted to choose testifying twice at Senate hearings regarding these practices Masimo SET pulse oximetry to provide the best care for their and bringing a successful antitrust suit against Nellcor, a patients, but could not do so because their group purchasing division...

Supporting Clinicians in Reducing Blood Transfusions and Detecting Bleeding Earlier with SpHb ® With the rainbow® measurement platform including noninvasive total hemoglobin (SpHb), Masimo technologies aid some of the most common, costly, and critical decisions made in healthcare. Reducing UNNECESSARY BLOOD TRANSFUSIONS While blood transfusions are critical to avoid organ damage and sustain life when hemoglobin levels are unstable or very low, mounting evidence shows that transfusions increase 30-day mortality by up to 38% and 30-day morbidity by up to 40%.1, 2, 3 Blood transfusions are also...

Aiding Clinician Assessment of Fluid Responsiveness and Fluid Management Fluid administration is one of the most common hospital interventions. Although it is critical to improving patient status and enabling end organ preservation, unnecessary fluid administration is associated with increased morbidity and mortality.1 Fluid Non-Responders Detection This observational study evaluated 25 surgical patients before and after volume expansion, with fluid responders (sensitivity) defined as a cardiac index increase of>15% and fluid non-responders (specificity) defined as a cardiac index increase of...

Helping Improve Outcomes on the General Floor with Masimo Patient SafetyNet™ As part of our mission to take noninvasive monitoring to new sites and applications, Masimo SET has enabled accurate and reliable monitoring in care areas where conventional pulse oximetry has faltered, such as the general floor of hospitals. REDUCING RESCUES AND ICU TRANSFERS Clinical Impact of Masimo SafetyNet1 For many years, clinicians have understood the risks of not continuously monitoring patients on the general 65% 135 48% floor. However, excessive false alarms due to patient motion made improving the safety...

Integrating Measurements to Enable Meaningful Use Clinician-centric Monitoring Today’s challenging hospital environment exposes clinicians to increasing amounts of information with expanding documentation requirements. Masimo innovation simplifies and automates this process, streamlining workflow and improving patient safety by empowering clinicians to focus on patients rather than technology. My View™ empowers clinicians to see what they want, when they want to see it. The level of needed information can change dramatically by clinician and care area, but medical devices historically function...