Cardiologic
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The CARDIOLOGIC is a complex cardiovascular system that provides unique automated evaluation services for investigations and analysis of standard 12-lead ECG signals and blood pressure values.

(1^ Wearable medical grade ECG with 3 - 12 lead ECG cables (2) Wearable medical grade Non-Invasive Blood pressure meter (3^ Tablet controlled wireless software solution - convenient usage (4) Combined wireless pressure sensor for the Valsalva maneuver and Handgrip tests @ Sterilized disposable mouthpieces for the Valsalva maneuver Automated Cardiac Neuropathy screening function with all 5 cardiovascular reflex test and automatic score value determination. At the end of the test the system provides a comprehensive report with the major cardiac parameters. Examination of the parasympathetic...

Built in comparison mode where the records could be compared to a previous or to standard curve. Resting ECG mode with automated and comprehensive report functions about all frequently used cardiac parameters • Easy to use HRV analysis module Sophisticated analysis of myocardial ventricular repolarization by providing Qt determination (QT interval), (QT dispersion) and temporal variability, (QT variability), QTc QT values are corrected by Bazett formula Classic 4 – 12 lead automated ECG evaluation WITH THE FOLLOWING PARAMTERS RR Distance, HR Heart rate, ST Distance, QT Distance, QRS Length...

An estimated 60% of people with diabetes have some form of nerve damage or neuropathy. Cardiac Autonomic Neuropathy occurs in 22% of Type 2 diabetics, and in 17% of Type 1 diabetics1. 25–50% of diabetic patients with symptomatic autonomic neuropathy die within 5-10 years. Cardiac Autonomic Neuropathy in diabetes has been called a “silent killer”, because so few patients realize that they suffer from it and yet its effect can be lethal. Early detection of Cardiac Autonomic Neuropathy and intervention are of prime importance in preventing early dea

Orthostatic Hypotension Heart Failure Sexual Dysfunction Cardiologic enables you to comply with the American Diabetic Association’s recommendation for detecting Cardiac Autonomic Dysfunction by evaluating precise R-R changes with simple physiological excercises. These critical cardiovascular reflex tests can be performed by an assistant – without the presence of a doctor - using the 4-step automatized reflex step functions

METHODICAL BACKGROUND Cardiovascular autonomic neuropathy (CAN) often occurs in patients with diabetes, in liver disease, in autoimmune disease by regular alcohol consumers, and in people suffering from metabolic syndrome. Complications caused by CAN threatens the quality of life and life expectancy of the patients. CAN is the most examined form of autonomic nervous system dysfunctions, which can be detected by the easy-to-use and reproducible testing methods. The involvement of the autonomic nervous system may also affect cardiac electrical activity, including ventricular repolarization....

One of the earliest indicators of cardiovascular neuropathy is a reduction in heart rate variability (HRV), which is also an independent predictor of sudden cardiac death in many conditions. Parasympathetic and sympathetic dysregulation of the cardiovascular system can lead to the development of a number of other well-defined symptom complexes that can profoundly affect life expectancy. Impairment of autonomic innervation may be manifested by deterioration of the reflexes responsible for cardiovascular adaptation, which may lead to marked abnormalities in the complex system of blood...

The characterization of autonomic nervous system function is most easily performed with the well reproducible and well standardized cardiovascular reflex tests (CRT) described by Ewing. The test is based on the analysis of ECG signals and blood pressure values recorded continuously during the reflex tests. One set of reflex tests (orthostatic blood pressure drop, handgrip test) predominantly characterizes sympathetic nervous system function, while the other set (deep inhalation and exhalation on heart rate response, Valsalva maneuver, 30/15 ratio) characterizes parasympathetic nervous...

3. 30/15 ratio - change in heart rate in response to active orthostasis: under physiological conditions, the heart rate increases temporarily after standing up and then decreases. Tachycardia reaches its maximum around the 15th beat after standing, and bradycardia reaches its minimum around the 30th beat after standing. Test: the patient stands up in 5 seconds after 3 minutes of lying still and remains standing for 1 minute. On a continuous ECG recording, the RR interval of the 30th or so beats after standing and the RR interval of the 15th or so beats are expressed as the ratio of the RR...

Based on the results of each reflex test, a “score” (normal: 0, borderline: 1, abnormal: 2) was calculated, from which, using the scores of the 5 cardiovascular reflex tests (CRTs), an aggregated autonomic score ranging from 0 to 10 was calculated to express the severity of the neuropathy.

The Cardiologic software provides a simple quick solution for deriving and scoring neuropathic tests: By automatically displaying the appropriate text instruction in a timely manner. By continuously recording and marking the data (ECG curve, blood pressure values). By Rapid evaluation of the recorded data and calculation of autonomic neuropathic score values. Assessment of the autonomic nervous system functions can be done most easily by the reproducible and properly standardized cardiovascular reflex tests (CRTs) described by Ewing. The examination is based on analysis of the ECG and blood...

Before we start the detailed review, we would like to quote a now classic quote from Professor Arthur Vinik: “Know autonomic neuropathy and you will know the whole of Medicine.” This idea describes well that the different manifestations of AN (Autonomic Neuropathy) can affect the whole body and that the circulatory system is particularly affected. In the following I will illustrate with a few typical examples the importance of the cardiovascular risk factor and, consequently, demonstrate the current development of a diagnostic interface for this factor (for which this measurement system is...