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Isolated nerve tissue system

Isolated nerve tissue system

Isolated nerve tissue system

Product catalog summary
Overview: The NEU-01 Four Channel In-Vitro Superfusion System is designed for studying neurotransmitter release through electrical or chemical stimulation of nerve tissues. It is a mobile and user-friendly system that facilitates the collection of neurotransmitters.
Main Components:
  • Central Unit: Includes a superfusion chamber and pre-heater. It consists of an incubation chamber with a carbogen controller, slice chambers with bubble traps, and stimulating electrodes.
  • Thermal Stabilizer and Buffer Conveyor Unit: Maintains the temperature and delivers buffer liquid to the measuring space.
System Features:
  • The incubation chamber keeps tissue slices alive and at the correct temperature using a carbogenized environment.
  • Slice chambers are designed for quick and safe insertion of tissue slices, ensuring efficient stimulation and stable temperature conditions.
  • The system supports continuous, bubble-free flow of buffer liquid, with temperature control between 25-45°C.
Functionality: The system aids in studying neurotransmitter release by providing a stable supply of oxygen and nutrients to nerve tissues. It uses a closed-system superfusion device with a peristaltic pump for continuous supply of pre-heated, carbonized physiological solution.
Advantages:
  • Allows for simultaneous study of different neurotransmitter releases using isotopes like tritium and 14C.
  • Provides quick test results within hours due to the radioactive neurotransmitter release technique.
  • Suitable for both electrical and chemical stimulation-induced release of neurotransmitters.
Innovations: The LU-01 Loading Unit offers a reliable, faster, and safer method for isotope delivery to tissues, integrating seamlessly into the measuring system.
Contact Information: MDE GmbH, Schwanthaler Str. 5, 80336 München, Germany; Podmaniczky Street 87, 1064 Budapest, Hungary. Email: [email protected]
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Catalog excerpts

Isolated nerve tissue system-1

Isolated nerve tissue system

 Open the catalog to page 1
Isolated nerve tissue system-2

Isolated nerv tissue system The solutions of the in-vitro superfusion release technique result in a system, which is easy to use and can be assembled in a mobile way. It makes possible to get the neurotransmitters with electrical or chemical stimulation from the nerve tissues (for details see How can the system help? section). The system consists of three main units: 1. The central unit with superfusion chamber and pre-heater, 2. Heat-stabilizer and buffer conveyor unit. | Water-jacket Buffer Carbogen

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Isolated nerve tissue system-3

Isolated nerv tissue system COMPONENTS: 1. Central unit with superfusion chamber and preheater. The component elements are placed on a specially designed stand in the following order, going from the top to the bottom: a) Incubation chamber with carbogen controller, b) Slice chambers with bubble trap and stimulating electrodes (superfusion unit), c) Thermal equalizer pigs (pre-heater). A) INCUBATION CHAMBER WITH CARBOGEN CONTROLLER The double-walled, 10 ml capacity chamber is connected to the thermo stabilizing unit through the liquid steamed in the outer sheath. The chamber is to keep the tissue...

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Isolated nerve tissue system-4

Isolated nerv tissue system The slice chamber is the most important element of the system. So it was designed in a way, which makes it possible for the tissue slice to be put into the chamber the fastest and safest way possible, before t he measurement. It is also important that the stimuli, starting the process (electrical or chemical stimulation), can reach the tissue slice with the best efficiency. Besides keeping the buffer liquid in a stable temperature, the continuous and bubble-free flow must also be supported. To ensure these conditions, the chamber is made up from five easily attachable...

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Isolated nerve tissue system-5

Isolated nerv tissue system EXP-ST-04 Square wave stimulator HOW CAN THE SYSTEM HELP? The study of neurotransmitter release and influencing the carbogen (95% O2, 5% CO2) gas meter and the perfusion experiment are essential parts of studying information chambers. The great advantage of the perfusion chamber transfer between nerve cells and other regulatory process- is that it is suitable for the examination of electrical field es. Neurotransmitter release in in-vitro circumstances can stimulation-, and chemical stimulation-induced release of be performed by the electrical or chemical stimulation...

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Isolated nerve tissue system-6

Isolated nerv tissue system In contrast to the conventional type isotope delivery to tissue (soaking), we developed a more reliable, faster and safer method. For this we have developed the LU -01 LOADING UNIT, which can be organically integrated into the measuring system. The essence of the LU-01 loading unit is that the tracers (e.g.: isotope) can be introduced in to the tissue from a closed, heat-stabilized liquid chamber by nerve impulses. The tissue is placed in the incubator vessel the same way as it is placed in the perfusion unit of the measuring system. The same applies to the transmission...

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Isolated nerve tissue system-7

[email protected] www.mdegmbh.eu MDE GmbH- Schwanthaler str. 5. 80336 Munchen, Germany Podmaniczky Street 87, 1064 Budapest, Hungary

 Open the catalog to page 7
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.