MEASURE THE ANS CONTROL SURGICAL STRESS IMPROVE OUTCOMES ANI V1 Monitor The Analgesia Nociception Index The Analgesia Nociception Index (ANI) technology is a novel, innovative technology providing a measure of the parasympathetic tone to continuously evaluate patient comfort level. ANI allows physicians to titrate analgesics to control nociception. ANI offers the ability to: Titrate opioids avoiding infra and overdosing Daccache G et al., Anaesthesia Critical Care & Pain Medicine, 2016. Diagnose the etiology of the hemodynamic event Logier R et al., IEEE, 2011. Predict post-extubation pain Boselli E et al., British Journal of Anaesthesiology, 2013. Reduce post-operative pain Henry D. Upton, et al Anesthesia & Analgesia July 2017. Predict hemodynamic reactivity Jeanne M et al., Clin J Pain, 2014. Reduce length of stay Ramos et al J Clin Monit Comput. 2020 Feb 28. Maintain hemodynamic stability Daccache et al., Anaesthesia Critical Care & Pain Medicine, 2016.

ANI Monitor V1 Specifications Parameter Power Requirements 100-240 VAC through AC power adapter Main Frequency AC Power consumption Battery Type Battery Charge / Discharge About 6 hours / 1 hour 30 minutes Patient Leakage Current Environmental Parameter Cooling Method Temperature Operating Storage Humidity Operating Storage Altitude Operating Storage Dimensions Monitor Acquisition Device Weight Monitor Acquisition Device Finish Monitor Acquisition Device Front : white and orange Back : white ANI Monitor V1 is a class IIa medical device, manufactured by MDoloris Medical Systems, CE evaluation...