AFERsmart is a multitherapic platform able to perform a variety of treatments to treat numerous diseases. AFERsmart performs the following treatments : • Therapeutic Plasma exchange • Rheopheresys - Double filtration - Selective apheresys - Double filtration adsorption • Hemoperfusion Complete treatments directly on the blood or by treating the plasma coming from a centrifuge. AFERsmart is a compact and complete, easy to use equipment: • Only two pumps allow to move blood or plasma • Two double clamp handle rapid cycles of regeneration of the fractionator filter fully automatically • The management of the extraction of plasma is entrusted to a single clamp • In plasmapheresis the control of the entire treatment is made according to the TMP pressure that monitors and automatically optimizes all flows making the treatment easy and secure. The simple and intuitive interface is based on a colour display complemented by a thumbwheel and only

Available Treatments Rheopheresis DOUBLE FILTRATION PLASMA EXCHANGE Rheopheresis SELECTIVE APHERESIS Rheopheresis DOUBLE FILTRATION ADSORPTION ELECTRICAL DATA TECHNICAL DATA Power supply Blood flow Ranging from 5 to 250 ml / min - Resolution 5 ml / min (DF DFA - SA - TPE - HP) Ranging from 1 to 30% of QB - Resolution 1 ml / min (DF - DFA - SA) Power adsorption Plasma flow 52 VA under normal conditions 110 VA for a second reopening elettropinza Ultrafiltration flow Variable from 0 to 20% of QB - Resolution 1 ml / min (TPE) Infusion flow Variable from 0 to Quf - Resolution 1 ml / min (TPE) Priming...