multi-LOC 6F conférence Dr. Amendt

Product catalog summary

Introduction
Dr. K. Amendt from the Center of Vascular Medicine in Speyer, Germany, presents a technical document focusing on vascular surgery, particularly addressing the challenges and advancements in treating long lesions in femoral-popliteal (fem-pop) arteries.

Potential Conflicts of Interest
Dr. Amendt discloses potential conflicts of interest, having served as an advisory board member and consultant for companies such as BAYER AG, Boehringer Ingelheim, and UCB Pharma.

Historical Context and Current Challenges
The document references historical figures in vascular surgery, Alexis Carrel and Rene Lerich, and discusses the evolution of surgical techniques. It highlights the need for less invasive procedures that surpass traditional open vascular surgery in effectiveness.

Primary Patency in Long Lesions
The document emphasizes the challenges in maintaining primary patency in long lesions (>40-50mm) in fem-pop arteries. Key issues include disease progression, recoil, flap, dissection, early intimal hyperplasia, and ongoing vessel wall trauma. Late remodeling and long-lasting trauma are also noted as significant concerns.

Technological Advancements
Various technologies and methods are discussed, including stents, covered stents, Viabahn, drug-eluting balloons (DEB), and drug-eluting stents (DES). The document stresses the importance of medication and training alongside these technologies.

Studies and Tools (2007-2013)
Several studies conducted between 2007 and 2013 are mentioned, focusing on different tools and stents, including LUMINEXX, SMART, Protege, LifeStent, Astron 18, Absolute, Zilver, Supera, and Viabahn. The studies explore the effectiveness of nitinol stents, both with and without drugs, in randomized settings.

Innovative Approaches
The document introduces the Multi-Loc and Multi-Stent-Delivery-System, which allows for custom-length stent implantation, demonstrated in domestic pig models.

Conclusion
The document concludes with a call for continued innovation and improvement in vascular surgery techniques to achieve superior outcomes compared to traditional methods.

Catalog excerpts

The concept offocal stenting-Lessons learned and future perspectives ^Di«koniekr<nkcnhiu> Center of Vascular Medicine „Oberrhein“ (Mannheim - Speyer) Clinic for Internal Medicine I: Angiology, Cardiology and Subsequent Complications of Diabetes mellitus Diakonissenkrankenhaus Mannheim Germany Academic Teaching Hospital Clinical Medicine Mannheim University Heidelberg [email protected]

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6.-%,&-42#$ I have the following potential conflicts of interest to report: Advisory Board and Consultant: BAYER AG Boehringer Ingelheim UCB Pharma

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The concept offocal stenting-Lessons learned and future perspectives NCBI Resources 0 How To 0 US NaDonai Library of Meflicine National l«sttutes of Health Show additional filters Display Settings: 0 Summary, Sorted by Recently Added Article types Review More ... See sfa cold shock gene in the Gene database sfa in Escherichia coli CFTQ73 | Escherichia coli Q157:H7 sir. EDL933 | Escherichia coli UTI891 All 52 Gene records Text availability Abstract available Full text available Publication dates 10 years Custom range. □ Contemporary endovascular treatment for disease of the superficial femoral...

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Lesion length Spectrum of arteries It is good to be less invasive - but not enough: we must become superior to open vascular surgery Patency @ 5a: 80% AK Patency @ 5a: ?? Fem.-pop: Balloon < 45% Stent: ?? Open vascular surgery

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F+'+/#9#')$&*$(2&=,#9-$ Primary Patency In long lesions (> 40-50mm) fem.-pop medication training Progress of disease Recoil Flap Dissektion Early Intimal hyperplasia Ongoing vessel wall trauma conformability Late Remodeling Long lasting Trauma

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F+'+/#9#')$&*$(2&=,#9-$ Primary Patency In long lesions (> 40-50mm) fem.-pop medication training Progress of disease Recoil Flap Dissection Early Intimal hyperplasia Ongoing vessel wall trauma conformability stent covered stent Viabahn Late Remodeling Long lasting Trauma

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F+'+/#9#')$&*$(2&=,#9-$ Primary Patency In long lesions (> 40-50mm) fem.-pop Drug elution DEB-DES medication training Progress of disease Recoil Flap Dissection Early Intimal hyperplasia Ongoing vessel wall trauma conformability stent covered stent Viabahn Late Remodeling Long lasting Trauma

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Primary Patency In long lesions (> 40-50mm) fem.-pop Tack BVS D-BVS Spot-stenting Management of problems Progress of disease Recoil Flap Dissection Early Intimal hyperplasia Ongoing vessel wall trauma („conformability“) ▼ \ \ Late Remodeling Long lasting Trauma Achille's heel: foreign body The longer the lesion- the longer the stent ^ ongoing trauma

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POBA 1 ° Stents LUMINEXX SMART Protege LifeStent Astron 18 Absolute Zilver Supera DES Zilver PTX DEB Thunder Viabahn

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Studies 2007-2013 Nitinol Stents no drug POBA 1° Stents LUMINEXX SMART Protege LifeStent Astron 18 Absolute Zilver Supera Studies 2007-2013 Nitinol Stents no drug randomized

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Recoil Flap Dissektion Intimal hyperplasia (✓) Remodeling Ongoing stent trauma

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Focus on Stents accepted ind. lesions > 4-5 cm elastic recoil fl-dissection/flap calcification enlarge and stabilize vessel-lumen t = scaffold foreign body • intimal hyperpl. fracture/ong. trauma • bending • pulsatile Do not cure atheroscleros.

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