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Medizym® anti-TPO

Medizym® anti-TPO

Medizym® anti-TPO

Product catalog summary
Product Overview
Medizym® anti-TPO is an ELISA designed for the quantitative determination of IgG antibodies against thyroid peroxidase (TPO), serving as a serological marker for Hashimoto's thyroiditis. It offers excellent diagnostic efficiency with high sensitivity and specificity and is automatable for laboratory use.
Hashimoto’s Thyroiditis
This autoimmune disease is characterized by chronic inflammation of the thyroid gland, leading to hypothyroidism. It is one of the most common autoimmune diseases, affecting more women than men. Symptoms vary from hyperthyroidism at the onset to long-term hypothyroidism.
Diagnosis
Diagnosis involves clinical symptom assessment and laboratory tests for antibodies against TPO and thyroglobulin (Tg). Additional tests include thyroid hormone activity measurement and imaging techniques like sonography and scintigraphy.
Therapy
While there is no causal treatment, hormone replacement with triiodothyronine (T3) and thyroxine (T4) can manage hypothyroidism symptoms.
Medizym® anti-TPO Immunoassay
The assay uses recombinant human TPO and is calibrated with the international standard NIBSC code 66/387. It provides quantitative results in IU/mL with high precision and is CE marked. The assay demonstrates a sensitivity of 88.9% and specificity of 92.4%.
Precision and Performance
Intraassay and interassay precision were evaluated, showing consistent results across samples. The assay is designed for high-quality, routine laboratory use with ready-to-use reagents, except for the wash buffer.
Contact Information
Medipan GmbH, Ludwig-Erhard-Ring 3, 15827 Blankenfelde-Mahlow OT Dahlewitz, Germany. Phone: +49 (0) 33708 4417 0, Email: [email protected], Website: www.medipan.de
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Catalog excerpts

Medizym® anti-TPO-1

Medizym® anti-TPO ELISA for the quantitative determination of IgG antibodies against thyroid peroxidase (TPO) Product Highlights • Serological marker for Hashimoto´s thyroiditis • Excellent diagnostic efficiency with high sensitivity and specificity • Automa

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Medizym® anti-TPO-2

YOUR RELIABLE PARTNER IN AUTOIMMUNE DIAGNOSTICS 30 Years of Experience, 150 Partners in more than 100 Countries Antibodies against Thyroid Peroxidase (TPO) and their Importance in the Diagnosis of Hashimoto´s Thyroiditis Hashimoto’s Thyroiditis Clinical Symptoms Hashimoto’s thyroiditis is a polyendocrine auto- The symptoms of Hashimoto’s thyroiditis are diverse. immune disease characterized by chronic in- Due to a possible hyperthyroidism at the beginning of flammation of the thyroid gland. Antibodies, in the disease, nervousness, sweating, overactivity, in- particular against thyroid peroxidase...

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Medizym® anti-TPO-3

Medizym® anti-TPO - Enzyme Immunoassay for the quantitative Determination of IgG Antibodies against Thyroid Peroxidase (TPO) Antigen The Medizym® anti-TPO immunoassay is based on the use of recombinant human thyroid peroxidase (TPO). Calibration The Medizym® anti-TPO immunoassay is calibrated using the international standard preparation NIBSC code 66/387. Quantitative results are expressed in IU/mL. Precision The precision of test results was assessed by the determination of the intra- and interassay variation by the analysis of multiple samples with different antibody activities.

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Medizym® anti-TPO-4

Product Information Medizym® anti-TPO Medizym® anti-TPO Enzyme immunoassay for the quantitative determination of IgG antibodies against thyroid peroxidase (TPO) in human serum HIGH QUALITY - MADE IN GERMANY • Use of recombinant human thyroid peroxidase (TPO) • Ready-to-use (exception: wash buffer) and barcoded reagents • Quality assured handling in routine laboratories • Incubation at room temperature • Quantitative determination of IgG antibodies against human thyroid peroxidase (TPO) • Calibrated with the international standard preparation NIBSC code 66/387 • Results expressed in IU/mL • Excellent...

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