DEVICE FOR CARDIOVASCULAR DIAGNOSIS AND SCREENING IMPEDANCE CARDIOGRAPHY (ICG) Changes in volume and velocity of blood in the aorta cause variations in the thoracic bio-impedance which is measured and displayed as the ICG waveform. Innovative algorithms are applied to this signal to provide key haemodynamic parameters non-invasively and continuously. By means of our unique ACM-Technology in combination with the new 4TECT Sensor-Application the accuracy of the measuring method could be considerably increased and its application could be made even more simple - a new generation of Impedance Cardiography. AORTIC PULSE WAVE VELOCITY (PWV ao ) The opening of the aortic valve is defined as the B-Point in the ICG signal. The arrival of the Pulse Wave (PW) is measured on the thigh using a pressure cuff and the Propagation Time (PT) is determined. From this the aortic Pulse Wave Velocity (PWVao) can be calculated. Beginning of ventricular depolarisation PEP Pre-Ejection Period Q Opening of aortic valve Maximum systolic flow Closing of aortic valve Opening of mitral valve Left Ventricular Ejection Time Propagation Time FEATURES Enables 100% non-invasive measurement of haemodynamic parameters Continuous (beat-to-beat), real-time monitoring and recording of curves and parameters Different device configurations available according to the customer's needs Only 4 sensors necessary Application-oriented through different screens for optimal data presentation in various clinical settings Standardised and operator-independent examinations Connectable to any Windows Panel PC (touch screen), PC or Notebook Integrable & connectable Heart Rate Blood Pressure Stroke Volume/Index Cardiac Output/Index Velocity Index Acceleration Index Heather Index Pre-Ejection Period Left Ventricular Ejection Time Systolic Time Ratio Corrected Flow Time Thoracic Fluid Content VASCULAR Ankle-Brachial-Index Propagation Time aortic Pulse Wave Velocity Systemic Vascular Resistance Interface to patient monitors, such as Philips/HP (VueLink / IntelliVue / IntelliBridge) Offline data analysis and data export (e.g. Excel) Selection of available parameters

APPLICATIONS ARTERIAL STIFFNESS EVALUATION PERIPHERAL ARTERIAL OCCLUSION The Ankle-Brachial Index (ABI) enables the assessment of the overall cardiovascular risk and the early diagnosis or follow-up of peripheral arterial occlusive disease (PAOD). The CardioScreen® 2000 measures blood pressure on upper arms and ankles with four cuffs simultaneously using the oscillometric method. From this the ABI is calculated to diagnose PAODs. The measurement is fully automated and operator independent. For this reason, the CardioScreen® 2000 is a simple screening tool to detect vascular changes at an early...