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POSS

Product catalog summary

Introduction
Porcine Bonegraft is a natural bone substitute manufactured using original technology that has passed the third phase of clinical testing. It is designed for excellent pore structure, biocompatibility, and easy manipulation.

Key Features

Sticky bone formation through PRF and CGF with independent process technology.
High blood permeability and similar pH to body fluids, promoting rapid new bone formation without inflammatory reactions.
Selection of appropriate graft material sizes for optimal bone regeneration environments.
Increased micropores facilitate osteoblast migration, enhancing new bone formation.
Enhanced hydrophilicity for easy manipulation.
Applicable for various indications such as socket preservation, sinus lift, periodontal defects, and ridge augmentation.

Specifications

Available in powder and chip forms with sizes ranging from 0.2 to 2.0 mm.
Volume and weight options include 0.15 g to 2.0 g and 0.3 cc to 6.0 cc.

Clinical and Pre-Clinical Findings

Histological findings confirm the rate of new bone formation with activated osteoblasts surrounding new bones.
Clinical trials conducted with 19 test groups and 18 control groups showed similar abnormalities to the control product.
Evaluation of new bone formation and bone loss around implants demonstrated promising results.

Research and References

Studies by Jung-Wook Shin et al. and others have evaluated the osteogenic differentiation and biocompatibility of porcine bone grafts.
Comparative studies between porcine-derived and bovine-derived xenografts indicate non-inferiority in bone regeneration.

Conclusion
Porcine Bonegraft is a versatile and effective bone substitute with proven clinical efficacy and biocompatibility, suitable for various dental and orthopedic applications.

Catalog excerpts

PORCINE BONEGRAFT NATURAL BONE SUBSTITUTE

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Manufactured by /1/lGdPafk PORCINE BONEGRAFT . ggBBH Original technology which has been passed clinical test (3rd phase) Sepcifications High blood permeability, similar pH to body fluids, rapid new bone formation without inflammatory reactions Sticky bone formation through PRF and CGF with independent process technology Selection of proper size of graft materials for suitable environment for bone regeneration Increased micropores allows the migration of osteoblasts for increasing new bone formation ■ Enhanced hydrophilicity allows user to manipulate easily ■ Applicable to various indication such...

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[ Osteoblasts Differentiation Test ] [ Osteoblast Attachment ] Pre-clinical case New bone formation test (H&E Stain) : Small Animal (Rat) 4 weeks weeks 10. Histologic sections ofa,b,e,f,i,j ( ) Bio-Oss8 and Figure c,d,g,h,k,l ( 10. Histologic ) Bone-XPsections groups at ofa,b,e,f,i,j 4( weeks ) Bio-Oss andc,d,g,h,k,l ( 30 ) Bone-XP groups at 4 weeks post-surgery. a,c,e,g,i,k ( ) haematoxylin and eosin (H&E) post-surgery. stained slides; a,c,e,g,i,k ( b,d,f,h,j,l) ( ) haematoxylin Masson’sand eosin (H&E) stained slides; b,d,f,h,j,l) ( Masson’s trichrome (MT) stained slides; Arrowhead: originaldefect...

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• Conducting clinical trials with 19 test groups and 18 control groups through random allocation (Total 37 subjects) • 19 test groups (POSS), 18 control groups (Product 'B') • Clinical study results identification of equal abnormality with ‘B’ product Inorganic ingredients similar to human bones Phase name

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Case 1 Preoperative X-ray Application of POSS Fixture placement Application of Membrane Case 2 Preoperative X-ray Fixture placement Application of POSS Application of Membrane >07 WIT 2nd Surgery after 3 months Temporary prosthesis • Jung-Wook Shin et al., 2004, In vitro study of osteogenic differentiation of bone marrow stromal cells on heat-treated porcine trabecular bone blocks, Biomaterials 25 (2004) 527 535 • Jung-Wook Shin et al., 2009, Biocompatibility Evaluation of Heat-treated Mineralized Porcine Cancellous Bone-Using animal & Clinical Study, J. of Korean Orthopaedic ResearchSociety...

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Regenerative Solution Provider

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POSS

POSS

Catalog excerpts

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