Product Code and Specification Specifications Product Model - Width (±5mm) Length (±5mm) Thickness (mm) Re Dura™Biomimetic-Synthetic-Absorbable Dural Substitute References O Shi Z, Xu T, Yuan Y, Deng K, Liu M, Ke Y, et al. A new absorbable synthetic substitute with biomimetic design for dural tissue repair. Artif Organs. 2016;40:403-13. O Novel Regenerative Nanofibrous Bio-device for Dural Defect Repair. Congress of Neurological Surgeons Annual Meeting, Washing DC, USA, 2011. O In-vitro and clinical study on a novel synthetic absorbable biomimetic dural substitute. European Society for Pediatric Neurosurgery(ESPN) Congress, Rome, Italy, 2014. O Electrospum Fibrous Mats with High Porosity as Potential Scaffolds for Skin Tissue Engineering. Biomacromolecules, 2008,9(7):1795-1801. O Development of Novel Nanofibrous Dural Substitute for Dural Repair. The 14^ World Federation of Neurological Societies Interim Meeting, Pernambuco, Brazil, 2011. O Francesco Zenga, et al. Nanofibrous Synthetic Dural Patch for Skull Base Defects: Preliminary Experience for Reconstruction after Extended Endonasal Approaches. Journal of Neurological Surgery Reports 2016;77:e50-e55. O Kunxue Deng, Xun Ye, Yaya Yang, Man Liu, et al. Evaluation of efficacy and biocompatibility of a new absorbable synthetic substitute as a dural onlay graft in a large animal model. Neurological Research 2016. Rapid Repair & Regeneration Long Term SafetyExcellent Handling & Conformability High Strength & No-swelling Onlay & Suture MEDPRIN ftj Medprin Biotech GmbH Address: GutleutstraCe 163-167, 60327 Frankfurt am Main, Germany Tel: +49 69 792 160 26 Email: [email protected]

Re Dura™ Rapid repair and regeneration ReDura™ resembles microstructure of human extracellular matrix(ECM) which provides ideal scaffold for cell proliferation and tissue regeneration. ReDura™ is made of poly-L-lactic acid(PLLA), which is FDA approved and has been applied worldwide in medical devices and proven its biocompatibility and non-toxicity. Prevent cerebrospinal fluid (CSF) leakage ReDura™ is hydrophobic and acts as a physical barrier to prevent CSF leakage. No liquid leakage using ReDura™ Clinical Guide Suture procedure: Excellent conformity After hydration, ReDura™ becomes soft and...