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Megagen Implant
Evidence&Techniques MegaGen Implants

Evidence&Techniques MegaGen Implants

Product catalog summary

Introduction
MegaGen Implants has transitioned from a follower to a leader in the dental implant market since 2002, introducing innovative products like AnyRidge and AnyOne implants, and the Xpeed surface treatment. These innovations have significantly impacted implant dentistry worldwide, with a strong emphasis on clinical excellence and scientific research.

Innovative Products and Techniques
MegaGen's product line includes the narrow body Intermezzo and the short & extra wide Rescue implants, which have introduced new surgical approaches. The AnyRidge implants are particularly effective in poor density bone, offering new perspectives on implant/prosthetic treatment planning.

Research and Development
The company is engaged in prospective and multicenter controlled randomized studies to ensure product safety and efficacy. Recent publications highlight the success of their implants in various clinical scenarios, including immediate loading and rehabilitation of atrophic jaws.

Surface Treatment and Bone Materials
MegaGen focuses on improving implant surfaces and the implant-abutment interface to enhance osseointegration and long-term stability. The Xpeed surface treatment, incorporating nanostructured calcium, has shown promising clinical trial results.

Clinical Studies and Findings
Several studies have evaluated MegaGen implants, with key findings including successful rehabilitation of posterior atrophic jaws using short implants, positive outcomes with AnyRidge implants in poor density bone, effective immediate loading of fixed partial bridges in the anterior mandible, and the safety and effectiveness of maxillary early loaded titanium implants with the Xpeed surface.

Conclusion
MegaGen continues to innovate and validate their products through rigorous scientific research, inviting collaboration and further studies to advance implant dentistry.

Specifications and Procedures
The document highlights the EZ-Plus Internal implant system, emphasizing its surface quality and conical connection design. Figures illustrate the implant's macrostructure and interaction with osteoblast cells, showcasing its biocompatibility and stability.

Study 1: Short Implants vs. Augmented Bone
Short implants showed similar success rates to longer implants, with fewer complications and reduced treatment time and cost, suggesting they may be preferable in posterior mandibles.

Study 2: Short Implants in Atrophic Maxillae
Short implants were associated with fewer complications and similar patient satisfaction compared to augmented implants, offering a faster, cheaper alternative with less morbidity.

Study 3: Bone Augmentation vs. Short Implants in Posterior Jaws
Short implants showed similar outcomes to augmented implants, with fewer complications and faster recovery, though further research is needed.

Conclusion
Short implants can be a viable alternative to traditional bone augmentation techniques, offering benefits in terms of cost, treatment time, and patient morbidity, though long-term studies are necessary.

Study 1: Short Implants vs. Longer Implants in Augmented Bone
Short implants showed similar or better results compared to longer implants in augmented bone, with less bone loss and fewer complications, suggesting they may be preferable due to faster treatment, lower cost, and reduced morbidity.

Study 2: Short Implants as an Alternative Treatment
Short implants offer a high survival rate and are a viable alternative to bone regeneration techniques.

Study 3: Wide-Diameter Implants in Molar Regions
Wide-diameter implants provide a predictable treatment option in posterior areas with a survival rate of 94.9%.

Study 4: Immediate Implant Placement in Molar Sites
The novel implant system is effective for immediate placement in molar sites, suitable for experienced implantologists.

Study 5: Crestal Approach Sinus Augmentation
The technique offers a less traumatic option for patients with minimal residual bone.

Study 1: Super-Wide Short Implants in Pneumatized Maxilla
Super-wide short implants can be effectively used with limited alveolar bone height, providing good clinical outcomes and shorter post-treatment waiting times.

Study 2: Immediate Implant Placement in Molar Areas
Super-wide implants in molar areas showed a cumulative survival rate of 96.6%, emphasizing the importance of implant diameter matching the width of natural teeth.

Study 3: Immediate Loading of Fixed Partial Bridges
Immediate loading simplifies aesthetic and functional solutions for mandibular incisors.

Study 4: Immediate Implantation and Loading with Intermezzo® System
The Intermezzo® system demonstrated a 100% survival rate for immediate loading cases, effective in regions with immature bone.

Study 5: Effectiveness of Intermezzo® in Small Incisor Replacement
The narrow diameter of the Intermezzo® implant allows for stable and aesthetic replacements in areas with limited bone volume.

Conclusion
Advancements in implant technology, particularly super-wide and narrow diameter implants, have expanded possibilities for immediate implantation and loading in challenging scenarios, ensuring high survival rates and improved patient outcomes.

Study 1: Safety and Effectiveness of Maxillary Early Loaded Titanium Implants
Calcium-incorporated titanium implants are as effective and safe as conventional ones.

Study 2: Cytocompatibility and Osseointegration of Ti Implants with XPEED® Surfaces
XPEED® surfaces enhance bone integration significantly.

Study 3: Biological Cell Activity on Implants with Different Surfaces
Surface macrostructure and chemical composition influence cell activity and gene expression.

Study 4: Fabrication and Characterization of Nano-Micro Porous Titanium Surface
Anodized surfaces may enhance drug delivery and osseointegration compared to conventional surfaces.

Conclusion
Advanced surface treatments in dental implants, particularly those involving calcium incorporation and nanostructuring, enhance osseointegration and implant stability.

1. TiO2 Nanotubes and Surface Treatment
Surface texture improves osseointegration at the bone-to-implant interface, with rougher titanium surfaces enhancing cellular attachment and mineralization.

2. Cellular Activities on Alkali-Treated Titanium
Alkali-treated and blasted surfaces significantly increase cell proliferation and gene expression compared to machined surfaces.

3. Surface Characteristics of Anodized Titanium Implants
Anodized and blasted implants have higher surface roughness and release more Ca and P ions.

4. Osteoinductive and Osteoconductive Properties of Bone Substitute Material (BSM)
BSM supports cellular adhesion and new bone formation, demonstrating potential as an effective bone substitute.

5. Healing of Rabbit Calvarial Bone Defects
Biphasic calcium phosphate ceramics show significant new bone formation, outperforming other commercial bone substitutes.

6. Histomorphometric Evaluation of Bone Healing
New biphasic calcium phosphate ceramics effectively promote bone healing in rabbit models.

Introduction
The document evaluates different bone graft substitutes in rabbit calvaria, comparing a new microporous biphasic calcium phosphate (BCP) with commercial substitutes.

Materials and Methods
Four bone graft substitutes were tested, with histomorphometric evaluations conducted at 4 and 8 weeks post-surgery.

Results
BCP-1 and BCP-2 showed higher mineralized bone area percentages compared to MBCP and Bio-Oss.

Conclusion
The new BCP substitutes demonstrated osteoconductivity comparable to existing commercial products.

Additional Study
MGSB granules showed greater cell viability and proliferation, indicating potential as an effective bone graft substitute.

Key Findings
BCP materials with microporous structures are effective for bone regeneration, showing comparable or superior performance to existing products.

Catalog excerpts

Evidence &Techniques MegaGen Implants Dental Implant / Surface Treatment / Bone Materials

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Over the past decade, Megagen has gone from being a follower to a leader in the implant market. Our company, founded in 2002 by a group of dental surgeons seeking to improve their option in implant dentistry and to offer better solutions for their patients, has gone from making implants with simple improvements to a basic design to making innovative products that have changed the way implant dentistry is approached worldwide. With the narrow body Intermezzo and the short & extra wide Rescue, Megagen led the way to new surgical approaches. Never fully satisfied however, Megagen continued a vigorous...

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Evidence&Techniques MegaGen Implants Dental Implant Rehabilitation with AnyRidge implants in poor density bone - a case report. Microscopic examination of two MegaGen implant systems with conical connections. A clinical investigation of the RESCUE™ internal implant. Authors : Luigi Baggi,Gianluca Mampieri, Carlo Arullani, Michele Di Girolamo Crestal approach sinus augmentation with simulataneous superwide implant placement in Pneumatized maxilla. Immediate implant placement with super-wide implants in the molar area. Authors : Salvatore Longoni, Matteo Sartori, Nicoletta Proserpio, Santi Giuseppe...

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Surface treatment Fabrication and characterization of functionally graded nano-micro porous titanium surface by anodizing. Cellular activities of osteoblastlike cells on alkali-treated titanium surface. Sureface characteristics of titanium implant anodized after blasting treatment. Authors: Hyun-Seung Kim,Yunzhi Yang, Jeong-Tae Koh, Kyung-Ku Lee, Doh-Jae Lee, Kwang-Min Lee, Sang-Won Park Authors : Jin-Woo Park, Deog-Hye Lee, Shin-Il Yeo, Kwang-Bum Park, Seok-Kyu Choi, Jo-Young Suh Journal Name & Volume Number : The Journal of Korean Academy of Periodontology Vol. 37, No. 2(Suppl.), pp.427-445...

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Evidence&Techniques MegaGen Implants Authors: Salvatore Longoni Specialista in Chirurgia Odontostomatologica, Professore a Contratto Titolare dell’Insegnamento di Protesi Dentaria, Università degli Studi di Milano-Bicocca. Matteo Sartori Dottore di ricerca in Parodontologia Sperimentale, Professore a Contratto in Protesi Dentaria, Università degli Studi di Milano-Bicocca. Nicoletta Proserpio Specializzandi in Chirurgia Odontostomatologica, Università degli Studi di Milano-Bicocca. Santi Giuseppe Marino Dental Implant / Surface Treatment / Bone materials 01. Rehabilitation with AnyRidge implants...

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Evidence&Techniques MegaGen Implants Authors: Luigi Baggi Professore Associato di Gnatologia -Servizio di Odontoiatria Sociale e iabilitazione Gnatologica Universita di Roma “Tor Vergata - INMP“. Gianluca Mampieri Ricercatore Confermato Universita di “Tor Vergata” Carlo Arullani Specialista in Chirurgia Orale – Libero Professionista in Roma. Michele Di Girolamo Professore Aggregato Universita di “Tor Vergata” Dental Implant / Surface Treatment / Bone materials 02. Microscopic examination of two MegaGen implant systems with conical connections. - Journal: Quintessenza Internazionale Speciale 2011...

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Evidence&Techniques MegaGen Implants Authors: Enrico Conserva Professore a c. Titolare dell’Insegnamento di Riabilitazione Protesica III e IV, Universita degli Studi di Genova, Corso di Laurea Magistrale in Odontoiatria e Protesi Dentaria, (Prof. C. Campisi); Cattedra di Protesi Dentaria, (Prof. P. Pera). Libero Professionista in Albenga (Sv). Dental Implant / Surface Treatment / Bone materials 03. New guidelines in implant-prosthodontics: The tapered connection and the biological tissue preservation (BTP). - Journal: Quintessenza Internazionale Speciale 2011 Abstract: Modern implantology is...

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Evidence&Techniques MegaGen Implants Authors: Pietro Felice MD, DDS, RhD, Researcher, Department of Peridontology and Implantology, Univeristy of Bologna, Italy. Roberto Pistilli MD, Resident, Oral and Maxillofacial Unit, San Filippo Neri Hospital, Rome, Italy. Dental Implant / Surface Treatment / Bone materials 04. Posterior atrophic jaws rehabilitated with prostheses supported by 5 x 5 mm implants with a novel nanostructured calcium-incorporated titanium surface or by longer implants in augmented bone. Preliminary results from a randomised controlled trial. Fig 1. Treatment sequence of a patient...

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Evidence&Techniques MegaGen Implants Authors: Pietro Felice Department of Peridontology and Implantology, Univeristy of Bologna, Italy. Elisa Soardi Department of Peridontology and Implantology, Univeristy of Bologna, Italy. Gerardo Pellegrino Department of Peridontology and Implantology, Univeristy of Bologna, Italy. Roberto Pistilli Department of Peridontology and Implantology, Univeristy of Bologna, Italy. Claudio Marchetti 05. Treatment of the atrophic edentulous maxilla: short implants versus bone augmentation for placing longer implants. Five-month post-loading results of a pilot randomised...

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Evidence&Techniques MegaGen Implants Authors: Pietro Felice MD, DDS, PhD, Resident, Department of Periodontology and Implantology, University of Bologna, Bologna, Italy Vittorio Checchi DDS, Research Fellow, Department of Odontostomatology, Orthodontic and Surgical Sciences, Second University of Naples, Naples, Italy Roberto Pistilli MD, Resident, Oral and Maxillofacial Unit, San Filippo Neri Hospital, Rome, Italy Antonio Scarano DDS, Researcher, University of Chieti, Italy Gerardo Pellegrino DDS, Oral Surgery & Implantology Fellow, Department of Oral and Dental Sciences, University of Bologna,...

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Evidence&Techniques MegaGen Implants Authors: Marco Esposito DDS, PhD ; Freelance researcher and Associated Professor, Department of Biomaterials, The Sahigrenska Academy at Goteborg University, Sweden Dental Implant / Surface Treatment / Bone materials 07. Rehabilitation of posterior atrophic edentulous jaws : prostheses supported by 5mm short implants or by longer implants in augmented bone? One-year results from a pilot randomised clinical trial - Journal: Eur J Oral Implantol 2011;4(1:21-30) Gerardo Pellegrino DDS : Oral surgery& implantology Fellow. Department of Oral and Dental Sciences,...

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Evidence&Techniques MegaGen Implants

Evidence&Techniques MegaGen Implants

Catalog excerpts

All Megagen Implant catalogs and technical brochures