Saltus M200 Mixing System ® Over the past decade, single-use systems (SUS) and implementation of automation have been two of the pharmaceutical industry’s largest technology initiatives. Ironically, these two initiatives are not always in sync, and have moved counter to each other in application. Traditional multi-use mixing systems often incorporate PLC controls, while process control for single-use mixing systems is often far less sophisticated. Meissner’s next generation mixing platform, Saltus®, realigns these two important initiatives and provides robust, reproducible, predictable mixing...

A New Twist on Time Proven Technology The Saltus® M200 integrates well established vibromixing and single-use biocontainer technologies into a novel process solution that offers pharmaceutical manufacturers a unique alternative to reusable and disposable impeller based mixers. Vibromixing is recognized for its ability to effectively disperse microsolids in liquids. It is also exceedingly effective in liquid-liquid mixing applications, offering performance similar to stirred-tank systems, but with a much more gentle mixing action. The Saltus® mixing system’s gentle, highly effective mixing capability...

What is a Vibromixer? Vibromixers utilize a fluid agitator comprised of perforated disks attached to a shaft that is moved vertically through a fluid at a high rate of speed over a small distance. These disks contain a multitude of conical shaped openings which generate jets of liquid that move on a trajectory opposite the direction of the agitator. The resulting venturi effect induces a rapid upward flow which then cascades down the outer portion of the mixing vessel. The degree of agitation is controlled by varying the disk’s oscillation frequency. Mixing path of a single oscillating disc Mixing...

Single-Use Advantage Saltus® single-use mixing biocontainer assemblies do not require rotary seals, bearings or metallic components. Instead of relying on dynamic sealing or magnetic couplings to impart fluid motion, agitation in Saltus® single-use assemblies is accomplished via an agitator plate that is oscillated at a relatively small amplitude, but at relatively high frequency. Saltus® single-use assemblies are simply able to take advantage of the flexural properties of the TepoFlex® biocontainer to which the agitator is permanently welded. By replacing dynamic sealing with a permanent weld,...

Control System Integrated advanced functionality is controlled through a single large format HMI. All operations of the Saltus® M200, from single-use mixing assembly deployment to batch completion, are recipe driven which facilitates both ease of use and process repeatability, all via one-button process initiation. Operation of the system is protected via a three-tiered permissions level structure, and includes unique user accounts that ensure appropriate levels of interaction and track specific users’ activities. The control system features recipe storage, the ability to set user defined process...

Biocontainer Assemblies Liquid-liquid Mix 1/2" ID x 3/4" OD Tubing with Male MPX Needleless Sampling Site 3/8" ID x 5/8" OD Tubing with Male MPC Gas Inlet: 1/4" ID Tubing with Female MPC and Filter 1/2" ID x 3/4" OD Tubing with Female MPX Pressure Monitoring: 1/4" ID Tubing with Female MPC and Filter Gas Outlet 1/4" ID Tubing with Filter Ordering Information Part Number Liquid-Liquid Mixing with Single Disc Agitator Powder-Liquid Mixing with Single Disc Agitator Liquid-Liquid Mixing with Dual Disc Agitator Powder-Liquid Mixing with Dual Disc Agitator

Machine status indicator light Conveniently located tubing supports Error-proof air ingress & pressure sensor ports 200 L 304 stainless steel tank (available with jacket) 1 1/2" sanitary flange agitator connection 10 Graduated sight holes 12" color touch screen HMI Power button 11 304 stainless steel casters with non-marking, low rolling resistance urethane wheels Heavy duty 304 stainless steel hinges Ergonomic 304 stainless steel door latches with tamper evidence provisions Ordering Information Saltus® Model Tank Type 12 Locking rear access panel Nominal System Volume 09 13 External compressed...