ARACUS - Amino Acid Analyzer
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The proven gold standard Amino Aeid Analyser ACID ANALYZE

55 % faster than traditional 44 amino acids in 66 minutes

AMINO ACID ANALYZER The serie of ARACUS works according to gold standard of post column derivatization with ninhydrin, with detection at 440 nm and 570 nm using maintenance free LED photometers. A separation of up to 44 amino acids in about one hour is possible, but also of a few amino acids within a few minutes. The series of ARACUS is used in clinical laboratory (e.g. IVD newborn screening), in quality control for Food, Beverages and Feedstuff and in Research.

IMPROVEMENTS of the Next Generation: Ÿ All eluents in a separated eluent box to protect from temperature & light Ÿ Column oven more protected against external temperature influences Ÿ New damping units for improved signal-to-noise ratio Ÿ Improved reactor for better separation Ÿ New colors for a fresher design Ÿ New columns for better and faster separation Ÿ New dual photometer with reliable precision & sensitivity (ARACUS

ARACUS „classic“ Autosampler with 100 µL loop + sample rack 2x 48 vials (1.5 mL) column with column oven Reactor for post column derivatization with oven Eluents and reagent solution are selectively chosen through valves and are ideally mixed to each other. The addition of ninhydrin provides a quantitative analysis statement. A washing routine of the injection valve and syringe pump avoids cross contaminations.The level of the individual reagents can be monitored during the runs and warns the user if the quantity is no longer sufficient. The setup of the ARACUS „classic“ is the standard...

ARACUS „advanced“ The ARACUS „advanced“ is an extended configuration of the ARACUS „classic“ by an additional second pump drive. The upgraded pump configrations allows the independent operation of two fluidic lines (eluent side and reactive side). Autosampler with 100 µL loop + sample rack 2x 48 vials (1.5 mL) column with column oven Reactor for post column derivatization with oven The use of two pump drives results in an improved signal-to-noise ratio of the chromatogram. The freely adjustable parameters between the eluent and the reagent p u m p d r i ve s a l s o p rov i d e t h e...

ARACUS „lite“ The ARACUS „lite“ is a simplified configuration of the ARACUS „classic“ and designed for a reduced number of samples and smaller available budget. Due to the small sample throughput and less eluent consumption the bottles of eluents are reduced in size and makes it possible to store the eluent bottles inside of the device and the rack . The „lite“ is using the same pump configuration for operation of two fluidic lines (eluent side and reactive side) and suitable for High Speed and High Resolution columns. manual injection column with column oven Reactor for post column...

Technical Specifications method

* injection volume = 20 pL ** 780 mm with opened main unit

Determination of free/ physiological amino acids in blood plasma, serum, salvia and urine • newborn screening - Maple syrup urine disease (MSUD) - Ornithine transcarbamylase deficiency (OTC) • cardiovascular diseases Determination of hydrolysed amino acids in food, beverages and feedstuff • food Determination of biogenic amine for the investigation of metabolic processes - growth factor: T ryptamine • animal & human - neurotransmitter: Histamine, Serotonin, Dopamine etc.

ARACUS IVD The ARACUS (classic/advanced) can be used according to CE Regulation IVDR EU 2017/746. In this case a certain eluent kit certified according to IVDD 98/78/EC has to be used. There are two variants of the eluent kit IVD: Ÿ AA Eluenten-Kit IVD Ÿ AA Eluenten-Kit IVD advanced InVitro diagnostic Kit according to IVDD 98/79/EC IVD kit for the qualitative and quantitative determination of amino acids in physiological fluids like human blood and urine for medical diagnostics Each kit contains the consumables for analysis of at least 500 runs, performed with a standard program of the ARACUS...

Options Manual injection port upon request each system can be supplied as manual configuration Software 21 CFR Part 11 compliance Manual and automatic peak integration with integrated IQ/OQ procedure for software (only available with software Clarity) Inert gas It supplies the main unit and eluent box with a protective gas atmosphere by reducing the presence of atmospheric oxygen to enhance the signal to noise ratio Prime and Purge Valves Level control Active control of fluid volume by weight cell of each bottle. (only available with software Aminopeak) High Pressure side prime and purge...

Separation performance Physiological high speed Lithium system performed with the column kit Cat. No. 650-0157 and supplement kit Cat. No. 650-0162 Physiological high resolution Lithium system performed with the column kit Cat. No. 650-0126 and supplement kit Cat. No. 650-0153

Separation performance Physiological advanced plus Lithium system performed with the column kit Cat. No. 650-0178 and supplement kit Cat. No. 650-0131

Separation performance Short programm, analysis of amino acid within 15 min I & II were performed with the column kit Cat. No. 650-0157 and supplement kit Cat. No. 650-0162

Separation performance Feedstuff advanced Sodium system performed with the column kit Cat. No. 650-0165 and supplement kit Cat. No. 650-0167 Feedstuff advanced, Sodium System + amino sugars performed with the column kit Cat. No. 650-0165 and supplement kit Cat. No. 650-0167 + Cat. No. 650-0198

Separation performance Hydrolysate Sodium system performed with the column kit Cat. No. 650-0187 and supplement kit Cat. No. 650-0185 Biogenic Amine Potassium system performed with the column kit Cat. No. 650-0140 and supplement kit Cat. No. 650-0147

Columns & Supplement Kits Description Lithium High Speed Lithium High Resolution Lithium Advanced Plus Sodium High Speed Sodium High Resolution Sodium Advanced Potassium Biogenic amines * each buffer, eluent, columns and reagent can be ordered separately