The pr0ven gold standard Amino A<oid Analyser ACID ANALYZE

55 % faster than traditional 44 amino acids in 66 minutes

ACID ANALYZEI The serie of ARACUS works according to gold standard of post column derivatization with ninhydrin, with detection at 440 nm and 570 nm using maintenance free LED photometers. A separation of up to 44 amino acids in about one hour is possible, but also of a few amino acids within a few minutes. The series of ARACUS is used in clinical laboratory (e.g. IVD newborn screening), in quality control for Food, Beverages and Feedstuff and in Research.

IMPROVEMENTS of the Next Generation: Ÿ All eluents in a separated eluent box to protect from temperature & light Ÿ Column oven more protected against external temperature influences Ÿ New damping units for improved signal-to-noise ratio Ÿ Improved reactor for better separation Ÿ New colors for a fresher design Ÿ New columns for better and faster separation Ÿ New dual photometer with reliable precision & sensitivity (ARACUS

ARACUS „classic“ Autosampler with 100 µL loop + sample rack 2x 48 vials (1.5 mL) column with column oven Reactor for post column derivatization with oven Eluents and reagent solution are selectively chosen through valves and are ideally mixed to each other. The addition of ninhydrin provides a quantitative analysis statement. A washing routine of the injection valve and syringe pump avoids cross contaminations.The level of the individual reagents can be monitored during the runs and warns the user if the quantity is no longer sufficient. The setup of the ARACUS „classic“ is the standard configuration...

ARACUS „advanced“ The ARACUS „advanced“ is an extended configuration of the ARACUS „classic“ by an additional second pump drive. The upgraded pump configrations allows the independent operation of two fluidic lines (eluent side and reactive side). Autosampler with 100 µL loop + sample rack 2x 48 vials (1.5 mL) column with column oven Reactor for post column derivatization with oven The use of two pump drives results in an improved signal-to-noise ratio of the chromatogram. The freely adjustable parameters between the eluent and the reagent p u m p d r i ve s a l s o p rov i d e t h e possibility...

ARACUS „lite“ The ARACUS „lite“ is a simplified configuration of the ARACUS „classic“ and designed for a reduced number of samples and smaller available budget. Due to the small sample throughput and less eluent consumption the bottles of eluents are reduced in size and makes it possible to store the eluent bottles inside of the device and the rack . The „lite“ is using the same pump configuration for operation of two fluidic lines (eluent side and reactive side) and suitable for High Speed and High Resolution columns. manual injection column with column oven Reactor for post column derivatization...

AMINO ACID ANALYZER

* calculations according to IUPAC ** 780 mm with opened main unit

Applications Determination of free/ physiological amino acids in blood plasma, serum, salvia and urine Determination of amino acids in hydrolysed proteins Food & Beverage Meat & Fish Cheese Beer & Wine Milk Juice Tea Inborn Errors of Metabolism Metabolic Disorders Nutritional Status & Malnutrition Renal and Liver Function Monitoring Therapy Monitoring & Follow-up Newborn Screening Determination of biogenic amine for the investigation of metabolic processes Animal & Human /Neurotransmitter: Histamine, Serotonin, Dopamine etc. Plant/ Growth Factor: Tryptamine Feedstuff Poultry & Aquaculture Pig,...

ARACUS IVD The ARACUS (classic/advanced) can be used according to CE Regulation IVDR EU 2017/746. In this case a certain eluent kit certified according to IVDD 98/78/EC has to be used. There are two variants of the eluent kit IVD: AA Eluenten-Kit IVD AA Eluenten-Kit IVD advanced InVitro diagnostic Kit according to IVDD 98/79/EC IVD kit for the qualitative and quantitative determination of amino acids in physiological fluids like human blood and urine for medical diagnostics Each kit contains the consumables for analysis of at least 500 runs, performed with a standard program of the ARACUS system....

Options manual injection port Prime and purge valves easy manual injection with manual valve with a standard volume of 20 µL (other loops up on request). High Pressure side prime and purge valves in eluent and reagent flow. Inert gas Supplies the main unit and eluent box with protective gas to reduce oxygen & enhance Signal/Noise ratio. Level control Software 21 CFR Part 11 Manual and automatic peak integration with integrated IQ/OQ procedure for software. Active control of fluid volume by weight cell of each bottle. !!! Fluorescence detector for sensitive OPA-based detection of primary amines....

Separation performance High Speed Physiological High Speed Lithium system performed with the column kit Cat. No. 650-0157 and supplement kit Cat. No. 650-0162 Hydrolysate High Speed Sodium system performed with the column kit Cat. No. 650-0187 and supplement kit Cat. No. 650-0185

Separation performance High Resolution Physiological High Resolution Lithium system performed with the column kit Cat. No. 650-0126 and supplement kit Cat. No. 650-0153 or 650-0146 (IVDD 98/78/EC) Hydrolysate High Resolution Sodium system performed with the column kit Cat. No. 650-0190 and supplement kit Cat. No. 650-0196

Separation performance others AMINO ACID ANALYZER performed with the column kit Cat. No. 650-0157 and supplement kit Cat. No. 650-0162 For additional short programs, please contact us!

Separation performance Advanced (Ph. Eu. 2.2.56) Physiological Advanced Plus Lithium System performed with the column kit Cat. No. 650-0178 and supplement kit Cat. No. 650-0131 Asy: ASP 1.098, Res: GLY-ALA 2.242, CYS2-ASA 2.062, ILE-CHD: 1.666, NLE-TYR 1.913, TYR-PHE 4.229 Analytical chromatogram shown in two sections for better visualization.