ZZNIT autoimmunity Fully automated IFA analyzer A different way to be unique Total automation Unparalleled performance Enhanced standardization

Evolving scenarios and innovative perspectives Autoimmune diseases and the role of IFA The impact of autoimmune diseases has grown exponentially both from a clinical and a diagnostic point of view over the past few decades. The knowledge of the pathogenic mechanisms underlying autoimmune diseases contributed to identify new autoantibodies and new diagnostic/prognostic assays have been developed. Antinuclear antibodies (ANA) are important elements in the diagnosis of a variety of autoimmune diseases, especially ANA-associated rheumatic diseases (AARD), and indirect immunofluorescence (IFA), although...

A generation ahead in IFA automation The evolution of standardization Zenit PRO is the new high-performance A.Menarini Diagnostics fully automated system which streamlines the whole IFA protocol, from slide processing to reading and interpretation of results. The system integrates an enhanced module that ensures the complete slide preparation, from serum dilution to coverslipping, with an on-board reading unit which provides unparalleled accuracy and allows automated whole well digitization for a better interpretation of Zenit IFA tests. What makes Zenit PRO different are the image autofocusing...

Driving standardization through automation Integrated slide processing that changes the way IFA is performed A. Menarini Diagnostics brought engineering and capability to the lab by simply developing the sole system that ensures the complete preparation of the IFA slide, from serum dilution to coverslipping, minimizing operator intervention all along a high-volume testing procedure. Sample dispensation The Zenit PRO automated liquid handling system eliminates the inconsistency of human intervention, maximizing the accuracy of the overall IFA process and ensuring accurate sample dispensation,...

Fully automated IFA analyzer 1 More needles for higher speed Two dispensing needles and one aspiration needle increase preparation speed Automated coverslipping and mounting The system automatically mounts each processed slide. A suction pad places the coverslip and seals the slide, avoiding the formation of air bubbles Multiple run Up to 18 slides can be simultaneously loaded to be processed. Zenit PRO allows continuous access to add further tests while the system is operating Wash station A wash station ensures both internal and external cleaning of the three needles eliminating carryover Automated...

ZZNIT PRO autoimmunity Fully automated IFA analyzer From assay to answer Advanced and powerful information management for results that matter Zenit PRO offers powerful analytics and a simple and intuitive user interface that simplify workflows and enable meaningful analysis of results to efficiently achieve diagnostic goals even from the most challenging assays. Simply powerful The system can process and scan a number of cellular substrates and provides whole well digitization of any IFA Zenit test: it performs the analysis on the whole well and not just on a limited number of pre-defined images...

Technical Specifications ZENIT autoimmunity PRO Fully automated IFA analyzer Add confidence to your results Slide processing Pumps Traceability The system includes the automatic classification of positive/negative results for Zenit ANA HEp-2 tests and the identification of a number of cellular patterns even in mixed cases. The software measures the intensity of fluorescence for each positive test and provides a pattern suggestion based on a wide database of reference images used to train a state of the art classifier. Additional recognition software modules Zenit ANA HEp-2 pattern recognition Smart...

Austria A. Menarini GmbH Pottendorfer Strasse 25-27 A-1120 Wien, Austria Tel, +43-1-80415760 Fax +43-1-8043194 www,menarinidiagnostics,at Belgium A. Menarini Diagnostics Benelux S.A/N.V. Belgicastraat 4 1930 Zaventem, Belgium Tel, +32-2-7214545 Fax +32-2-7209292 www,menarinidiagnostics,be France A. Menarini Diagnostics France S.A.R.L. 3-5, rue du Jura - BP 7051 1 94633 Rungis Cedex, France Tel, +33-1-56346910 Fax +33-1-56346911 www,menarinidiagnostics,fr Germany A. Menarini Diagnostics Deutschland Eine Division der Berlin Chemie AG Glienicker Weg 125 - 12489 Berlin, Germany Tel, +49-30-67073000 Fax...