We dedicate our heart and passion into medical care Our Mission “We want to save lives” - This has always been our greatest motivation In 1984, we successfully developed and commercialized the world’s first piston-type HFO (High Frequency Oscillation) mechanical ventilator. It was clinically evident that HFO ventilation would be superior to conventional methods, but the commercialization of HFO had always been considered extremely difficult. At the time, we said to ourselves, “if we can turn this into a reality, we can save so many premature newborn lives that no others can save today” – this aspiration drove us to take this difficult technological challenge where nobody else had succeeded. Through repeated trial and error, we finally completed our first product. We took this product to be evaluated for use in the world’s first large-scale clinical trial for HFO ventilation, called the “HiFi Trial” sponsored by the NIH (the United States National Institute of Health), and was chosen as the preferred HFO ventilator over numerous other ventilators submitted by various manufacturers throughout the world. Since then, our HFO ventilators have been steadily evolving through our successive research and development efforts. We are enormously proud that our HFO ventilators have been installed and used in more than 90% of Japan’s NICUs (neonatal intensive care units) and contributes to Japanese premature neonatal care that is considered to be the world’s best. As a critical-care medical device developer and manufacturer, we have absolute conviction in ourselves – our job is not to force patients to adapt to our technologies, but we must rather advance our technologies so that our products will coincide with what patients and their conditions require. It is our strong belief that the developer’ s “heart” and “passion” can only make such an ideal a reality. With this in mind, we will continue our challenging journey. Group Chairman, Metran Co., Ltd.

From state-of-the-art critical-care medical devices to home healthcare and veterinary support, we will continue to support patients waiting for Metran’s “one of a kind” medical devices Our desire is to develop products that can help people rejoice in human life, no matter what their medical condition It is an unfortunate fact that there are still many premature newborns in the world that pass away beyond help. There are also many patients who are having a difficult time just breathing at home every day. As well, there are countless people who are forced into uncomfortable and sometimes unbearable...

With a fusion of expert hardware and software engineering, we have opened up the future of mechanical ventilation We possess the technological development capabilities that allowed us to successfully develop and commercialize the world’s only piston-type HFO ventilator Although there are different types of HFO ventilators available today, the piston-type oscillator is considered the most gentle and the safest approach to manage the respiratory needs of challenging patient scenarios, especially to treat the lungs of premature newborns. Metran is the only company in the world that has successfully...

In an effort to provide the highest level of technological development that is expected at the leading edge of medical practice Exceptional communication and interaction is critically essential in research and development We are constantly striving to increase our knowledge by studying and learning leading edge research, by reading clinical papers and publications as well as participating in global medical standards meetings and clinical conferences. Moreover, through our close communication and interaction with clinicians who are playing a critical role in the front line of clinical practice,...

From the hospital ICU to home healthcare settings, Metran’s products are playing a critical role in various clinical scenes A state-of-the-art piston-type HFO ventilator that brings together over 30 ( Oxygen concentrator ) years worth of technological achievements. The Humming Vue provides not Homecare oxygen therapy only HFO mode but also all popular conventional and spontaneous supportive device. Battery-powered, ventilation modes in order to effectively and swiftly support a wide range of compact, lightweight and extremely patient conditions as well as enhancing speedy recovery of patients...

Corporate Philosophy Our goal is to develop “thoughtful” medical devices Our “heart” is to listen and respond to the needs and requests of clinicians, making sure that our products are truly good and comfortable for patients, and be absolutely safe and reliable. Our goal is to develop and provide “One-and-Only” technologies and products We continually strive to provide medical devices that are possible only by Metran. We at Metran are all partners sharing the same aspiration We, as Metran employees, together strive to meet the needs and expectation of healthcare market, and serve a meaningful...

Company History 1984 [ Metran Co., Ltd. ] founded as a manufacturer of medical equipment. Development of the "Hummingbird" High Frequency Oscillation (HFO) artificial ventilator begins. 1984 "Hummingbird" enters a competition sponsored by the National Institutes of Health (NIH) for HFO ventilators in the U.S., winning first prize among ventilators from 8 different manufacturers around the world. Metran receives an order for 85 "Hummingbird" ventilators to be used in the first clinical trial of its kind in the world. Development and manufacturing begins on the SAV-6 artificial ventilator for veterinary...

Group Affiliate Organization Name: 37-37A Dong Ho, Phuong 8, Quan Tan Binh, Ho Chi Minh City, Viet Nam Tel: (84) 8-3864-0528 Fax: (84) 8-3864-0622 Paid-In Capital: Principle of Business: Manufacture and sales of medical devices and equipment Main Bank: Vietcom Bank Organization Name: METRAN VIETNAM CO., LTD. (VIETNAM) 37-37A Dong Ho, Phuong 8, Quan Tan Binh, Ho Chi Minh City, Viet Nam Tel: (84) 8-3864-0528 (84) 8-3971-2552 Fax: (84) 8-3864-0622 Paid-In Capital: Hoang Khoi Ngoc Principle of Business: Software and electrical hardware development Organization Name: METRAN VITEC CO., LTD. (VIETNAM)...