1. Catalogs
  2. MILESTONE
  3. PrestoCHILL Catalog

PrestoCHILL Catalog

PrestoCHILL Catalog

PrestoCHILL Catalog

Product catalog summary
Introduction
The document introduces the Presto CHILL technology, a breakthrough in cryoembedding for frozen sections, particularly effective for fatty tissues. It highlights the combination of Presto CHILL with the PRESTO PRO automatic processor/stainer to achieve permanent-like quality in frozen sections.

Specifications
The Presto CHILL is a benchtop cryoembedding station featuring a Stirling cooler freezing module, an anodized aluminum freezing platform, and a 4.3” touchscreen terminal. It weighs 22 kg and operates on a power supply of 230V or 115V. The dimensions are 45 cm in height, 30 cm in width, and 54 cm in depth.

Procedures
The process involves cryoembedding biospecimens, cutting sections, and automated slide processing/staining. The freezing time is reduced to 60 seconds, eliminating artifacts and allowing for easy cutting of fatty tissues without distortion. The patented face-down embedding technique ensures flat plane surfaces, reducing trimming time.

Norms and Recommendations
The system operates without liquid nitrogen, CO2, or isopentane, making it an all-dry system. It is recommended for use in Mohs surgery and other delicate tissue processing, offering a safe and rapid solution.

Key Features
- Ultrafast freezing prevents ice crystal formation.
- Supports high throughput operations with up to 6 samples frozen in parallel.
- MCC compound provides optimal support during cryotomy and is water-soluble, leaving no residue.

Accessories
Includes lens paper disks for easy mounting and a variety of molds to fit different requirements. An automatic defrost cycle ensures 24/7 operations.

Conclusion
The Presto CHILL technology redefines frozen section processing, offering a rapid, efficient, and artifact-free solution for high-quality tissue sections.
See more

Catalog excerpts

PrestoCHILL Catalog-1

Presto CHILL The game changer in cryoembedding for frozen sections of permanent-like quality

 Open the catalog to page 1
PrestoCHILL Catalog-2

THE PRESTO TECHNOLOGY: PrestoCHILL The goal of frozen sections permanent-like quality can be achieved by combining the advanced cryoembedding technology of the Presto CHILL unit, with the performance of the PRESTO PRO automatic processor/stainer. Presto CHILL Your cryostat Automated slide’s processing/staining From fresh biospecimens to six stained frozen sections of permanent-like quality in less than 10 minutes. Frozen Sections | Presto CHILL

 Open the catalog to page 2
PrestoCHILL Catalog-3

NEED GOOD RESULTS? START WITH A GOOD PREPARATION The optimal frozen section begins with an evenly and completely frozen tissue block in which, the block face to be sectioned is flat and includes a complete, full faced section of the tissue submitted. The section should be free of ice crystal artifacts, knife lines and/ or tears. The speed and simplicity of Presto CHILL’s operations revolutionize the rapid freezing process, keeping the microscopic appearance of tissues “true-to-life”. Presto CHILL - Benchtop cryoembedding station TIME TO REDEFINE FROZEN SECTIONS Reduce freezing time to 60 seconds....

 Open the catalog to page 3
PrestoCHILL Catalog-4

Presto CHILL. THE FIRST STEP TOWARDS HIGH-QUALITY FROZEN SECTIONS Heat extractors 6 removable aluminum molds with a diameter of 25-30 mm. (Other sizes and shapes are available) Chuck freezing area Touch screen terminal (4.3“) USB port for full documentation Cool trap for the defrost step THIS IS HOW CRYOEMBEDDING SHOULD BE NO FREEZING ARTIFACTS 60 SECOND FREEZING TIME AN ALL-DRY SYSTEM FULL DOWNLOADABLE DOCUMENTATION NO LIQUID NITROGEN NO CO2 - NO ISOPENTANE NO CRYOSTAT’S FREEZING Frozen Sections | Presto CHIL

 Open the catalog to page 4
PrestoCHILL Catalog-5

SIMPLE. INTUITIVE OPERATIONS Place a drop of cryoembedding compound on the tip of the spatula. Transfer the specimen to the bottom of the mold. Add the cryo-embedding compound to fill the mold. Place the chuck into the mold. Add the extractor and close the cover. Start the timer. After 60 seconds... ... A frozen block with a perfectly “flat plane” surface is ready for cutting. WHAT SETS US APART ? THE UNIQUE COMBINATION OF THE PATENTED* FACE-DOWN EMBEDDING TECHNIQUE, TOGETHER WITH A STATE-OF-THE-ART, RAPID STIRLING COOLING DEVICE AT -40°C. Frozen Sections | Presto CHI

 Open the catalog to page 5
PrestoCHILL Catalog-6

FROZEN SECTIONS OF PERMANENT-LIKE QUALITY OF FATTY TISSUES. This is a frozen section of human breast obtained in 13 minutes or less! Breast and fatty tissues in general are some of the most difficult tissues to process as frozen sections. With the Presto CHILL, Milestone has developed a breakthrough freezing technology, which combined with the patented “face down embedding” technique and with dedicated protocols for automatic processing and staining of frozen sections, offers an innovative and rapid solution to this challenge. THE MILESTONE’S BREAKTHROUGH CRYOEMBEDDING FOR FATTY TISSUES. TRIMMING...

 Open the catalog to page 6
PrestoCHILL Catalog-7

CRYOEMBEDDING OF DELICATE TISSUES - SMALL FRAGMENTS/MOHS SURGERY During the practice of frozen section pathology, pathologists often encounter the task of embedding tissues that are extremely delicate because of the nature of their consistence and structure. This is a situation that occurs daily during Mohs surgery, in which the technologist handles delicate slivers of skin with the goal of accurately embedding these tissues to completely visualize the epidermis and its margin. The Presto CHILL paper embedding technique offers a safe and rapid solution to these problems. **The Art of Embedding...

 Open the catalog to page 7
PrestoCHILL Catalog-8

ACCESSORIES FOR EASIER OPERATION MCC an optimized cryoembedding compound Lens paper disks for easy mounting MCC is a proprietary formulation of glycols and resins specifically developed for optimal support during cryotomy of dissected tissues down to -40°C. Being water soluble, MCC doesn’t leave Lens paper disks are an excellent support for freezing residue on the slides, eliminating small fragments or delicated specimens making the non specific background staining. diffucult task simple and rapid. Available in 3 sizes Additionally, MCC will not dull microtome knives. Molds to fit every requirement...

 Open the catalog to page 8
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.